GSE156453

In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

26 case / 0 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: bulk RNA-seq
Organism: Homo sapiens
Whole-study samples: 33 samples
Specimen: Tissue
Reported/interpreted study design: Unclear study design Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Takayama K, Deguchi S, Ito K, Matsui A, Yamashita T, Kawakami K, Kishimoto W, Nakase H, Mizuguchi H
Contact name: Hiroyuki Mizuguchi
Submission date: 2020-08-19
Last update: 2023-03-01
Organization: Osaka University
Department: Graduate School of Pharmaceutical Sciences
Public date: 2021-04-30
Experiment types: Expression profiling by high throughput sequencing
Platforms: GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Series type: Series
SubSeries: Not available
BioProject: PRJNA658008

Summary

Orally administered drugs are absorbed and metabolized in the intestine. In order to accurately predict pharmacokinetics in the intestine, it is essential to understand the intestinal expression profiles of genes related to drug absorption, distribution, metabolism, and excretion (ADME). However, in many previous studies, gene expression analysis in the intestine has been carried out using specimens from cancer patients. In this study, in order to obtain a more accurate gene expression profile, biopsy samples were collected from 14 patients under endoscopic observation and RNA-seq analysis was performed. Gene expression analysis of drug metabolizing enzymes (CYPs), non-CYP enzymes, nuclear receptors, drug conjugating enzymes (UGTs and SULTs), and apical and basolateral drug transporters was performed in biopsy samples from the duodenum, ileum, colon, and rectum. The proportions of the CYPs expressed in the ileum were 25% (CYP3A4), 19% (CYP2C18), and 14% (CYP3A5). CYP3A4 and CYP2C19 were highly expressed in the duodenum and ileum, but not in the colon and rectum. In the ileum, apical transporters such as P-gp, PEPT1, BCRP, MRP2, and ASBT were strongly expressed, and the expression levels of P-gp and ASBT in the ileum were higher than those in other regions. In the ileum, basolateral transporters such as OSTα, OSTβ, and MRP3 were strongly expressed. Furthermore, we identified specific markers for the duodenum, ileum, colon, and rectum by conducting comprehensive gene expression analysis. We succeeded in obtaining gene expression profiles of drug ADME-related genes in vivo human intestinal epithelial cells. We expect that this information would be useful for accurate prediction of the pharmacokinetics of oral drugs.

Overall design

RNA expression profiles of Intestinal biopsy. iPS-derived enterocyte, Caco-2 cell and undifferentiated iPS-cells are used as reference control sample.

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 33 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Planned source for curated expression experiment links.	No match found
PubMed	Primary GEO citations and related PubMed articles that mention this dataset. 1 linked publication 1 DOI Primary publication In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics. Drug metabolism and disposition: the biological fate of chemicals, 2021 PubMed DOI	Available

Metadata Quality Components

Persisted metadata quality

93 pts

Clarity: 93%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Only one side of the comparison is clearly grouped. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Not ready

52% DE readiness

Contrast completeness

10/25 pts

Only one side of the contrast is present; downstream DE needs both groups.

Minimum group size

0/20 pts

Minimum group size cannot be evaluated until a complete contrast exists.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

12/15 pts

All non-excluded samples are assigned; excluded samples should still be confirmed.

Blocking warnings

0/10 pts

Critical warnings must be resolved before downstream analysis.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No complete case/control contrast is available.
Critical dataset warnings must be resolved.

Next Steps

Confirm excluded samples before creating the final analysis metadata file.
Resolve critical warnings before downstream analysis.

Analysis Preparation Checklist

3/6 ready

Group labels reviewed

Blocked

No complete case/control grouping exists yet.

Review the sample grouping table and assign both case and control groups.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Needs review

7 samples have hard exclusion flags in the proposed grouping.

Confirm excluded samples and preserve the reason in the analysis handoff.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Analysis readiness has blockers that must be resolved before DE.

Analysis preparation checklist contains blocked items.

No complete case/control or treatment/control contrast is available.

At least one comparison group has fewer than two samples.

Critical dataset warnings are present.

Study design is model-system or unclear and should be reviewed before analysis.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Disease context Crohn's disease, colorectal cancer, ulcerative colitis Disease context came from Normalization rules.
Likely case group Crohn's disease 26 samples
Likely control group No control group detected 0 samples

Intent Interpretation

Downgrade or exclusion reason Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Colorectal cancer, Crohn's disease, Ulcerative colitis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 33384384.
Publication context: In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics.. Drug metabolism and disposition: the biological fate of chemicals, 2021. PMID 33384384. DOI 10.1124/dmd.120.000283.

Cautions

Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%.
Downgraded for tissue search because study design or specimen source is unclear.
Excluded sample type flags reduce suitability.
Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Missing or unclear metadata. Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
Excluded model-system sample markers reduce suitability.
Overall score capped because comparison suitability is weak for the selected search intent.
Missing or unclear metadata. Comparison - Unclear study design. Specimen - Tissue. Comparison suitability: 0%.
Missing or unclear metadata. Downgraded for tissue search because study design or specimen source is unclear.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

No clear control group was detected from normalized metadata.
Multiple sample type labels or exclusion flags were detected.
Cell line samples appear to be included.
Patient-tissue tumor-normal intent requires clear tumor-normal grouping.

Normalized Fields

113 fields

Field Value Source Derived by Confidence Evidence Reason

anatomical_source ileum GSM4731834 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731835 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731836 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731837 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731838 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731839 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731840 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731841 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731842 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731843 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731844 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731845 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731846 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731847 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731848 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731849 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731850 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon source_name: Colon sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731851 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rectum source_name: Rectum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source colon GSM4731852 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rectum source_name: Rectum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731860 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

anatomical_source ileum GSM4731861 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ileum source_name: Ileum sample-anatomical-source-v1 sample-local anatomical source

assay_type bulk RNA-seq GSE156453 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence bulk rna-seq dataset_accession: GSE156453 dataset_title: In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics orga... keyword match keyword match: bulk rna-seq

disease Crohn's disease GSM4731830 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Duodenum-1 [TMG126_30_S37] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 53; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731830 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Duodenum-1 [TMG126_30_S37] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 53; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731831 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Duodenum-2 [TMG126_35_S41] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 42; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731831 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Duodenum-2 [TMG126_35_S41] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 42; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731832 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Duodenum-3 [TMG126_36_S42] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731832 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Duodenum-3 [TMG126_36_S42] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731833 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Duodenum-4 [TMG126_43_S46] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731833 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Duodenum-4 [TMG126_43_S46] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japa... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731834 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-1 [TMG126_28_S25] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731834 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-1 [TMG126_28_S25] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731835 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-2 [TMG126_31_S38] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731835 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-2 [TMG126_31_S38] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731836 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-3 [TMG126_37_S27] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731836 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-3 [TMG126_37_S27] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731837 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-4 [TMG126_40_S31] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731837 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-4 [TMG126_40_S31] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731838 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-5 [TMG126_45_S29] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731838 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-5 [TMG126_45_S29] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731839 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-6 [TMG126_47_S33] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731839 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-6 [TMG126_47_S33] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731840 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Ileum-7 [TMG126_49_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731840 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Ileum-7 [TMG126_49_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731841 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-1 [TMG126_29_S26] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731841 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-1 [TMG126_29_S26] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731842 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-2 [TMG126_32_S39] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731842 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-2 [TMG126_32_S39] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731843 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-3 [TMG126_33_S43] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731843 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-3 [TMG126_33_S43] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731844 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-4 [TMG126_34_S40] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 40; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731844 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-4 [TMG126_34_S40] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 40; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731845 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-5 [TMG126_38_S28] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731845 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-5 [TMG126_38_S28] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731846 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-6 [TMG126_41_S32] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731846 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-6 [TMG126_41_S32] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731847 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-7 [TMG126_44_S47] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 27; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731847 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-7 [TMG126_44_S47] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 27; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731848 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-8 [TMG126_46_S30] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731848 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-8 [TMG126_46_S30] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731849 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-9 [TMG126_48_S34] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731849 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-9 [TMG126_48_S34] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731850 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Colon-10 [TMG126_50_S36] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731850 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Colon-10 [TMG126_50_S36] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731851 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Rectum-1 [TMG126_39_S44] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731851 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Rectum-1 [TMG126_39_S44] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731852 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease Rectum-2 [TMG126_42_S45] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731852 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis Rectum-2 [TMG126_42_S45] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease colorectal cancer GSM4731853 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer Caco-2-1 [TMG126_51_S22] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary disease match: colon cancer

disease colorectal cancer GSM4731854 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer Caco-2-2 [TMG126_52_S23] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary disease match: colon cancer

disease colorectal cancer GSM4731855 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer Caco-2-3 [TMG126_53_S24] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary disease match: colon cancer

disease Crohn's disease GSM4731859 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease (repeated) Duodenum-2 [TMG126_1000035_S47] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 42; Sex: ... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731859 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis (repeated) Duodenum-2 [TMG126_1000035_S47] Duodenum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 42; Sex: ... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731860 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease (repeated) Ileum-5 [TMG126_1000045_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; ... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731860 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis (repeated) Ileum-5 [TMG126_1000045_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; ... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease Crohn's disease GSM4731861 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease (repeated) Ileum-7 [TMG126_1000049_S41] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM4731861 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis (repeated) Ileum-7 [TMG126_1000049_S41] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female... controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease colorectal cancer GSM4731862 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer (repeated) Caco-2-2 [TMG126_1000052_S29] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary disease match: colon cancer

excluded_sample_type cell line GSM4731853 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line Caco-2-1 [TMG126_51_S22] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731854 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line Caco-2-2 [TMG126_52_S23] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731855 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line Caco-2-3 [TMG126_53_S24] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731856 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line undifferentiated iPS cell-1 [TMG126_25_S6] iPS-cell (YOW) cell line: YOW; cell type: undifferentiated iPS-cells controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731857 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line undifferentiated iPS cell-2 [TMG126_26_S12] iPS-cell (YOW) cell line: YOW; cell type: undifferentiated iPS-cells controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731858 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line undifferentiated iPS cell-3 [TMG126_27_S18] iPS-cell (YOW) cell line: YOW; cell type: undifferentiated iPS-cells controlled vocabulary controlled vocabulary cell line match: cell line

excluded_sample_type cell line GSM4731862 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence cell line (repeated) Caco-2-2 [TMG126_1000052_S29] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary cell line match: cell line

organism Homo sapiens GSE156453 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence homo sapiens dataset_accession: GSE156453 dataset_title: In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics orga... keyword match keyword match: homo sapiens

tissue colon GSE156453 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon dataset_accession: GSE156453 dataset_title: In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics orga... controlled vocabulary controlled vocabulary tissue match: colon

tissue intestine GSE156453 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence intestine dataset_accession: GSE156453 dataset_title: In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics orga... controlled vocabulary controlled vocabulary tissue match: intestine

tissue intestine GSM4731834 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-1 [TMG126_28_S25] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731835 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-2 [TMG126_31_S38] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731836 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-3 [TMG126_37_S27] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731837 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-4 [TMG126_40_S31] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731838 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-5 [TMG126_45_S29] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731839 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-6 [TMG126_47_S33] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731840 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum Ileum-7 [TMG126_49_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary tissue match: ileum

tissue colon GSM4731841 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-1 [TMG126_29_S26] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 33; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731842 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-2 [TMG126_32_S39] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731843 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-3 [TMG126_33_S43] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 22; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731844 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-4 [TMG126_34_S40] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 40; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731845 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-5 [TMG126_38_S28] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731846 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-6 [TMG126_41_S32] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731847 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-7 [TMG126_44_S47] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 27; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731848 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-8 [TMG126_46_S30] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731849 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-9 [TMG126_48_S34] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 23; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731850 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Colon-10 [TMG126_50_S36] Colon disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female; race: Japanese controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731851 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence rectum Rectum-1 [TMG126_39_S44] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 54; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: rectum

tissue colon GSM4731852 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence rectum Rectum-2 [TMG126_42_S45] Rectum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 51; Sex: male; race: Japanese controlled vocabulary controlled vocabulary tissue match: rectum

tissue colon GSM4731853 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Caco-2-1 [TMG126_51_S22] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731854 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Caco-2-2 [TMG126_52_S23] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM4731855 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon Caco-2-3 [TMG126_53_S24] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary tissue match: colon

tissue intestine GSM4731860 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum (repeated) Ileum-5 [TMG126_1000045_S35] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 44; Sex: male; ... controlled vocabulary controlled vocabulary tissue match: ileum

tissue intestine GSM4731861 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ileum (repeated) Ileum-7 [TMG126_1000049_S41] Ileum disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); sampling region: non-inflammatory area; age (year): 29; Sex: female... controlled vocabulary controlled vocabulary tissue match: ileum

tissue colon GSM4731862 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon (repeated) Caco-2-2 [TMG126_1000052_S29] Caco-2 cell line: Caco-2; cell type: Colon-cancer cell line controlled vocabulary controlled vocabulary tissue match: colon

Sample Group Preview

33 rows shown Show Hide

Study totals: Case 26 | Control 0 | Unassigned 0 | Excluded 7 | Ambiguous 0 33 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Crohn's disease	Case	GSM4731830	Duodenum-1 [TMG126_30_S37]	Duodenum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 53; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731831	Duodenum-2 [TMG126_35_S41]	Duodenum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 42; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731832	Duodenum-3 [TMG126_36_S42]	Duodenum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 54; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731833	Duodenum-4 [TMG126_43_S46]	Duodenum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 51; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731834	Ileum-1 [TMG126_28_S25]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 33; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731835	Ileum-2 [TMG126_31_S38]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 54; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731836	Ileum-3 [TMG126_37_S27]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 54; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731837	Ileum-4 [TMG126_40_S31]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 51; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731838	Ileum-5 [TMG126_45_S29]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 44; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731839	Ileum-6 [TMG126_47_S33]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 23; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731840	Ileum-7 [TMG126_49_S35]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 29; Sex: Female; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731841	Colon-1 [TMG126_29_S26]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 33; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731842	Colon-2 [TMG126_32_S39]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 22; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731843	Colon-3 [TMG126_33_S43]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 22; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731844	Colon-4 [TMG126_34_S40]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 40; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731845	Colon-5 [TMG126_38_S28]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 54; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731846	Colon-6 [TMG126_41_S32]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 51; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731847	Colon-7 [TMG126_44_S47]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 27; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731848	Colon-8 [TMG126_46_S30]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 44; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731849	Colon-9 [TMG126_48_S34]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 23; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731850	Colon-10 [TMG126_50_S36]	Colon Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 29; Sex: Female; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731851	Rectum-1 [TMG126_39_S44]	Rectum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 54; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731852	Rectum-2 [TMG126_42_S45]	Rectum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 51; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731859	(Repeated) Duodenum-2 [TMG126_1000035_S47]	Duodenum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 42; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731860	(Repeated) Ileum-5 [TMG126_1000045_S35]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 44; Sex: Male; Race: Japanese	Case marker detected.
Crohn's disease	Case	GSM4731861	(Repeated) Ileum-7 [TMG126_1000049_S41]	Ileum Disease state: Crohn’s Disease (CD) or Ulcerative colitis (UC); Sampling region: Non-inflammatory area; Age (year): 29; Sex: Female; Race: Japanese	Case marker detected.
Excluded: Cell line	Excluded	GSM4731853	Caco-2-1 [TMG126_51_S22]	Caco-2 Cell line: Caco-2; Cell type: Colon-cancer cell line	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731854	Caco-2-2 [TMG126_52_S23]	Caco-2 Cell line: Caco-2; Cell type: Colon-cancer cell line	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731855	Caco-2-3 [TMG126_53_S24]	Caco-2 Cell line: Caco-2; Cell type: Colon-cancer cell line	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731856	Undifferentiated iPS cell-1 [TMG126_25_S6]	iPS-cell (YOW) Cell line: YOW; Cell type: Undifferentiated iPS-cells	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731857	Undifferentiated iPS cell-2 [TMG126_26_S12]	iPS-cell (YOW) Cell line: YOW; Cell type: Undifferentiated iPS-cells	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731858	Undifferentiated iPS cell-3 [TMG126_27_S18]	iPS-cell (YOW) Cell line: YOW; Cell type: Undifferentiated iPS-cells	cell line: Normalized exclusion flag detected: cell line.
Excluded: Cell line	Excluded	GSM4731862	(Repeated) Caco-2-2 [TMG126_1000052_S29]	Caco-2 Cell line: Caco-2; Cell type: Colon-cancer cell line	cell line: Normalized exclusion flag detected: cell line.

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External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.

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Sample Group Preview

Use as Discovery Cohort