GSE122618

Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational strategies based on Systems Biology.

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: bulk RNA-seq
Organism: Homo sapiens
Whole-study samples: 46 samples
Specimen: Biofluid
Reported/interpreted study design: Unclear study design Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Lorén V, Manyé J, Sumoy L
Contact name: Lauro Sumoy
Submission date: 2018-11-16
Last update: 2022-03-31
Organization: IGTP
Department: High Content Genomics and Bioinformatics
Public date: 2022-03-30
Experiment types: Non-coding RNA profiling by high throughput sequencing
Platforms: GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Series type: Series
SubSeries: Not available
BioProject: PRJNA505782

Summary

Our group used rectal biopsies from patients with active ulcerative colitis (UC) and differential response to glucocorticoid treatment, to generate a predictive computational strategy based on systems biology. Contrasting mRNA and miRNAs intestinal expression profiles with updated molecular information related to UC and glucocorticoids, we were able to identify a mechanism of action (MoA) associated with corticosteroid failure in UC. ith the aim of transferring these results to clinical practice, the MoA-models created previously were implemented with plasmatic miRNAs profiles, to describe in silico non-invasive potential biomarkers of glucocorticoid refractoriness. Small RNA-seq analysis was perfomed using Illumina next generation sequencing and standard statistical criteria were applied to compare the miRNA profiles, incluidng paired samples before clucocorticoid treatment to the third day of the steroidal treatment. The selection these miRNA with predictive capacity was done using two complementary strategies: the first one using all the obtained miRNAs, and the second taking into account those miRNAs that are directly related to MoA, through various statistical restrictions (RELIEF, ENTROPY + CORRELATION, WILCOXON, ROC, and simple REGRESSION). These computational approaches from all miRNAs identified hsa-miR218-5p as the best to classify patients according their respond at basal time (Accuracy = 84.21%, Generalization Capability = 84.21%, Sensitivity = 100% and Specificity = 66.67%). In addition, the combination of this miRNA with hsa-miR6754-5p and hsa-miR4767, increases the diagnosis accuracy of the disease (Accuracy = 94.74%, Generalization Capability = 75.44%, Sensitivity = 70% and specificity = 81.48%). On the other hand, the combination of hsa-miR218-5p and the plasma levels of the Protein C Reactive increases the ability to classify patients towards their response to glucocorticoids up to 89%. Taking in account all this data, we can conclude that by means of a computer strategy based on Biology of Systems we have identified the plasmatic miR-218-5p as a potential biomarker to glucocorticoid response in UC before start the treatment.

Overall design

In total 46 samples were analyzed: 7 reference and 39 UC patient samples, derived from 27 different individuals (7 healthy controls and 20 patients). There were two patient groups based on glucocorticoid treatment response, composed of 10 responders and 10 non-responders respectively. Patient samples were collected at two different times: before and three days after glucocorticoid treatment. In total there were 19 sets of paired patient samples, before and after treatment from each of 19 diferent individual patients, and a single odd sample taken after treatment from the 20th patient.

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 46 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Planned source for curated expression experiment links.	No match found
PubMed	Primary GEO citations and related PubMed articles that mention this dataset. 1 linked publication 1 DOI Primary publication ANP32E, a Protein Involved in Steroid-Refractoriness in Ulcerative Colitis, Identified by a Systems Biology Approach. Journal of Crohn's & colitis, 2019 PubMed DOI	Available

Metadata Quality Components

Persisted metadata quality

93 pts

Clarity: 93%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Only one side of the comparison is clearly grouped. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Not ready

55% DE readiness

Contrast completeness

10/25 pts

Only one side of the contrast is present; downstream DE needs both groups.

Minimum group size

0/20 pts

Minimum group size cannot be evaluated until a complete contrast exists.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

0/10 pts

Critical warnings must be resolved before downstream analysis.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No complete case/control contrast is available.
Critical dataset warnings must be resolved.
Secondary RNA assay context should be analyzed separately from ordinary bulk RNA-seq.

Next Steps

Resolve critical warnings before downstream analysis.

Analysis Preparation Checklist

4/6 ready

Group labels reviewed

Blocked

No complete case/control grouping exists yet.

Review the sample grouping table and assign both case and control groups.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Analysis readiness has blockers that must be resolved before DE.

Analysis preparation checklist contains blocked items.

No complete case/control or treatment/control contrast is available.

At least one comparison group has fewer than two samples.

Critical dataset warnings are present.

Assay context may require expert handling before DESeq2-style analysis.

Study design is model-system or unclear and should be reviewed before analysis.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Disease context Inflammatory bowel disease, ulcerative colitis Disease context came from Normalization rules.
Likely case group Inflammatory bowel disease 46 samples
Likely control group No control group detected 0 samples

Intent Interpretation

Downgrade or exclusion reason Comparison: Unclear study design. Specimen: Biofluid. Comparison suitability: 0%. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Inflammatory bowel disease, Ulcerative colitis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 30329026.
Publication context: ANP32E, a Protein Involved in Steroid-Refractoriness in Ulcerative Colitis, Identified by a Systems Biology Approach.. Journal of Crohn's & colitis, 2019. PMID 30329026. DOI 10.1093/ecco-jcc/jjy171.

Cautions

Comparison: Unclear study design. Specimen: Biofluid. Comparison suitability: 0%.
Downgraded for tissue search because it is a biofluid cohort.
Downgraded for tissue search because study design or specimen source is unclear.
Blood, plasma, or serum cohort downgraded because this ranking targets tissue tumor-vs-normal comparisons.
Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Missing or unclear metadata. Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Small RNA, miRNA, circRNA, or extracellular-vesicle RNA context downgraded for primary mRNA tissue ranking.
Overall score capped because comparison suitability is weak for the selected search intent.
Overall score capped because secondary RNA assays are not primary mRNA tissue RNA-seq.
Missing or unclear metadata. Comparison - Unclear study design. Specimen - Biofluid. Comparison suitability: 0%.
Missing or unclear metadata. Downgraded for tissue search because study design or specimen source is unclear.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

No clear control group was detected from normalized metadata.
Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.
Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis.
Patient-tissue tumor-normal intent requires clear tumor-normal grouping.

Normalized Fields

97 fields

Field Value Source Derived by Confidence Evidence Reason

assay_type bulk RNA-seq GSE122618 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence bulk rna-seq dataset_accession: GSE122618 dataset_title: Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational s... keyword match keyword match: bulk rna-seq

disease ulcerative colitis GSE122618 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis dataset_accession: GSE122618 dataset_title: Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational s... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease inflammatory bowel disease GSM3476321 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC1 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 56; Sex: Male; individual: VC1; sample type: plasma controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476322 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC2 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 54; Sex: Female; individual: VC2; sample type: pl... controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476323 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC5 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 68; Sex: Male; individual: VC5; sample type: plasma controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476324 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC6 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 59; Sex: Female; individual: VC6; sample type: pl... controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476325 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC8 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 56; Sex: Female; individual: VC8; sample type: pl... controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476326 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC9 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 44; Sex: Female; individual: VC9; sample type: pl... controlled vocabulary controlled vocabulary disease match: ibd

disease inflammatory bowel disease GSM3476327 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd VC11 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 71; Sex: Female; individual: VC11; sample type: ... controlled vocabulary controlled vocabulary disease match: ibd

disease ulcerative colitis GSM3476328 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0074.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 59; Sex: Male; individual: 74... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476329 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1359.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 37; Sex: Female; individual: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476330 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1267.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 39; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476331 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1289.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 22; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476332 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0168.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 46; Sex: Female; individual: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476333 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1306.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 60; Sex: Male; individual: 13... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476334 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0773.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 25; Sex: Male; individual: 77... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476335 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0039.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 50; Sex: Male; individual: 39... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476336 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1229.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 43; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476337 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0285.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 83; Sex: Male; individual: 28... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476338 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0714.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 26; Sex: Male; individual... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476339 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1213.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 28; Sex: Female; individu... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476340 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1106.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 26; Sex: Female; individu... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476341 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0462.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 55; Sex: Male; individual... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476342 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0577.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 82; Sex: Female; individu... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476343 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1238.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 49; Sex: Female; individu... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476344 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1279.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 72; Sex: Male; individual... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476345 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0730.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 34; Sex: Female; individu... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476346 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1193.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 32; Sex: Male; individual... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476347 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1306.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 60; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476348 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0773.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 25; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476349 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0285.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 83; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476350 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0039.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 50; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476351 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1229.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 43; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476352 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0074.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 59; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476353 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1267.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 39; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476354 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1289.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 22; Sex: Male... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476355 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0168.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 46; Sex: Fema... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476356 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1359.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 37; Sex: Fema... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476357 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0714.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 26; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476358 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1213C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 28; Sex: F... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476359 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1106.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 26; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476360 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0462.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 55; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476361 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0577.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 82; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476362 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1238.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 49; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476363 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1279.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 72; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476364 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 0730.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 34; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476365 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1193.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 32; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM3476366 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC 1416.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 30; Sex: ... controlled vocabulary controlled vocabulary disease match: UC

organism Homo sapiens GSE122618 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence homo sapiens dataset_accession: GSE122618 dataset_title: Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational s... keyword match keyword match: homo sapiens

specimen_material plasma GSM3476321 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC1 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 56; Sex: Male; individual: VC1; sample type: plasma controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476322 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC2 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 54; Sex: Female; individual: VC2; sample type: pl... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476323 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC5 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 68; Sex: Male; individual: VC5; sample type: plasma controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476324 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC6 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 59; Sex: Female; individual: VC6; sample type: pl... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476325 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC8 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 56; Sex: Female; individual: VC8; sample type: pl... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476326 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC9 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 44; Sex: Female; individual: VC9; sample type: pl... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476327 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma VC11 plasma disease state: reference; corticosteroid response: No IBD treatment; collection time: no IBD treatment; age (years): 71; Sex: Female; individual: VC11; sample type: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476328 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0074.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 59; Sex: Male; individual: 74... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476329 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1359.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 37; Sex: Female; individual: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476330 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1267.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 39; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476331 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1289.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 22; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476332 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0168.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 46; Sex: Female; individual: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476333 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1306.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 60; Sex: Male; individual: 13... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476334 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0773.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 25; Sex: Male; individual: 77... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476335 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0039.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 50; Sex: Male; individual: 39... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476336 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1229.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 43; Sex: Male; individual: 12... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476337 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0285.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: before glucocorticoid treatment; age (years): 83; Sex: Male; individual: 28... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476338 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0714.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 26; Sex: Male; individual... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476339 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1213.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 28; Sex: Female; individu... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476340 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1106.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 26; Sex: Female; individu... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476341 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0462.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 55; Sex: Male; individual... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476342 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0577.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 82; Sex: Female; individu... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476343 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1238.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 49; Sex: Female; individu... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476344 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1279.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 72; Sex: Male; individual... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476345 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0730.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 34; Sex: Female; individu... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476346 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1193.C1 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: before glucocorticoid treatment; age (years): 32; Sex: Male; individual... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476347 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1306.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 60; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476348 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0773.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 25; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476349 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0285.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 83; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476350 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0039.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 50; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476351 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1229.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 43; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476352 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0074.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 59; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476353 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1267.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 39; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476354 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1289.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 22; Sex: Male... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476355 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0168.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 46; Sex: Fema... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476356 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1359.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 37; Sex: Fema... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476357 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0714.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 26; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476358 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1213C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 28; Sex: F... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476359 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1106.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 26; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476360 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0462.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 55; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476361 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0577.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 82; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476362 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1238.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 49; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476363 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1279.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 72; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476364 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 0730.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 34; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476365 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1193.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 32; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

specimen_material plasma GSM3476366 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence plasma 1416.C2 plasma disease state: UC; corticosteroid response: Glucocorticoid non-responder; collection time: 3rd day after starting Glucocorticoid treatment; age (years): 30; Sex: ... controlled vocabulary controlled vocabulary specimen material match: plasma

tissue colon GSE122618 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence rectal dataset_accession: GSE122618 dataset_title: Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational s... controlled vocabulary controlled vocabulary tissue match: rectal

tissue intestine GSE122618 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence intestinal dataset_accession: GSE122618 dataset_title: Circulating miR 218-5p, alone or in combination, predicts corticosteroid failure in ulcerative colitis. Study through computational s... controlled vocabulary controlled vocabulary tissue match: intestinal

Sample Group Preview

46 rows shown Show Hide

Study totals: Case 46 | Control 0 | Unassigned 0 | Excluded 0 | Ambiguous 0 46 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Inflammatory bowel disease	Case	GSM3476321	VC1	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 56; Sex: Male; Individual: VC1; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476322	VC2	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 54; Sex: Female; Individual: VC2; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476323	VC5	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 68; Sex: Male; Individual: VC5; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476324	VC6	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 59; Sex: Female; Individual: VC6; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476325	VC8	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 56; Sex: Female; Individual: VC8; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476326	VC9	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 44; Sex: Female; Individual: VC9; Sample type: Plasma	Case marker detected.
Inflammatory bowel disease	Case	GSM3476327	VC11	Plasma Disease state: Reference; Corticosteroid response: No IBD treatment; Collection time: No IBD treatment; Age (years): 71; Sex: Female; Individual: VC11; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476328	0074.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 59; Sex: Male; Individual: 74; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476329	1359.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 37; Sex: Female; Individual: 1359; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476330	1267.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 39; Sex: Male; Individual: 1267; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476331	1289.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 22; Sex: Male; Individual: 1289; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476332	0168.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 46; Sex: Female; Individual: 168; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476333	1306.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 60; Sex: Male; Individual: 1306; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476334	0773.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 25; Sex: Male; Individual: 773; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476335	0039.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 50; Sex: Male; Individual: 39; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476336	1229.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 43; Sex: Male; Individual: 1229; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476337	0285.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: Before glucocorticoid treatment; Age (years): 83; Sex: Male; Individual: 285; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476338	0714.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 26; Sex: Male; Individual: 714; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476339	1213.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 28; Sex: Female; Individual: 1213; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476340	1106.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 26; Sex: Female; Individual: 1106; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476341	0462.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 55; Sex: Male; Individual: 462; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476342	0577.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 82; Sex: Female; Individual: 577; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476343	1238.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 49; Sex: Female; Individual: 1238; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476344	1279.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 72; Sex: Male; Individual: 1279; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476345	0730.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 34; Sex: Female; Individual: 730; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476346	1193.C1	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: Before glucocorticoid treatment; Age (years): 32; Sex: Male; Individual: 1193; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476347	1306.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 60; Sex: Male; Individual: 1306; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476348	0773.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 25; Sex: Male; Individual: 773; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476349	0285.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 83; Sex: Male; Individual: 285; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476350	0039.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 50; Sex: Male; Individual: 39; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476351	1229.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 43; Sex: Male; Individual: 1229; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476352	0074.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 59; Sex: Male; Individual: 74; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476353	1267.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 39; Sex: Male; Individual: 1267; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476354	1289.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 22; Sex: Male; Individual: 1289; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476355	0168.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 46; Sex: Female; Individual: 168; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476356	1359.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 37; Sex: Female; Individual: 1359; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476357	0714.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 26; Sex: Male; Individual: 714; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476358	1213C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 28; Sex: Female; Individual: 1213; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476359	1106.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 26; Sex: Female; Individual: 1106; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476360	0462.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 55; Sex: Male; Individual: 462; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476361	0577.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 82; Sex: Female; Individual: 577; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476362	1238.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 49; Sex: Female; Individual: 1238; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476363	1279.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 72; Sex: Male; Individual: 1279; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476364	0730.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 34; Sex: Female; Individual: 730; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476365	1193.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 32; Sex: Male; Individual: 1193; Sample type: Plasma	Case marker detected.
Ulcerative colitis	Case	GSM3476366	1416.C2	Plasma Disease state: UC; Corticosteroid response: Glucocorticoid non-responder; Collection time: 3rd day after starting Glucocorticoid treatment; Age (years): 30; Sex: Female; Individual: 1416; Sample type: Plasma	Case marker detected.

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External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.

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Use as Discovery Cohort