GSE137100

Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

12 case / 0 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: bulk RNA-seq
Organism: Mus musculus
Whole-study samples: 12 samples
Specimen: Tissue
Reported/interpreted study design: Unclear study design Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Qin S, Zhang D, Zhu J
Contact name: Jinhang Zhu
Submission date: 2019-09-09
Last update: 2021-06-28
Organization: Shanghai Jiao Tong University
Department: Not available
Public date: 2021-06-28
Experiment types: Non-coding RNA profiling by high throughput sequencing
Platforms: GPL13112 Illumina HiSeq 2000 (Mus musculus)
Series type: Series
SubSeries: Not available
BioProject: PRJNA564553

Summary

Pien Tze Huang (PZH) is herbal traditional Chinese medicine which was widely utilized in Asia for hepatic diseases. We constructed two groups hepatic fibrosis mice model using CCl4, one group using PZH treatment and another group replacing PZH with double distilled water. All 12 mice were fed for 8 weeks and then killed to have their liver tissue taken out. Small RNA-seq were used to identify miRNAs of PZH medicine effect for hepatic fibrosis. We found the expression of these miRNAs (mmu-miR-205-5p, mmu-miR-3064-5p, mmu-miR-205-5p, mmu-miR-370-3p, mmu-miR-665-3p) were changed in PZH medicine treatment for hepatic fibrosis study. Furthermore, Hmga2 and Fgf9, miRNAs corresponding target genes (Sp4, Slc2a6, Tln2, Hmga2, Ank3, Pax9, Fgf9), have been reported association with hepatic fibrosis.

Overall design

We constructed two groups hepatic fibrosis mice model using CCl4, one group using PZH treatment and another group replacing PZH with double distilled water. Small RNA-seq were used to identify miRNAs of PZH medicine effect for hepatic fibrosis.

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 12 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Planned source for curated expression experiment links.	No match found
PubMed	Publication context when PubMed identifiers are already known.	No match found

Metadata Quality Components

Persisted metadata quality

93 pts

Clarity: 93%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Only one side of the comparison is clearly grouped. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Not ready

55% DE readiness

Contrast completeness

10/25 pts

Only one side of the contrast is present; downstream DE needs both groups.

Minimum group size

0/20 pts

Minimum group size cannot be evaluated until a complete contrast exists.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

0/10 pts

Critical warnings must be resolved before downstream analysis.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No complete case/control contrast is available.
Critical dataset warnings must be resolved.
Secondary RNA assay context should be analyzed separately from ordinary bulk RNA-seq.

Next Steps

Resolve critical warnings before downstream analysis.

Analysis Preparation Checklist

4/6 ready

Group labels reviewed

Blocked

No complete case/control grouping exists yet.

Review the sample grouping table and assign both case and control groups.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Analysis readiness has blockers that must be resolved before DE.

Analysis preparation checklist contains blocked items.

No complete case/control or treatment/control contrast is available.

At least one comparison group has fewer than two samples.

Critical dataset warnings are present.

Assay context may require expert handling before DESeq2-style analysis.

Study design is model-system or unclear and should be reviewed before analysis.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Organism differs from search intent Mus musculus Search intent expects Homo sapiens. Organism came from Normalization rules.
Disease context Fibrosis, liver fibrosis Disease context came from Normalization rules.
Likely case group Liver fibrosis 12 samples
Likely control group No control group detected 0 samples

Intent Interpretation

Downgrade or exclusion reason Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Fibrosis, Liver fibrosis.
Processed data is available for downstream review.

Cautions

Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%.
Downgraded for tissue search because study design or specimen source is unclear.
Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Missing or unclear metadata. Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Small RNA, miRNA, circRNA, or extracellular-vesicle RNA context downgraded for primary mRNA tissue ranking.
Overall score capped because comparison suitability is weak for the selected search intent.
Overall score capped because non-human datasets are outside the selected human ranking intent.
Overall score capped because secondary RNA assays are not primary mRNA tissue RNA-seq.
Missing or unclear metadata. Comparison - Unclear study design. Specimen - Tissue. Comparison suitability: 0%.
Missing or unclear metadata. Downgraded for tissue search because study design or specimen source is unclear.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

No clear control group was detected from normalized metadata.
Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.
Dataset organism does not match the human patient-tissue tumor-normal intent.
Patient-tissue tumor-normal intent requires clear tumor-normal grouping.

Normalized Fields

53 fields

Field Value Source Derived by Confidence Evidence Reason

anatomical_source liver GSM4066924 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066925 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066926 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066927 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066928 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066929 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066930 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066931 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066932 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066933 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066934 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

anatomical_source liver GSM4066935 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence liver tissue: Liver sample-anatomical-source-v1 sample-local anatomical source

assay_type bulk RNA-seq GSE137100 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence bulk rna-seq dataset_accession: GSE137100 dataset_title: Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments organism: Mus musculus assay... keyword match keyword match: bulk rna-seq

disease fibrosis GSE137100 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis dataset_accession: GSE137100 dataset_title: Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments organism: Mus musculus assay... controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSE137100 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis dataset_accession: GSE137100 dataset_title: Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments organism: Mus musculus assay... controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066924 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066924 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066925 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066925 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066926 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066926 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066927 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066927 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066928 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066928 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066929 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis Control6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066929 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis Control6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066930 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066930 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066931 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066931 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066932 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066932 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066933 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066933 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066934 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066934 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

disease fibrosis GSM4066935 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence fibrosis Hepatic Fibrosis PZH6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: fibrosis

disease liver fibrosis GSM4066935 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence hepatic fibrosis Hepatic Fibrosis PZH6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary disease match: hepatic fibrosis

organism Mus musculus GSE137100 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence mus musculus dataset_accession: GSE137100 dataset_title: Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments organism: Mus musculus assay... keyword match keyword match: mus musculus

tissue liver GSE137100 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver dataset_accession: GSE137100 dataset_title: Identification of miRNAs as biomarkers of drug response of Pien Tze Huang in Hepatic Fibrosis Treatments organism: Mus musculus assay... controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066924 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066925 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066926 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066927 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066928 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066929 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis Control6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066930 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH1 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066931 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH2 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066932 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH3 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066933 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH4 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066934 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH5 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

tissue liver GSM4066935 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence liver Hepatic Fibrosis PZH6 hepatic fibrosis mice model strain: C57BL/6; tissue: Liver; cell type: hepatic fibrosis controlled vocabulary controlled vocabulary tissue match: liver

Sample Group Preview

12 rows shown Show Hide

Study totals: Case 12 | Control 0 | Unassigned 0 | Excluded 0 | Ambiguous 0 12 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Liver fibrosis	Case	GSM4066924	Hepatic Fibrosis Control1	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066925	Hepatic Fibrosis Control2	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066926	Hepatic Fibrosis Control3	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066927	Hepatic Fibrosis Control4	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066928	Hepatic Fibrosis Control5	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066929	Hepatic Fibrosis Control6	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066930	Hepatic Fibrosis PZH1	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066931	Hepatic Fibrosis PZH2	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066932	Hepatic Fibrosis PZH3	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066933	Hepatic Fibrosis PZH4	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066934	Hepatic Fibrosis PZH5	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.
Liver fibrosis	Case	GSM4066935	Hepatic Fibrosis PZH6	Hepatic fibrosis mice model Strain: C57BL/6; Tissue: Liver; Cell type: Hepatic fibrosis	Case marker detected.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.