Matching samples

GSE186963 · Whole blood gene expression from infliximab treated Crohn's disease patients at three time points: pre-treatment, two weeks and fourteen weeks post first treatment

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (0)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

No uncertain samples.

Excluded samples (72)

GSM5664373

Excluded

HR_38_V1

Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Does not meet requirement
        • The reported value differs from the selected requirement.
        • HR_38_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: Baseline; crp: 2.1
      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
        • Supported by the indexed evidence.
        • specimen category excludes: Biofluid — Does not meet requirement
          • The reported value differs from the selected requirement.
          • HR_38_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: Baseline; crp: 2.1
        Source metadata
        Source name
        Whole blood
        Characteristics
        disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: Baseline; crp: 2.1
        Description
        Not reported
        Indexed organism evidence
        INFERRED · PARENT_INHERITED: Not reported
        Indexed assay evidence
        INFERRED · PARENT_INHERITED: Not reported
        Source
        GEO
        Original indexed metadata
        sample_accession: GSM5664373
sample_title: HR_38_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: Baseline; crp: 2.1

        GSM5664374

        Excluded

        HR_38_V2

        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

        Requirements and decision evidence
        • organism: Homo sapiens — Insufficient evidence
          • The required value is not reported.
          • assay type: bulk RNA-seq — Insufficient evidence
            • The required value is not reported.
            • specimen category: Tissue or biopsy — Does not meet requirement
              • The reported value differs from the selected requirement.
              • HR_38_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W2; crp: 1.2
            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
              • Supported by the indexed evidence.
              • specimen category excludes: Biofluid — Does not meet requirement
                • The reported value differs from the selected requirement.
                • HR_38_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W2; crp: 1.2
              Source metadata
              Source name
              Whole blood
              Characteristics
              disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W2; crp: 1.2
              Description
              Not reported
              Indexed organism evidence
              INFERRED · PARENT_INHERITED: Not reported
              Indexed assay evidence
              INFERRED · PARENT_INHERITED: Not reported
              Source
              GEO
              Original indexed metadata
              sample_accession: GSM5664374
sample_title: HR_38_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W2; crp: 1.2

              GSM5664375

              Excluded

              HR_38_V3

              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

              Requirements and decision evidence
              • organism: Homo sapiens — Insufficient evidence
                • The required value is not reported.
                • assay type: bulk RNA-seq — Insufficient evidence
                  • The required value is not reported.
                  • specimen category: Tissue or biopsy — Does not meet requirement
                    • The reported value differs from the selected requirement.
                    • HR_38_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W14; crp: 2
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Does not meet requirement
                      • The reported value differs from the selected requirement.
                      • HR_38_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W14; crp: 2
                    Source metadata
                    Source name
                    Whole blood
                    Characteristics
                    disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W14; crp: 2
                    Description
                    Not reported
                    Indexed organism evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Indexed assay evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Source
                    GEO
                    Original indexed metadata
                    sample_accession: GSM5664375
sample_title: HR_38_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-38; response status: Non-responder; visit: W14; crp: 2

                    GSM5664376

                    Excluded

                    HR_39_V1

                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                    Requirements and decision evidence
                    • organism: Homo sapiens — Insufficient evidence
                      • The required value is not reported.
                      • assay type: bulk RNA-seq — Insufficient evidence
                        • The required value is not reported.
                        • specimen category: Tissue or biopsy — Does not meet requirement
                          • The reported value differs from the selected requirement.
                          • HR_39_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: Baseline; crp: 2.6
                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                          • Supported by the indexed evidence.
                          • specimen category excludes: Biofluid — Does not meet requirement
                            • The reported value differs from the selected requirement.
                            • HR_39_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: Baseline; crp: 2.6
                          Source metadata
                          Source name
                          Whole blood
                          Characteristics
                          disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: Baseline; crp: 2.6
                          Description
                          Not reported
                          Indexed organism evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Indexed assay evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Source
                          GEO
                          Original indexed metadata
                          sample_accession: GSM5664376
sample_title: HR_39_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: Baseline; crp: 2.6

                          GSM5664377

                          Excluded

                          HR_39_V2

                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                          Requirements and decision evidence
                          • organism: Homo sapiens — Insufficient evidence
                            • The required value is not reported.
                            • assay type: bulk RNA-seq — Insufficient evidence
                              • The required value is not reported.
                              • specimen category: Tissue or biopsy — Does not meet requirement
                                • The reported value differs from the selected requirement.
                                • HR_39_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W2; crp: 0.1
                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                • Supported by the indexed evidence.
                                • specimen category excludes: Biofluid — Does not meet requirement
                                  • The reported value differs from the selected requirement.
                                  • HR_39_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W2; crp: 0.1
                                Source metadata
                                Source name
                                Whole blood
                                Characteristics
                                disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W2; crp: 0.1
                                Description
                                Not reported
                                Indexed organism evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Indexed assay evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Source
                                GEO
                                Original indexed metadata
                                sample_accession: GSM5664377
sample_title: HR_39_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W2; crp: 0.1

                                GSM5664378

                                Excluded

                                HR_39_V3

                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                Requirements and decision evidence
                                • organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                      • The reported value differs from the selected requirement.
                                      • HR_39_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W14; crp: 0.4
                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                      • Supported by the indexed evidence.
                                      • specimen category excludes: Biofluid — Does not meet requirement
                                        • The reported value differs from the selected requirement.
                                        • HR_39_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W14; crp: 0.4
                                      Source metadata
                                      Source name
                                      Whole blood
                                      Characteristics
                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W14; crp: 0.4
                                      Description
                                      Not reported
                                      Indexed organism evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Indexed assay evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Source
                                      GEO
                                      Original indexed metadata
                                      sample_accession: GSM5664378
sample_title: HR_39_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-39; response status: Responder; visit: W14; crp: 0.4

                                      GSM5664379

                                      Excluded

                                      HR_40_V1

                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                      Requirements and decision evidence
                                      • organism: Homo sapiens — Insufficient evidence
                                        • The required value is not reported.
                                        • assay type: bulk RNA-seq — Insufficient evidence
                                          • The required value is not reported.
                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                            • The reported value differs from the selected requirement.
                                            • HR_40_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: Baseline; crp: 1
                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                            • Supported by the indexed evidence.
                                            • specimen category excludes: Biofluid — Does not meet requirement
                                              • The reported value differs from the selected requirement.
                                              • HR_40_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: Baseline; crp: 1
                                            Source metadata
                                            Source name
                                            Whole blood
                                            Characteristics
                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: Baseline; crp: 1
                                            Description
                                            Not reported
                                            Indexed organism evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Indexed assay evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Source
                                            GEO
                                            Original indexed metadata
                                            sample_accession: GSM5664379
sample_title: HR_40_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: Baseline; crp: 1

                                            GSM5664380

                                            Excluded

                                            HR_40_V2

                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                            Requirements and decision evidence
                                            • organism: Homo sapiens — Insufficient evidence
                                              • The required value is not reported.
                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                • The required value is not reported.
                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                  • The reported value differs from the selected requirement.
                                                  • HR_40_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W2; crp: 1.1
                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                    • The reported value differs from the selected requirement.
                                                    • HR_40_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W2; crp: 1.1
                                                  Source metadata
                                                  Source name
                                                  Whole blood
                                                  Characteristics
                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W2; crp: 1.1
                                                  Description
                                                  Not reported
                                                  Indexed organism evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Indexed assay evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Source
                                                  GEO
                                                  Original indexed metadata
                                                  sample_accession: GSM5664380
sample_title: HR_40_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W2; crp: 1.1

                                                  GSM5664381

                                                  Excluded

                                                  HR_40_V3

                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                  Requirements and decision evidence
                                                  • organism: Homo sapiens — Insufficient evidence
                                                    • The required value is not reported.
                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                      • The required value is not reported.
                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                        • The reported value differs from the selected requirement.
                                                        • HR_40_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W14; crp: 2.67
                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                        • Supported by the indexed evidence.
                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                          • The reported value differs from the selected requirement.
                                                          • HR_40_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W14; crp: 2.67
                                                        Source metadata
                                                        Source name
                                                        Whole blood
                                                        Characteristics
                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W14; crp: 2.67
                                                        Description
                                                        Not reported
                                                        Indexed organism evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Indexed assay evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Source
                                                        GEO
                                                        Original indexed metadata
                                                        sample_accession: GSM5664381
sample_title: HR_40_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-40; response status: Responder; visit: W14; crp: 2.67

                                                        GSM5664382

                                                        Excluded

                                                        HR_42_V1

                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                        Requirements and decision evidence
                                                        • organism: Homo sapiens — Insufficient evidence
                                                          • The required value is not reported.
                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                            • The required value is not reported.
                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                              • The reported value differs from the selected requirement.
                                                              • HR_42_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: Baseline; crp: 3.4
                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                • The reported value differs from the selected requirement.
                                                                • HR_42_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: Baseline; crp: 3.4
                                                              Source metadata
                                                              Source name
                                                              Whole blood
                                                              Characteristics
                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: Baseline; crp: 3.4
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM5664382
sample_title: HR_42_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: Baseline; crp: 3.4

                                                              GSM5664383

                                                              Excluded

                                                              HR_42_V2

                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                              Requirements and decision evidence
                                                              • organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                    • The reported value differs from the selected requirement.
                                                                    • HR_42_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W2; crp: 0.9
                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                    • Supported by the indexed evidence.
                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                      • The reported value differs from the selected requirement.
                                                                      • HR_42_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W2; crp: 0.9
                                                                    Source metadata
                                                                    Source name
                                                                    Whole blood
                                                                    Characteristics
                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W2; crp: 0.9
                                                                    Description
                                                                    Not reported
                                                                    Indexed organism evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Indexed assay evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Source
                                                                    GEO
                                                                    Original indexed metadata
                                                                    sample_accession: GSM5664383
sample_title: HR_42_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W2; crp: 0.9

                                                                    GSM5664384

                                                                    Excluded

                                                                    HR_42_V3

                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                    Requirements and decision evidence
                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                      • The required value is not reported.
                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                        • The required value is not reported.
                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                          • The reported value differs from the selected requirement.
                                                                          • HR_42_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W14; crp: 0.48
                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                          • Supported by the indexed evidence.
                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                            • The reported value differs from the selected requirement.
                                                                            • HR_42_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W14; crp: 0.48
                                                                          Source metadata
                                                                          Source name
                                                                          Whole blood
                                                                          Characteristics
                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W14; crp: 0.48
                                                                          Description
                                                                          Not reported
                                                                          Indexed organism evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Indexed assay evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Source
                                                                          GEO
                                                                          Original indexed metadata
                                                                          sample_accession: GSM5664384
sample_title: HR_42_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-42; response status: Responder; visit: W14; crp: 0.48

                                                                          GSM5664385

                                                                          Excluded

                                                                          HR_44_V1

                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                          Requirements and decision evidence
                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                • The reported value differs from the selected requirement.
                                                                                • HR_44_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: Baseline; crp: 19.6
                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                  • The reported value differs from the selected requirement.
                                                                                  • HR_44_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: Baseline; crp: 19.6
                                                                                Source metadata
                                                                                Source name
                                                                                Whole blood
                                                                                Characteristics
                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: Baseline; crp: 19.6
                                                                                Description
                                                                                Not reported
                                                                                Indexed organism evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Indexed assay evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Source
                                                                                GEO
                                                                                Original indexed metadata
                                                                                sample_accession: GSM5664385
sample_title: HR_44_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: Baseline; crp: 19.6

                                                                                GSM5664386

                                                                                Excluded

                                                                                HR_44_V2

                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                Requirements and decision evidence
                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                  • The required value is not reported.
                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                      • The reported value differs from the selected requirement.
                                                                                      • HR_44_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W2; crp: 2.1
                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                      • Supported by the indexed evidence.
                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                        • The reported value differs from the selected requirement.
                                                                                        • HR_44_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W2; crp: 2.1
                                                                                      Source metadata
                                                                                      Source name
                                                                                      Whole blood
                                                                                      Characteristics
                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W2; crp: 2.1
                                                                                      Description
                                                                                      Not reported
                                                                                      Indexed organism evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Indexed assay evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Source
                                                                                      GEO
                                                                                      Original indexed metadata
                                                                                      sample_accession: GSM5664386
sample_title: HR_44_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W2; crp: 2.1

                                                                                      GSM5664387

                                                                                      Excluded

                                                                                      HR_44_V3

                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                      Requirements and decision evidence
                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                          • The required value is not reported.
                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                            • The reported value differs from the selected requirement.
                                                                                            • HR_44_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W14; crp: 1.19
                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                              • The reported value differs from the selected requirement.
                                                                                              • HR_44_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W14; crp: 1.19
                                                                                            Source metadata
                                                                                            Source name
                                                                                            Whole blood
                                                                                            Characteristics
                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W14; crp: 1.19
                                                                                            Description
                                                                                            Not reported
                                                                                            Indexed organism evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Indexed assay evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Source
                                                                                            GEO
                                                                                            Original indexed metadata
                                                                                            sample_accession: GSM5664387
sample_title: HR_44_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-44; response status: Responder; visit: W14; crp: 1.19

                                                                                            GSM5664388

                                                                                            Excluded

                                                                                            HR_46_V1

                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                            Requirements and decision evidence
                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                  • The reported value differs from the selected requirement.
                                                                                                  • HR_46_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: Baseline; crp: 6.8
                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                  • Supported by the indexed evidence.
                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                    • The reported value differs from the selected requirement.
                                                                                                    • HR_46_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: Baseline; crp: 6.8
                                                                                                  Source metadata
                                                                                                  Source name
                                                                                                  Whole blood
                                                                                                  Characteristics
                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: Baseline; crp: 6.8
                                                                                                  Description
                                                                                                  Not reported
                                                                                                  Indexed organism evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Indexed assay evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Source
                                                                                                  GEO
                                                                                                  Original indexed metadata
                                                                                                  sample_accession: GSM5664388
sample_title: HR_46_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: Baseline; crp: 6.8

                                                                                                  GSM5664389

                                                                                                  Excluded

                                                                                                  HR_46_V2

                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                  Requirements and decision evidence
                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                    • The required value is not reported.
                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                      • The required value is not reported.
                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                        • The reported value differs from the selected requirement.
                                                                                                        • HR_46_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W2; crp: 3.22
                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                        • Supported by the indexed evidence.
                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                          • The reported value differs from the selected requirement.
                                                                                                          • HR_46_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W2; crp: 3.22
                                                                                                        Source metadata
                                                                                                        Source name
                                                                                                        Whole blood
                                                                                                        Characteristics
                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W2; crp: 3.22
                                                                                                        Description
                                                                                                        Not reported
                                                                                                        Indexed organism evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Indexed assay evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Source
                                                                                                        GEO
                                                                                                        Original indexed metadata
                                                                                                        sample_accession: GSM5664389
sample_title: HR_46_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W2; crp: 3.22

                                                                                                        GSM5664390

                                                                                                        Excluded

                                                                                                        HR_46_V3

                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                        Requirements and decision evidence
                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                              • The reported value differs from the selected requirement.
                                                                                                              • HR_46_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W14; crp: 3
                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                • HR_46_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W14; crp: 3
                                                                                                              Source metadata
                                                                                                              Source name
                                                                                                              Whole blood
                                                                                                              Characteristics
                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W14; crp: 3
                                                                                                              Description
                                                                                                              Not reported
                                                                                                              Indexed organism evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Indexed assay evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Source
                                                                                                              GEO
                                                                                                              Original indexed metadata
                                                                                                              sample_accession: GSM5664390
sample_title: HR_46_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-46; response status: Responder; visit: W14; crp: 3

                                                                                                              GSM5664391

                                                                                                              Excluded

                                                                                                              HR_47_V1

                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                              Requirements and decision evidence
                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                • The required value is not reported.
                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                    • HR_47_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: Baseline; crp: 125.7
                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                    • Supported by the indexed evidence.
                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                      • HR_47_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: Baseline; crp: 125.7
                                                                                                                    Source metadata
                                                                                                                    Source name
                                                                                                                    Whole blood
                                                                                                                    Characteristics
                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: Baseline; crp: 125.7
                                                                                                                    Description
                                                                                                                    Not reported
                                                                                                                    Indexed organism evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Indexed assay evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Source
                                                                                                                    GEO
                                                                                                                    Original indexed metadata
                                                                                                                    sample_accession: GSM5664391
sample_title: HR_47_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: Baseline; crp: 125.7

                                                                                                                    GSM5664392

                                                                                                                    Excluded

                                                                                                                    HR_47_V2

                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                    Requirements and decision evidence
                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                        • The required value is not reported.
                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                          • HR_47_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W2; crp: 2.7
                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                            • HR_47_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W2; crp: 2.7
                                                                                                                          Source metadata
                                                                                                                          Source name
                                                                                                                          Whole blood
                                                                                                                          Characteristics
                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W2; crp: 2.7
                                                                                                                          Description
                                                                                                                          Not reported
                                                                                                                          Indexed organism evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Indexed assay evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Source
                                                                                                                          GEO
                                                                                                                          Original indexed metadata
                                                                                                                          sample_accession: GSM5664392
sample_title: HR_47_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W2; crp: 2.7

                                                                                                                          GSM5664393

                                                                                                                          Excluded

                                                                                                                          HR_47_V3

                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                          Requirements and decision evidence
                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                • HR_47_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W14; crp: 24.2
                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                  • HR_47_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W14; crp: 24.2
                                                                                                                                Source metadata
                                                                                                                                Source name
                                                                                                                                Whole blood
                                                                                                                                Characteristics
                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W14; crp: 24.2
                                                                                                                                Description
                                                                                                                                Not reported
                                                                                                                                Indexed organism evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Indexed assay evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Source
                                                                                                                                GEO
                                                                                                                                Original indexed metadata
                                                                                                                                sample_accession: GSM5664393
sample_title: HR_47_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-47; response status: Responder; visit: W14; crp: 24.2

                                                                                                                                GSM5664394

                                                                                                                                Excluded

                                                                                                                                HR_48_V1

                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                Requirements and decision evidence
                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                  • The required value is not reported.
                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                    • The required value is not reported.
                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                      • HR_48_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: Baseline; crp: 1.8
                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                        • HR_48_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: Baseline; crp: 1.8
                                                                                                                                      Source metadata
                                                                                                                                      Source name
                                                                                                                                      Whole blood
                                                                                                                                      Characteristics
                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: Baseline; crp: 1.8
                                                                                                                                      Description
                                                                                                                                      Not reported
                                                                                                                                      Indexed organism evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Indexed assay evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Source
                                                                                                                                      GEO
                                                                                                                                      Original indexed metadata
                                                                                                                                      sample_accession: GSM5664394
sample_title: HR_48_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: Baseline; crp: 1.8

                                                                                                                                      GSM5664395

                                                                                                                                      Excluded

                                                                                                                                      HR_48_V2

                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                      Requirements and decision evidence
                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                            • HR_48_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W2; crp: 0.8
                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                              • HR_48_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W2; crp: 0.8
                                                                                                                                            Source metadata
                                                                                                                                            Source name
                                                                                                                                            Whole blood
                                                                                                                                            Characteristics
                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W2; crp: 0.8
                                                                                                                                            Description
                                                                                                                                            Not reported
                                                                                                                                            Indexed organism evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Indexed assay evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Source
                                                                                                                                            GEO
                                                                                                                                            Original indexed metadata
                                                                                                                                            sample_accession: GSM5664395
sample_title: HR_48_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W2; crp: 0.8

                                                                                                                                            GSM5664396

                                                                                                                                            Excluded

                                                                                                                                            HR_48_V3

                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                            Requirements and decision evidence
                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                              • The required value is not reported.
                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                  • HR_48_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W14; crp: 1
                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                    • HR_48_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W14; crp: 1
                                                                                                                                                  Source metadata
                                                                                                                                                  Source name
                                                                                                                                                  Whole blood
                                                                                                                                                  Characteristics
                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W14; crp: 1
                                                                                                                                                  Description
                                                                                                                                                  Not reported
                                                                                                                                                  Indexed organism evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Indexed assay evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Source
                                                                                                                                                  GEO
                                                                                                                                                  Original indexed metadata
                                                                                                                                                  sample_accession: GSM5664396
sample_title: HR_48_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-48; response status: Responder; visit: W14; crp: 1

                                                                                                                                                  GSM5664397

                                                                                                                                                  Excluded

                                                                                                                                                  HR_29_V1

                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                      • The required value is not reported.
                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                        • HR_29_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: Baseline; crp: 4.9
                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                          • HR_29_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: Baseline; crp: 4.9
                                                                                                                                                        Source metadata
                                                                                                                                                        Source name
                                                                                                                                                        Whole blood
                                                                                                                                                        Characteristics
                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: Baseline; crp: 4.9
                                                                                                                                                        Description
                                                                                                                                                        Not reported
                                                                                                                                                        Indexed organism evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Indexed assay evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Source
                                                                                                                                                        GEO
                                                                                                                                                        Original indexed metadata
                                                                                                                                                        sample_accession: GSM5664397
sample_title: HR_29_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: Baseline; crp: 4.9

                                                                                                                                                        GSM5664398

                                                                                                                                                        Excluded

                                                                                                                                                        HR_29_V2

                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                              • HR_29_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                • HR_29_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                              Source metadata
                                                                                                                                                              Source name
                                                                                                                                                              Whole blood
                                                                                                                                                              Characteristics
                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                              Description
                                                                                                                                                              Not reported
                                                                                                                                                              Indexed organism evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Indexed assay evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Source
                                                                                                                                                              GEO
                                                                                                                                                              Original indexed metadata
                                                                                                                                                              sample_accession: GSM5664398
sample_title: HR_29_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W2; crp: 2.5

                                                                                                                                                              GSM5664399

                                                                                                                                                              Excluded

                                                                                                                                                              HR_29_V3

                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                    • HR_29_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W14; crp: 1.15
                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                      • HR_29_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W14; crp: 1.15
                                                                                                                                                                    Source metadata
                                                                                                                                                                    Source name
                                                                                                                                                                    Whole blood
                                                                                                                                                                    Characteristics
                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W14; crp: 1.15
                                                                                                                                                                    Description
                                                                                                                                                                    Not reported
                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Source
                                                                                                                                                                    GEO
                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                    sample_accession: GSM5664399
sample_title: HR_29_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-29; response status: Responder; visit: W14; crp: 1.15

                                                                                                                                                                    GSM5664400

                                                                                                                                                                    Excluded

                                                                                                                                                                    HR_30_V1

                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                          • HR_30_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: Baseline; crp: 15.8
                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                            • HR_30_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: Baseline; crp: 15.8
                                                                                                                                                                          Source metadata
                                                                                                                                                                          Source name
                                                                                                                                                                          Whole blood
                                                                                                                                                                          Characteristics
                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: Baseline; crp: 15.8
                                                                                                                                                                          Description
                                                                                                                                                                          Not reported
                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Source
                                                                                                                                                                          GEO
                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                          sample_accession: GSM5664400
sample_title: HR_30_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: Baseline; crp: 15.8

                                                                                                                                                                          GSM5664401

                                                                                                                                                                          Excluded

                                                                                                                                                                          HR_30_V2

                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                • HR_30_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W2; crp: 4.78
                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                  • HR_30_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W2; crp: 4.78
                                                                                                                                                                                Source metadata
                                                                                                                                                                                Source name
                                                                                                                                                                                Whole blood
                                                                                                                                                                                Characteristics
                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W2; crp: 4.78
                                                                                                                                                                                Description
                                                                                                                                                                                Not reported
                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Source
                                                                                                                                                                                GEO
                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                sample_accession: GSM5664401
sample_title: HR_30_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W2; crp: 4.78

                                                                                                                                                                                GSM5664402

                                                                                                                                                                                Excluded

                                                                                                                                                                                HR_30_V3

                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                      • HR_30_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W14; crp: 43.6
                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                        • HR_30_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W14; crp: 43.6
                                                                                                                                                                                      Source metadata
                                                                                                                                                                                      Source name
                                                                                                                                                                                      Whole blood
                                                                                                                                                                                      Characteristics
                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W14; crp: 43.6
                                                                                                                                                                                      Description
                                                                                                                                                                                      Not reported
                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Source
                                                                                                                                                                                      GEO
                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                      sample_accession: GSM5664402
sample_title: HR_30_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-30; response status: Non-responder; visit: W14; crp: 43.6

                                                                                                                                                                                      GSM5664403

                                                                                                                                                                                      Excluded

                                                                                                                                                                                      HR_31_V1

                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                            • HR_31_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: Baseline; crp: 44
                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                              • HR_31_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: Baseline; crp: 44
                                                                                                                                                                                            Source metadata
                                                                                                                                                                                            Source name
                                                                                                                                                                                            Whole blood
                                                                                                                                                                                            Characteristics
                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: Baseline; crp: 44
                                                                                                                                                                                            Description
                                                                                                                                                                                            Not reported
                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Source
                                                                                                                                                                                            GEO
                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                            sample_accession: GSM5664403
sample_title: HR_31_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: Baseline; crp: 44

                                                                                                                                                                                            GSM5664404

                                                                                                                                                                                            Excluded

                                                                                                                                                                                            HR_31_V2

                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                  • HR_31_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W2; crp: 5.43
                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                    • HR_31_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W2; crp: 5.43
                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                  Source name
                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W2; crp: 5.43
                                                                                                                                                                                                  Description
                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Source
                                                                                                                                                                                                  GEO
                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                  sample_accession: GSM5664404
sample_title: HR_31_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W2; crp: 5.43

                                                                                                                                                                                                  GSM5664405

                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                  HR_31_V3

                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                        • HR_31_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W14; crp: 5.9
                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                          • HR_31_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W14; crp: 5.9
                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                        Source name
                                                                                                                                                                                                        Whole blood
                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W14; crp: 5.9
                                                                                                                                                                                                        Description
                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Source
                                                                                                                                                                                                        GEO
                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                        sample_accession: GSM5664405
sample_title: HR_31_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-31; response status: Responder; visit: W14; crp: 5.9

                                                                                                                                                                                                        GSM5664406

                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                        HR_32_V1

                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                              • HR_32_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: Baseline; crp: 16.5
                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                • HR_32_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: Baseline; crp: 16.5
                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                              Source name
                                                                                                                                                                                                              Whole blood
                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: Baseline; crp: 16.5
                                                                                                                                                                                                              Description
                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Source
                                                                                                                                                                                                              GEO
                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                              sample_accession: GSM5664406
sample_title: HR_32_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: Baseline; crp: 16.5

                                                                                                                                                                                                              GSM5664407

                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                              HR_32_V2

                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                    • HR_32_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W2; crp: 3.8
                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                      • HR_32_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W2; crp: 3.8
                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                    Whole blood
                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W2; crp: 3.8
                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                    sample_accession: GSM5664407
sample_title: HR_32_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W2; crp: 3.8

                                                                                                                                                                                                                    GSM5664408

                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                    HR_32_V3

                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                          • HR_32_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W14; crp: 7
                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                            • HR_32_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W14; crp: 7
                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                          Whole blood
                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W14; crp: 7
                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                          sample_accession: GSM5664408
sample_title: HR_32_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-32; response status: Non-responder; visit: W14; crp: 7

                                                                                                                                                                                                                          GSM5664409

                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                          HR_33_V1

                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                • HR_33_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: Baseline; crp: 21.17
                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                  • HR_33_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: Baseline; crp: 21.17
                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                Whole blood
                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: Baseline; crp: 21.17
                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                sample_accession: GSM5664409
sample_title: HR_33_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: Baseline; crp: 21.17

                                                                                                                                                                                                                                GSM5664410

                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                HR_33_V2

                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                      • HR_33_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W2; crp: 1.75
                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                        • HR_33_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W2; crp: 1.75
                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                      Whole blood
                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W2; crp: 1.75
                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                      sample_accession: GSM5664410
sample_title: HR_33_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W2; crp: 1.75

                                                                                                                                                                                                                                      GSM5664411

                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                      HR_33_V3

                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                            • HR_33_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W14; crp: 9.81
                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                              • HR_33_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W14; crp: 9.81
                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                            Whole blood
                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W14; crp: 9.81
                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                            sample_accession: GSM5664411
sample_title: HR_33_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-33; response status: Responder; visit: W14; crp: 9.81

                                                                                                                                                                                                                                            GSM5664412

                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                            HR_35_V1

                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                  • HR_35_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: Baseline; crp: 27.18
                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                    • HR_35_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: Baseline; crp: 27.18
                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: Baseline; crp: 27.18
                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                  sample_accession: GSM5664412
sample_title: HR_35_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: Baseline; crp: 27.18

                                                                                                                                                                                                                                                  GSM5664413

                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                  HR_35_V2

                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                        • HR_35_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W2; crp: 11.22
                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                          • HR_35_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W2; crp: 11.22
                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                        Whole blood
                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W2; crp: 11.22
                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                        sample_accession: GSM5664413
sample_title: HR_35_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W2; crp: 11.22

                                                                                                                                                                                                                                                        GSM5664414

                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                        HR_35_V3

                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                              • HR_35_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W14; crp: 18.3
                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                • HR_35_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W14; crp: 18.3
                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                              Whole blood
                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W14; crp: 18.3
                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                              sample_accession: GSM5664414
sample_title: HR_35_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-35; response status: Responder; visit: W14; crp: 18.3

                                                                                                                                                                                                                                                              GSM5664415

                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                              HR_36_V1

                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                    • HR_36_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: Baseline; crp: 82.7
                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                      • HR_36_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: Baseline; crp: 82.7
                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                    Whole blood
                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: Baseline; crp: 82.7
                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                    sample_accession: GSM5664415
sample_title: HR_36_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: Baseline; crp: 82.7

                                                                                                                                                                                                                                                                    GSM5664416

                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                    HR_36_V2

                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                          • HR_36_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W2; crp: 23.7
                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                            • HR_36_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W2; crp: 23.7
                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                          Whole blood
                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W2; crp: 23.7
                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                          sample_accession: GSM5664416
sample_title: HR_36_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W2; crp: 23.7

                                                                                                                                                                                                                                                                          GSM5664417

                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                          HR_36_V3

                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                • HR_36_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W14; crp: 116
                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                  • HR_36_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W14; crp: 116
                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                Whole blood
                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W14; crp: 116
                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                sample_accession: GSM5664417
sample_title: HR_36_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-36; response status: Non-responder; visit: W14; crp: 116

                                                                                                                                                                                                                                                                                GSM5664418

                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                HR_37_V1

                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                      • HR_37_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: Baseline; crp: 4.26
                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                        • HR_37_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: Baseline; crp: 4.26
                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                      Whole blood
                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: Baseline; crp: 4.26
                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                      sample_accession: GSM5664418
sample_title: HR_37_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: Baseline; crp: 4.26

                                                                                                                                                                                                                                                                                      GSM5664419

                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                      HR_37_V2

                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                            • HR_37_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W2; crp: 2
                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                              • HR_37_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W2; crp: 2
                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                            Whole blood
                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W2; crp: 2
                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                            sample_accession: GSM5664419
sample_title: HR_37_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W2; crp: 2

                                                                                                                                                                                                                                                                                            GSM5664420

                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                            HR_37_V3

                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                  • HR_37_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W14; crp: 7.7
                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                    • HR_37_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W14; crp: 7.7
                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W14; crp: 7.7
                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                  sample_accession: GSM5664420
sample_title: HR_37_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-37; response status: Non-responder; visit: W14; crp: 7.7

                                                                                                                                                                                                                                                                                                  GSM5664421

                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                  HR_20_V1

                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                        • HR_20_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: Baseline; crp: 15.6
                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                          • HR_20_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: Baseline; crp: 15.6
                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                        Whole blood
                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: Baseline; crp: 15.6
                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                        sample_accession: GSM5664421
sample_title: HR_20_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: Baseline; crp: 15.6

                                                                                                                                                                                                                                                                                                        GSM5664422

                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                        HR_20_V2

                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                              • HR_20_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W2; crp: NA
                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                • HR_20_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W2; crp: NA
                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                              Whole blood
                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W2; crp: NA
                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                              sample_accession: GSM5664422
sample_title: HR_20_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W2; crp: NA

                                                                                                                                                                                                                                                                                                              GSM5664423

                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                              HR_20_V3

                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                    • HR_20_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W14; crp: 2.49
                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                      • HR_20_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W14; crp: 2.49
                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                    Whole blood
                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W14; crp: 2.49
                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5664423
sample_title: HR_20_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-20; response status: Responder; visit: W14; crp: 2.49

                                                                                                                                                                                                                                                                                                                    GSM5664424

                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                    HR_21_V1

                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                          • HR_21_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: Baseline; crp: 2.8
                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                            • HR_21_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: Baseline; crp: 2.8
                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                          Whole blood
                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: Baseline; crp: 2.8
                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5664424
sample_title: HR_21_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: Baseline; crp: 2.8

                                                                                                                                                                                                                                                                                                                          GSM5664425

                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                          HR_21_V2

                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                • HR_21_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W2; crp: 0.9
                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                  • HR_21_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W2; crp: 0.9
                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                Whole blood
                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W2; crp: 0.9
                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5664425
sample_title: HR_21_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W2; crp: 0.9

                                                                                                                                                                                                                                                                                                                                GSM5664426

                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                HR_21_V3

                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                      • HR_21_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W14; crp: NA
                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                        • HR_21_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W14; crp: NA
                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                      Whole blood
                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W14; crp: NA
                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5664426
sample_title: HR_21_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-21; response status: Non-responder; visit: W14; crp: NA

                                                                                                                                                                                                                                                                                                                                      GSM5664427

                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                      HR_22_V1

                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                            • HR_22_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: Baseline; crp: 2.16
                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                              • HR_22_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: Baseline; crp: 2.16
                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                            Whole blood
                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: Baseline; crp: 2.16
                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5664427
sample_title: HR_22_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: Baseline; crp: 2.16

                                                                                                                                                                                                                                                                                                                                            GSM5664428

                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                            HR_22_V2

                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                  • HR_22_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W2; crp: 1.8
                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                    • HR_22_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W2; crp: 1.8
                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W2; crp: 1.8
                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5664428
sample_title: HR_22_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W2; crp: 1.8

                                                                                                                                                                                                                                                                                                                                                  GSM5664429

                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                  HR_22_V3

                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                        • HR_22_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W14; crp: 1.2
                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                          • HR_22_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W14; crp: 1.2
                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                        Whole blood
                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W14; crp: 1.2
                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5664429
sample_title: HR_22_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-22; response status: Responder; visit: W14; crp: 1.2

                                                                                                                                                                                                                                                                                                                                                        GSM5664430

                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                        HR_23_V1

                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                              • HR_23_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: Baseline; crp: 5.7
                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                • HR_23_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: Baseline; crp: 5.7
                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                              Whole blood
                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: Baseline; crp: 5.7
                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5664430
sample_title: HR_23_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: Baseline; crp: 5.7

                                                                                                                                                                                                                                                                                                                                                              GSM5664431

                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                              HR_23_V2

                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                    • HR_23_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W2; crp: 13
                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                      • HR_23_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W2; crp: 13
                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                    Whole blood
                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W2; crp: 13
                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5664431
sample_title: HR_23_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W2; crp: 13

                                                                                                                                                                                                                                                                                                                                                                    GSM5664432

                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                    HR_23_V3

                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                          • HR_23_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W14; crp: 28.6
                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                            • HR_23_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W14; crp: 28.6
                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                          Whole blood
                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W14; crp: 28.6
                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5664432
sample_title: HR_23_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-23; response status: Non-responder; visit: W14; crp: 28.6

                                                                                                                                                                                                                                                                                                                                                                          GSM5664433

                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                          HR_24_V1

                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                • HR_24_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: Baseline; crp: 2.44
                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                  • HR_24_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: Baseline; crp: 2.44
                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                Whole blood
                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: Baseline; crp: 2.44
                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5664433
sample_title: HR_24_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: Baseline; crp: 2.44

                                                                                                                                                                                                                                                                                                                                                                                GSM5664434

                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                HR_24_V2

                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                      • HR_24_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                        • HR_24_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                      Whole blood
                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W2; crp: 2.5
                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5664434
sample_title: HR_24_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W2; crp: 2.5

                                                                                                                                                                                                                                                                                                                                                                                      GSM5664435

                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                      HR_24_V3

                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                            • HR_24_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W14; crp: 3.5
                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                              • HR_24_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W14; crp: 3.5
                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                            Whole blood
                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W14; crp: 3.5
                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5664435
sample_title: HR_24_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-24; response status: Responder; visit: W14; crp: 3.5

                                                                                                                                                                                                                                                                                                                                                                                            GSM5664436

                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                            HR_26_V1

                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                  • HR_26_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: Baseline; crp: 3.1
                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                    • HR_26_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: Baseline; crp: 3.1
                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: Baseline; crp: 3.1
                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5664436
sample_title: HR_26_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: Baseline; crp: 3.1

                                                                                                                                                                                                                                                                                                                                                                                                  GSM5664437

                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                  HR_26_V2

                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                        • HR_26_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W2; crp: 2.3
                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                          • HR_26_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W2; crp: 2.3
                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                        Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                        disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W2; crp: 2.3
                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5664437
sample_title: HR_26_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W2; crp: 2.3

                                                                                                                                                                                                                                                                                                                                                                                                        GSM5664438

                                                                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                                                                        HR_26_V3

                                                                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                              • HR_26_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W14; crp: 16
                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                • HR_26_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W14; crp: 16
                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                              Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                              disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W14; crp: 16
                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5664438
sample_title: HR_26_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-26; response status: Non-responder; visit: W14; crp: 16

                                                                                                                                                                                                                                                                                                                                                                                                              GSM5664439

                                                                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                                                                              HR_27_V1

                                                                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                    • HR_27_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: Baseline; crp: 19.2
                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                      • HR_27_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: Baseline; crp: 19.2
                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                    Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                    disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: Baseline; crp: 19.2
                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5664439
sample_title: HR_27_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: Baseline; crp: 19.2

                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5664440

                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                    HR_27_V2

                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                          • HR_27_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W2; crp: 20.2
                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                            • HR_27_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W2; crp: 20.2
                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                          Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                          disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W2; crp: 20.2
                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5664440
sample_title: HR_27_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W2; crp: 20.2

                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5664441

                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                          HR_27_V3

                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                • HR_27_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W14; crp: 2.9
                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • HR_27_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W14; crp: 2.9
                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W14; crp: 2.9
                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5664441
sample_title: HR_27_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-27; response status: Non-responder; visit: W14; crp: 2.9

                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5664442

                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                HR_28_V1

                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • HR_28_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: Baseline; crp: 1.6
                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • HR_28_V1 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: Baseline; crp: 1.6
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                      Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                      disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: Baseline; crp: 1.6
                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5664442
sample_title: HR_28_V1
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: Baseline; crp: 1.6

                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5664443

                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                      HR_28_V2

                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • HR_28_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W2; crp: 1.5
                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • HR_28_V2 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W2; crp: 1.5
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                            Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                            disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W2; crp: 1.5
                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5664443
sample_title: HR_28_V2
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W2; crp: 1.5

                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5664444

                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                            HR_28_V3

                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HR_28_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W14; crp: 0.5
                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HR_28_V3 Whole blood disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W14; crp: 0.5
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Whole blood
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                  disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W14; crp: 0.5
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5664444
sample_title: HR_28_V3
source_name: Whole blood
characteristics: disease: Crohn's disease; treatment: Infliximab; patient: HR-28; response status: Responder; visit: W14; crp: 0.5