GSE14580

Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

24 case / 6 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: microarray
Organism: Homo sapiens
Whole-study samples: 30 samples
Specimen: Biopsy
Reported/interpreted study design: Disease/model vs control Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Geboes K, Schuit F, Rutgeerts P
Contact name: Ingrid Arijs
Submission date: 2009-01-26
Last update: 2019-03-25
Organization: KULeuven
Department: Clinical and Experimental Medicine
Public date: 2010-01-07
Experiment types: Expression profiling by array
Platforms: GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Series type: Series
SubSeries: Not available
BioProject: PRJNA111695

Summary

Infliximab, an anti-TNF-alpha monoclonal antibody, is an effective treatment for ulcerative colitis (UC) with over 60% of patients responding to treatment and up to 30% reaching remission. The mechanism of resistance to anti-TNF-alpha is unknown. This study used colonic mucosal gene expression to provide a predictive response signature for infliximab treatment in UC. Keywords: drug response

Overall design

Twenty-four patients with active UC, refractory to corticosteroids and/or immunosuppression, underwent colonoscopy with biopsies from diseased colon within a week prior to the first intravenous infusion of 5 mg infliximab per kg body weight. Response to infliximab was defined as endoscopic and histologic healing at 4-6 weeks after first infliximab treatment. Six control patients with normal colonoscopy were included. Total RNA was isolated from colonic mucosal biopsies, labelled and hybridized to Affymetrix Human Genome U133 Plus 2.0 Arrays.

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 30 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Curated expression experiment linkage and source URL. Expression Atlas accession E-GEOD-14580	Available
PubMed	Primary GEO citations and related PubMed articles that mention this dataset. 7 linked publications 7 DOIs Primary publication Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis. Gut, 2009 PubMed DOI Related publications Management of ulcerative colitis by dichloroacetate: Impact on NFATC1/NLRP3/IL1B signaling based on bioinformatics analysis combined with in vivo experimental verification. Inflammopharmacology, 2024 PubMed DOI Identified potential biomarkers may predict primary nonresponse to infliximab in patients with ulcerative colitis. Autoimmunity, 2022 PubMed DOI SPP1 in infliximab resistant ulcerative colitis and associated colorectal cancer: an analysis of differentially expressed genes. European journal of gastroenterology & hepatology, 2022 PubMed DOI Tenascin-C Is Increased in Inflammatory Bowel Disease and Is Associated with response to Infliximab Therapy. BioMed research international, 2019 PubMed DOI Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis. Frontiers in immunology, 2023 PubMed DOI Identification of Specific Biomarkers and Pathways in the Treatment Response of Infliximab for Inflammatory Bowel Disease: In-Silico Analysis. Life (Basel, Switzerland), 2023 PubMed DOI	Available

Metadata Quality Components

Persisted metadata quality

100 pts

Clarity: 100%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review

97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
Disease context Ulcerative colitis Disease context came from Normalization rules.
Likely case group Ulcerative colitis 24 samples
Likely control group Control 6 samples

Intent Interpretation

Downgrade or exclusion reason Downgraded assay: microarray cohorts are separated from the RNA-seq intent. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

Comparison: Disease/model vs control. Specimen: Biopsy. Comparison suitability: 0%.
Interpreted disease metadata: Ulcerative colitis.
Processed data is available for downstream review.
External evidence: Expression Atlas curated experiment link is available.
External evidence: PubMed links 7 publications; 7 DOIs available: PMID 19700435, PMID 31886172, PMID 35102110, PMID 35876170, PMID 36983834.
Publication context: Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis.. Gut, 2009. PMID 19700435. DOI 10.1136/gut.2009.178665.
Publication context: Tenascin-C Is Increased in Inflammatory Bowel Disease and Is Associated with response to Infliximab Therapy.. BioMed research international, 2019. PMID 31886172. DOI 10.1155/2019/1475705.
Publication context: SPP1 in infliximab resistant ulcerative colitis and associated colorectal cancer: an analysis of differentially expressed genes.. European journal of gastroenterology & hepatology, 2022. PMID 35102110. DOI 10.1097/MEG.0000000000002349.
Publication context: 4 additional linked PubMed publications are available.

Cautions

Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
Microarray expression context downgraded below primary bulk RNA-seq for the default tissue ranking.
Overall score capped because comparison suitability is weak for the selected search intent.
Overall score capped because microarray cohorts should be compared separately from RNA-seq cohorts.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Microarray expression context was detected; compare separately from RNA-seq cohorts.
Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Normalized Fields

148 fields

Field Value Source Derived by Confidence Evidence Reason

anatomical_source colon GSM364627 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364628 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364629 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364630 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364631 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364632 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364633 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364634 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364635 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364636 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364637 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364638 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364639 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364640 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364641 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364642 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364643 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364644 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364645 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364646 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364647 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364648 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364649 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364650 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364651 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364652 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364653 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364654 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364655 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM364656 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon tissue: Colon sample-anatomical-source-v1 sample-local anatomical source

assay_type microarray GSE14580 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence microarray dataset_accession: GSE14580 dataset_title: Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis organism: Homo sapiens assay_type: micro... keyword match keyword match: microarray

collection_method biopsy GSM364627 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO1 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364628 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO2 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364629 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO3 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364630 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO4 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364631 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO5 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364632 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO6 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364633 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR1_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364634 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR2_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364635 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR3_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364636 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR4_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364637 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR5_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364638 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR6_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364639 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR7_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364640 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR8_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364641 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR1_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364642 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR2_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364643 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR3_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364644 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR4_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364645 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR5_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364646 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR6_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364647 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR7_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364648 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR8_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364649 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR9_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364650 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR10_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364651 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR11_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364652 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR12_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364653 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR13_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364654 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR14_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364655 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR15_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

collection_method biopsy GSM364656 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR16_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary collection method match: biopsy

disease ulcerative colitis GSE14580 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis dataset_accession: GSE14580 dataset_title: Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis organism: Homo sapiens assay_type: micro... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease ulcerative colitis GSM364633 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR1_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364634 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR2_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364635 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR3_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364636 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR4_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364637 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR5_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364638 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR6_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364639 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR7_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364640 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCR8_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364641 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR1_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364642 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR2_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364643 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR3_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364644 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR4_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364645 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR5_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364646 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR6_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364647 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR7_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364648 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR8_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364649 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR9_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364650 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR10_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364651 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR11_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364652 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR12_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364653 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR13_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364654 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR14_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364655 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR15_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

disease ulcerative colitis GSM364656 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence UC UCNR16_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary disease match: UC

organism Homo sapiens GSE14580 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence homo sapiens dataset_accession: GSE14580 dataset_title: Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis organism: Homo sapiens assay_type: micro... keyword match keyword match: homo sapiens

primary_tissue primary tissue GSM364627 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO1 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364628 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO2 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364629 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO3 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364630 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO4 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364631 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO5 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364632 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy CO6 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364633 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR1_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364634 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR2_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364635 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR3_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364636 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR4_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364637 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR5_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364638 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR6_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364639 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR7_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364640 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCR8_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364641 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR1_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364642 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR2_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364643 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR3_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364644 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR4_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364645 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR5_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364646 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR6_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364647 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR7_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364648 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR8_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364649 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR9_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364650 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR10_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364651 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR11_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364652 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR12_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364653 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR13_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364654 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR14_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364655 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR15_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

primary_tissue primary tissue GSM364656 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence biopsy UCNR16_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary primary tissue match: biopsy

tissue colon GSE14580 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon dataset_accession: GSE14580 dataset_title: Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis organism: Homo sapiens assay_type: micro... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364627 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO1 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364628 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO2 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364629 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO3 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364630 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO4 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364631 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO5 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364632 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CO6 Colonic mucosal biopsy from control individual tissue: Colon; disease: Control; response to infliximab: Not applicable; before or after first infliximab treatment: Not appli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364633 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR1_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364634 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR2_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364635 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR3_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364636 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR4_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364637 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR5_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364638 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR6_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364639 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR7_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364640 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCR8_beforeT Colonic mucosal biopsy from UC responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: Yes; before or after first infliximab... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364641 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR1_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364642 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR2_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364643 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR3_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364644 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR4_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364645 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR5_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364646 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR6_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364647 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR7_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364648 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR8_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364649 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR9_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first inflix... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364650 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR10_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364651 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR11_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364652 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR12_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364653 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR13_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364654 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR14_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364655 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR15_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM364656 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon UCNR16_beforeT Colonic mucosal biopsy from UC non-responder before first infliximab treatment tissue: Colon; disease: UC; response to infliximab: No; before or after first infli... controlled vocabulary controlled vocabulary tissue match: colon

Sample Group Preview

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Study totals: Case 24 | Control 6 | Unassigned 0 | Excluded 0 | Ambiguous 0 30 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Ulcerative colitis	Case	GSM364633	UCR1_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364634	UCR2_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364635	UCR3_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364636	UCR4_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364637	UCR5_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364638	UCR6_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364639	UCR7_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364640	UCR8_beforeT	Colonic mucosal biopsy from UC responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: Yes; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364641	UCNR1_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364642	UCNR2_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364643	UCNR3_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364644	UCNR4_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364645	UCNR5_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364646	UCNR6_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364647	UCNR7_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364648	UCNR8_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364649	UCNR9_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364650	UCNR10_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364651	UCNR11_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364652	UCNR12_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364653	UCNR13_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364654	UCNR14_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364655	UCNR15_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Ulcerative colitis	Case	GSM364656	UCNR16_beforeT	Colonic mucosal biopsy from UC non-responder before first infliximab treatment Tissue: Colon; Disease: UC; Response to infliximab: No; Before or after first infliximab treatment: Before first infliximab treatment	Case marker detected.
Control	Control	GSM364627	CO1	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.
Control	Control	GSM364628	CO2	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.
Control	Control	GSM364629	CO3	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.
Control	Control	GSM364630	CO4	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.
Control	Control	GSM364631	CO5	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.
Control	Control	GSM364632	CO6	Colonic mucosal biopsy from control individual Tissue: Colon; Disease: Control; Response to infliximab: Not applicable; Before or after first infliximab treatment: Not applicable	Sample-local control marker detected.

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External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.

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Use as Discovery Cohort