GSE185263

Predicting sepsis severity at first clinical presentation: the role of endotypes and mechanistic signatures

Whole-study status Exploratory only

Dataset can inform exploration but is not strong enough for primary analysis.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source
GEO
Assay
bulk RNA-seq
Organism
Homo sapiens
Whole-study samples
392 samples
Specimen
Biofluid
Reported/interpreted study design
Patient biofluid vs healthy control Design classification does not establish patient pairs.
Comparison type
Tumor vs normal
Contributors
Baghela A, Hancock RE
Contact name
Robert EW Hancock
Submission date
2021-10-04
Last update
2023-05-12
Organization
University of British Columbia
Department
Microbiology and Immunology
Public date
2022-01-10
Experiment types
Expression profiling by high throughput sequencing
Platforms
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Series type
Series
SubSeries
Not available
BioProject
PRJNA768419

Summary

Identifying at first clinical presentation gene expression signatures that predict subsequent severity will allow clinicians to identify the most at risk groups of patients, and also enable appropriate antibiotic use. Accordingly, we characterized the blood immune profiles of patients with early/pre-sepsis to identify signatures reflecting disease severity, organ dysfunction, mortality, and specific endotypes/mechanisms.

Overall design

Whole blood RNA-seq and clinical data was collected from 348 patients from four emergency rooms and one intensive care unit.

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
392 GSM samples
 Primary source
recount3

Planned trusted source for processed count availability.

 No match found
Expression Atlas

Planned source for curated expression experiment links.

 No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

14 linked publications 13 DOIs

Primary publication

  1. Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures. EBioMedicine, 2022
  2. Predicting severity in COVID-19 disease using sepsis blood gene expression signatures. Scientific reports, 2023
  3. Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms. Frontiers in immunology, 2023

Related publications

  1. Identification of key genes and development of an identifying machine learning model for sepsis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2025
  2. The ferroptosis-related gene MAFG screened by machine learning is associated with the diagnosis and prognosis of sepsis. Clinical and experimental medicine, 2025
  3. Single-cell Sequence Analysis Combined with Multiple Machine Learning to Identify Markers in Sepsis Patients: LILRA5. Inflammation, 2023
  4. Identification of lethality-related m7G methylation modification patterns and the regulatory features of immune microenvironment in sepsis. Heliyon, 2025
  5. Alpha-1 antitrypsin targeted neutrophil elastase protects against sepsis-induced inflammation and coagulation in mice via inhibiting neutrophil extracellular trap formation. Life sciences, 2024
  6. Comprehensive multi-omics analysis reveals the core role of glycerophospholipid metabolism in the influence of short-chain fatty acids on the development of sepsis. Scientific reports, 2025
  7. Uncovering hub genes in sepsis through bioinformatics analysis. Medicine, 2023
  8. ACOD1 expression in patients with sepsis: an exploratory study of associations with disease severity and immune signatures. BMC infectious diseases, 2026
  9. Significant difference of differential expression pyroptosis-related genes and their correlations with infiltrated immune cells in sepsis. Frontiers in cellular and infection microbiology, 2022
  10. Identification of amino acid metabolism‑related genes as diagnostic and prognostic biomarkers in sepsis through machine learning. Experimental and therapeutic medicine, 2025
  11. Identification and Validation of Mitochondria-Related Genes for Diagnosis of Early-Stage Sepsis. Annals of clinical and laboratory science, 2025
Available

Metadata Quality Components

Persisted metadata quality

100 pts
Clarity
100%
Weight
100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review
100% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

10/10 pts

No dataset warnings are present.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

  • Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
  • Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Standard analyst review

Proceed only after the analyst confirms grouping, exclusions, and source files.

By Siftome standards, no expert review was triggered.

Why This Is Ranked Here

Tumor vs normal
Exploratory only Dataset can inform exploration but is not strong enough for primary analysis.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Disease context Sepsis Disease context came from Normalization rules.
  • Likely case group Sepsis 348 samples
  • Likely control group Healthy control 44 samples

Intent Interpretation

  • Downgrade or exclusion reason Downgraded for tissue search because it is a biofluid cohort. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Comparison: Patient biofluid vs healthy control. Specimen: Biofluid. Comparison suitability: 10%.
  • Prioritized assay: bulk RNA-seq is the active assay expectation.
  • Interpreted disease metadata: Sepsis.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 14 publications; 13 DOIs available: PMID 35027333, PMID 36250055, PMID 36690713, PMID 36920635, PMID 37090709.
  • Publication context: Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures.. EBioMedicine, 2022. PMID 35027333. DOI 10.1016/j.ebiom.2021.103776.
  • Publication context: Significant difference of differential expression pyroptosis-related genes and their correlations with infiltrated immune cells in sepsis.. Frontiers in cellular and infection microbiology, 2022. PMID 36250055. DOI 10.3389/fcimb.2022.1005392.
  • Publication context: Predicting severity in COVID-19 disease using sepsis blood gene expression signatures.. Scientific reports, 2023. PMID 36690713. DOI 10.1038/s41598-023-28259-y.
  • Publication context: 11 additional linked PubMed publications are available.

Cautions

  • Downgraded for tissue search because it is a biofluid cohort.
  • Blood, plasma, or serum cohort downgraded because this ranking targets tissue tumor-vs-normal comparisons.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

No dataset warnings

Normalized Fields

showing 500 of 1528 fields

Sample Group Preview

showing 94 of 392 preview rows Show Hide
Study totals: Case 348 | Control 44 | Unassigned 0 | Excluded 0 | Ambiguous 0 showing 94 of 392 preview rows
Group Role Accession Title Source / characteristics Reason
Sepsis Case GSM5608946 Sepcol001 Whole Blood Disease state: Sepsis; Age: 64; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 6; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608947 Sepcol002 Whole Blood Disease state: Sepsis; Age: 45; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 4; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608948 Sepcol003 Whole Blood Disease state: Sepsis; Age: 61; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608949 Sepcol004 Whole Blood Disease state: Sepsis; Age: 71; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608950 Sepcol005 Whole Blood Disease state: Sepsis; Age: 69; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608951 Sepcol006 Whole Blood Disease state: Sepsis; Age: 20; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608952 Sepcol007 Whole Blood Disease state: Sepsis; Age: 50; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608953 Sepcol008 Whole Blood Disease state: Sepsis; Age: 67; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608954 Sepcol009 Whole Blood Disease state: Sepsis; Age: 37; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608955 Sepcol010 Whole Blood Disease state: Sepsis; Age: 41; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608956 Sepcol012 Whole Blood Disease state: Sepsis; Age: 54; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608957 Sepcol014 Whole Blood Disease state: Sepsis; Age: 37; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 5; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608958 Sepcol015 Whole Blood Disease state: Sepsis; Age: 58; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608959 Sepcol016 Whole Blood Disease state: Sepsis; Age: 67; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 4; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608960 Sepcol017 Whole Blood Disease state: Sepsis; Age: 50; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608961 Sepcol018 Whole Blood Disease state: Sepsis; Age: 62; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608962 Sepcol019 Whole Blood Disease state: Sepsis; Age: 82; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608963 Sepcol020 Whole Blood Disease state: Sepsis; Age: 69; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608964 Sepcol021 Whole Blood Disease state: Sepsis; Age: 52; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 4; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608965 Sepcol022 Whole Blood Disease state: Sepsis; Age: 26; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608966 Sepcol024 Whole Blood Disease state: Sepsis; Age: 83; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608967 Sepcol025 Whole Blood Disease state: Sepsis; Age: 88; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608968 Sepcol026 Whole Blood Disease state: Sepsis; Age: 45; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608969 Sepcol027 Whole Blood Disease state: Sepsis; Age: 29; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608970 Sepcol028 Whole Blood Disease state: Sepsis; Age: 19; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608971 Sepcol032 Whole Blood Disease state: Sepsis; Age: 64; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608972 Sepcol034 Whole Blood Disease state: Sepsis; Age: 46; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608973 Sepcol040 Whole Blood Disease state: Sepsis; Age: 39; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608974 Sepcol044 Whole Blood Disease state: Sepsis; Age: 18; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608975 Sepcol045 Whole Blood Disease state: Sepsis; Age: 73; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608976 Sepcol046 Whole Blood Disease state: Sepsis; Age: 46; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608977 Sepcol049 Whole Blood Disease state: Sepsis; Age: 74; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608978 Sepcol050 Whole Blood Disease state: Sepsis; Age: 78; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608979 Sepcol055 Whole Blood Disease state: Sepsis; Age: 20; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608980 Sepcol056 Whole Blood Disease state: Sepsis; Age: 18; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608981 Sepcol058 Whole Blood Disease state: Sepsis; Age: 87; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608982 Sepcol059 Whole Blood Disease state: Sepsis; Age: 39; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 6; In hospital mortality: NA; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608983 Sepcol060 Whole Blood Disease state: Sepsis; Age: 37; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Died; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608984 Sepcol061 Whole Blood Disease state: Sepsis; Age: 25; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 1; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608985 Sepcol062 Whole Blood Disease state: Sepsis; Age: 36; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608986 Sepcol063 Whole Blood Disease state: Sepsis; Age: 25; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608987 Sepcol064 Whole Blood Disease state: Sepsis; Age: 18; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 4; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608988 Sepcol065 Whole Blood Disease state: Sepsis; Age: 18; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 5; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608989 Sepcol067 Whole Blood Disease state: Sepsis; Age: 57; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608990 Sepcol069 Whole Blood Disease state: Sepsis; Age: 19; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 6; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608991 Sepcol070 Whole Blood Disease state: Sepsis; Age: 24; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608992 Sepcol071 Whole Blood Disease state: Sepsis; Age: 57; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608993 Sepcol073 Whole Blood Disease state: Sepsis; Age: 23; Sex: M; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 3; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608994 Sepcol075 Whole Blood Disease state: Sepsis; Age: 21; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 0; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
Sepsis Case GSM5608995 Sepcol077 Whole Blood Disease state: Sepsis; Age: 57; Sex: F; Collection location: Colombia; Collection site: Emergency Room; Sofa 24h post admisssion: 2; In hospital mortality: Survived; Tissue: Whole Blood Case marker detected.
298 additional case samples are hidden from this preview.
Healthy control Control GSM5609212 Hccol001 Whole Blood Disease state: Healthy; Age: 54; Sex: M; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609213 Hccol002 Whole Blood Disease state: Healthy; Age: 49; Sex: M; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609214 Hccol003 Whole Blood Disease state: Healthy; Age: 26; Sex: F; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609215 Hccol004 Whole Blood Disease state: Healthy; Age: 27; Sex: M; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609216 Hccol005 Whole Blood Disease state: Healthy; Age: 28; Sex: M; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609217 Hccol006 Whole Blood Disease state: Healthy; Age: 26; Sex: M; Collection location: Colombia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609218 HchlD072 Whole Blood Disease state: Healthy; Age: 56; Sex: F; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609219 HchlD149 Whole Blood Disease state: Healthy; Age: 35; Sex: F; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609220 HchlD188 Whole Blood Disease state: Healthy; Age: 25; Sex: M; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609221 HchlD201 Whole Blood Disease state: Healthy; Age: 29; Sex: M; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609222 Hcwes025 Whole Blood Disease state: Healthy; Age: 58; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609223 Hcwes027 Whole Blood Disease state: Healthy; Age: 57; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609224 Hcwes036 Whole Blood Disease state: Healthy; Age: 57; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609225 Hcwes037 Whole Blood Disease state: Healthy; Age: 59; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609226 Hcwes038 Whole Blood Disease state: Healthy; Age: 37; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609227 Hcwes039 Whole Blood Disease state: Healthy; Age: 57; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609228 Hcwes040 Whole Blood Disease state: Healthy; Age: 51; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609229 Hcwes050 Whole Blood Disease state: Healthy; Age: 29; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609230 Hcwes051 Whole Blood Disease state: Healthy; Age: 34; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609231 Hcwes054 Whole Blood Disease state: Healthy; Age: 57; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609232 Hcwes055 Whole Blood Disease state: Healthy; Age: 50; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609233 Hcwes056 Whole Blood Disease state: Healthy; Age: 44; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609234 Hcwes058 Whole Blood Disease state: Healthy; Age: 80; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609235 Hcwes059 Whole Blood Disease state: Healthy; Age: 53; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609236 Hcwes060 Whole Blood Disease state: Healthy; Age: 61; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609237 Hcwes062 Whole Blood Disease state: Healthy; Age: 64; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609238 Hcwes063 Whole Blood Disease state: Healthy; Age: 51; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609239 Hcwes064 Whole Blood Disease state: Healthy; Age: 59; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609240 Hcwes066 Whole Blood Disease state: Healthy; Age: 35; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609241 Hcwes067 Whole Blood Disease state: Healthy; Age: 39; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609242 Hcwes072 Whole Blood Disease state: Healthy; Age: 26; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609243 Hcwes074 Whole Blood Disease state: Healthy; Age: 59; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609244 Hcwes075 Whole Blood Disease state: Healthy; Age: 59; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609245 Hcwes078 Whole Blood Disease state: Healthy; Age: 23; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609246 Hcwimr093 Whole Blood Disease state: Healthy; Age: 62; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609247 Hcwimr094 Whole Blood Disease state: Healthy; Age: 62; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609248 Hcwimr095 Whole Blood Disease state: Healthy; Age: 68; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609249 Hcwimr096 Whole Blood Disease state: Healthy; Age: 72; Sex: M; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609250 Hcwimr097 Whole Blood Disease state: Healthy; Age: 63; Sex: F; Collection location: Australia; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609333 HchlD044 Whole Blood Disease state: Healthy; Age: 60; Sex: M; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609334 HchlD187 Whole Blood Disease state: Healthy; Age: 29; Sex: F; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609335 HchlD204 Whole Blood Disease state: Healthy; Age: 24; Sex: M; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609336 HchlD218 Whole Blood Disease state: Healthy; Age: 20; Sex: F; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.
Healthy control Control GSM5609337 HchlD219 Whole Blood Disease state: Healthy; Age: 27; Sex: M; Collection location: Vancouver; Collection site: Healthy/Pre-surgical; Sofa 24h post admisssion: NA; In hospital mortality: NA; Tissue: Whole Blood Sample-local control marker detected.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.