GSE121894

Gene expression profile of endothelial cells derived from circulating progenitors issued from patients with rheumatoid arthritis

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

18 case / 40 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Summary

Synovial neoangiogenesis is an early and crucial event to promote the development of the hyperplasic proliferative pathologic synovium in rheumatoid arthritis (RA). Endothelial cells (ECs) are critical for the formation of new blood vessels since they highly contribute to angiogenesis and vasculogenesis. To better characterize these cells, our group has studied the gene expression profiles of ECs issued from 18 RA patients compared to 11 healthy controls.

Overall design

ECs derived from circulating endothelial progenitor cells (EPCs) were isolated from peripheral blood of RA patients and controls for RNA extraction and hybridization on Affymetrix microarrays. Gene expression profiles of EPC-derived ECs were determined in basal conditions and also after hypoxic exposure.

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
58 GSM samples
Primary source
recount3

Planned trusted source for processed count availability.

No match found
Expression Atlas

Planned source for curated expression experiment links.

No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

2 linked publications 2 DOIs

Related publications

  1. Inokosterone Is A Potential Drug Target of Estrogen Receptor 1 in Rheumatoid Arthritis Patients: Analysis from Active Ingredient of Cyathula Officinalis. Chinese journal of integrative medicine, 2021
  2. Bone Marrow Mesenchymal Stem Cells Release miR-378a-5p-Carried Extracellular Vesicles to Alleviate Rheumatoid Arthritis. Journal of innate immunity, 2023
Available

Metadata Quality Components

Analysis Readiness

Ready after review
97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

  • Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
  • Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Tumor vs normal
Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
  • Disease context Rheumatoid arthritis Disease context came from Normalization rules.
  • Likely case group Rheumatoid arthritis 18 samples
  • Likely control group Mixed controls 40 samples

Intent Interpretation

  • Downgrade or exclusion reason Downgraded for tissue search because it is a biofluid cohort. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Comparison: Disease/model vs control. Specimen: Biofluid. Comparison suitability: 0%.
  • Interpreted disease metadata: Rheumatoid arthritis.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 2 publications; 2 DOIs available: PMID 34432202, PMID 37926093.
  • Publication context: Inokosterone Is A Potential Drug Target of Estrogen Receptor 1 in Rheumatoid Arthritis Patients: Analysis from Active Ingredient of Cyathula Officinalis.. Chinese journal of integrative medicine, 2021. PMID 34432202. DOI 10.1007/s11655-021-3492-5.
  • Publication context: Bone Marrow Mesenchymal Stem Cells Release miR-378a-5p-Carried Extracellular Vesicles to Alleviate Rheumatoid Arthritis.. Journal of innate immunity, 2023. PMID 37926093. DOI 10.1159/000534830.

Cautions

  • Downgraded for tissue search because it is a biofluid cohort.
  • Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
  • Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
  • Blood, plasma, or serum cohort downgraded because this ranking targets tissue tumor-vs-normal comparisons.
  • Microarray expression context downgraded below primary bulk RNA-seq for the default tissue ranking.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Overall score capped because microarray cohorts should be compared separately from RNA-seq cohorts.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Normalized Fields

252 fields

Sample Group Preview

58 rows shown
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Study totals: Case 18 | Control 40 | Unassigned 0 | Excluded 0 | Ambiguous 0 58 rows shown
Group Role Accession Title Source / characteristics Reason
Rheumatoid arthritis Case GSM3449621 RA EPC-derived endothelial cells - hypoxia - 1 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449623 RA EPC-derived endothelial cells - hypoxia - 2 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449625 RA EPC-derived endothelial cells - hypoxia - 3 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449627 RA EPC-derived endothelial cells - hypoxia - 4 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449629 RA EPC-derived endothelial cells - hypoxia - 5 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449631 RA EPC-derived endothelial cells - hypoxia - 6 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449633 RA EPC-derived endothelial cells - hypoxia - 7 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449635 RA EPC-derived endothelial cells - hypoxia - 8 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449637 RA EPC-derived endothelial cells - hypoxia - 9 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449639 RA EPC-derived endothelial cells - hypoxia - 10 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449641 RA EPC-derived endothelial cells - hypoxia - 11 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449643 RA EPC-derived endothelial cells - hypoxia - 12 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449645 RA EPC-derived endothelial cells - hypoxia - 13 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449647 RA EPC-derived endothelial cells - hypoxia - 14 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449649 RA EPC-derived endothelial cells - hypoxia - 15 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449651 RA EPC-derived endothelial cells - hypoxia - 16 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449653 RA EPC-derived endothelial cells - hypoxia - 17 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Rheumatoid arthritis Case GSM3449655 RA EPC-derived endothelial cells - hypoxia - 18 EC derived from circulating EPCs_RA_hypoxic exposure Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Case marker detected.
Untreated Control GSM3449622 RA EPC-derived endothelial cells - basal - 1 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449624 RA EPC-derived endothelial cells - basal - 2 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449626 RA EPC-derived endothelial cells - basal - 3 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449628 RA EPC-derived endothelial cells - basal - 4 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449630 RA EPC-derived endothelial cells - basal - 5 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449632 RA EPC-derived endothelial cells - basal - 6 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449634 RA EPC-derived endothelial cells - basal - 7 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449636 RA EPC-derived endothelial cells - basal - 8 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449638 RA EPC-derived endothelial cells - basal - 9 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449640 RA EPC-derived endothelial cells - basal - 10 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449642 RA EPC-derived endothelial cells - basal - 11 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449644 RA EPC-derived endothelial cells - basal - 12 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449646 RA EPC-derived endothelial cells - basal - 13 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449648 RA EPC-derived endothelial cells - basal - 14 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449650 RA EPC-derived endothelial cells - basal - 15 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449652 RA EPC-derived endothelial cells - basal - 16 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449654 RA EPC-derived endothelial cells - basal - 17 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449656 RA EPC-derived endothelial cells - basal - 18 EC derived from circulating EPCs_RA_basal conditions Subject status: Rheumatoid arthritis; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Untreated Control GSM3449657 Control EPC-derived endothelial cells - basal - 1 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449658 Control EPC-derived endothelial cells - hypoxia - 1 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449659 Control EPC-derived endothelial cells - basal - 2 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449660 Control EPC-derived endothelial cells - hypoxia - 2 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449661 Control EPC-derived endothelial cells - basal - 3 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449662 Control EPC-derived endothelial cells - hypoxia - 3 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449663 Control EPC-derived endothelial cells - basal - 4 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449664 Control EPC-derived endothelial cells - hypoxia - 4 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449665 Control EPC-derived endothelial cells - basal - 5 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449666 Control EPC-derived endothelial cells - hypoxia - 5 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449667 Control EPC-derived endothelial cells - basal - 6 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449668 Control EPC-derived endothelial cells - hypoxia - 6 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449669 Control EPC-derived endothelial cells - basal - 7 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449670 Control EPC-derived endothelial cells - hypoxia - 7 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449671 Control EPC-derived endothelial cells - basal - 8 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449672 Control EPC-derived endothelial cells - hypoxia - 8 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449673 Control EPC-derived endothelial cells - basal - 9 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449674 Control EPC-derived endothelial cells - hypoxia - 9 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Healthy control Control GSM3449675 Control EPC-derived endothelial cells - hypoxia - 10 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449676 Control EPC-derived endothelial cells - basal - 10 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.
Healthy control Control GSM3449677 Control EPC-derived endothelial cells - hypoxia - 11 EC derived from circulating EPCs_healthy control_hypoxic exposure Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Hypoxic exposure Sample-local control marker detected.
Untreated Control GSM3449678 Control EPC-derived endothelial cells - basal - 11 EC derived from circulating EPCs_healthy control_basal conditions Subject status: Healthy control; Tissue: Peripheral blood; Cell type: Endothelial cells (EC) derived from circulating endothelial progenitor cells (EPCs); Treatment: Unstimulated Treatment control marker detected.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.