Matching samples

GSE193066 · Transcriptome profile of liver biopsy tissues from patients with non-alcoholic fatty liver disease (tissue validation set 1).

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

164 case / 0 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (164)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

GSM5772501

Uncertain

HUnafld001

Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Insufficient evidence
        • The required value is not reported.
        • HUnafld001 HUnafld001 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
        • HUnafld001 HUnafld001 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
        • Supported by the indexed evidence.
        • specimen category excludes: Biofluid — Insufficient evidence
          • The required value is not reported.
          • HUnafld001 HUnafld001 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
          • HUnafld001 HUnafld001 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
        Source metadata
        Source name
        HUnafld001
        Characteristics
        tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
        Description
        Not reported
        Indexed organism evidence
        INFERRED · PARENT_INHERITED: Not reported
        Indexed assay evidence
        INFERRED · PARENT_INHERITED: Not reported
        Source
        GEO
        Original indexed metadata
        sample_accession: GSM5772501
sample_title: HUnafld001
source_name: HUnafld001
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: female; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

        GSM5772502

        Uncertain

        HUnafld002

        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

        Requirements and decision evidence
        • organism: Homo sapiens — Insufficient evidence
          • The required value is not reported.
          • assay type: bulk RNA-seq — Insufficient evidence
            • The required value is not reported.
            • specimen category: Tissue or biopsy — Insufficient evidence
              • The required value is not reported.
              • HUnafld002 HUnafld002 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
              • HUnafld002 HUnafld002 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
              • Supported by the indexed evidence.
              • specimen category excludes: Biofluid — Insufficient evidence
                • The required value is not reported.
                • HUnafld002 HUnafld002 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
                • HUnafld002 HUnafld002 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
              Source metadata
              Source name
              HUnafld002
              Characteristics
              tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
              Description
              Not reported
              Indexed organism evidence
              INFERRED · PARENT_INHERITED: Not reported
              Indexed assay evidence
              INFERRED · PARENT_INHERITED: Not reported
              Source
              GEO
              Original indexed metadata
              sample_accession: GSM5772502
sample_title: HUnafld002
source_name: HUnafld002
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk

              GSM5772503

              Uncertain

              HUnafld003

              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

              Requirements and decision evidence
              • organism: Homo sapiens — Insufficient evidence
                • The required value is not reported.
                • assay type: bulk RNA-seq — Insufficient evidence
                  • The required value is not reported.
                  • specimen category: Tissue or biopsy — Insufficient evidence
                    • The required value is not reported.
                    • HUnafld003 HUnafld003 tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                    • HUnafld003 HUnafld003 tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Insufficient evidence
                      • The required value is not reported.
                      • HUnafld003 HUnafld003 tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                      • HUnafld003 HUnafld003 tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                    Source metadata
                    Source name
                    HUnafld003
                    Characteristics
                    tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                    Description
                    Not reported
                    Indexed organism evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Indexed assay evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Source
                    GEO
                    Original indexed metadata
                    sample_accession: GSM5772503
sample_title: HUnafld003
source_name: HUnafld003
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 65; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                    GSM5772504

                    Uncertain

                    HUnafld004

                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                    Requirements and decision evidence
                    • organism: Homo sapiens — Insufficient evidence
                      • The required value is not reported.
                      • assay type: bulk RNA-seq — Insufficient evidence
                        • The required value is not reported.
                        • specimen category: Tissue or biopsy — Insufficient evidence
                          • The required value is not reported.
                          • HUnafld004 HUnafld004 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                          • HUnafld004 HUnafld004 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                          • Supported by the indexed evidence.
                          • specimen category excludes: Biofluid — Insufficient evidence
                            • The required value is not reported.
                            • HUnafld004 HUnafld004 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                            • HUnafld004 HUnafld004 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                          Source metadata
                          Source name
                          HUnafld004
                          Characteristics
                          tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                          Description
                          Not reported
                          Indexed organism evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Indexed assay evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Source
                          GEO
                          Original indexed metadata
                          sample_accession: GSM5772504
sample_title: HUnafld004
source_name: HUnafld004
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                          GSM5772505

                          Uncertain

                          HUnafld005

                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                          Requirements and decision evidence
                          • organism: Homo sapiens — Insufficient evidence
                            • The required value is not reported.
                            • assay type: bulk RNA-seq — Insufficient evidence
                              • The required value is not reported.
                              • specimen category: Tissue or biopsy — Insufficient evidence
                                • The required value is not reported.
                                • HUnafld005 HUnafld005 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                • HUnafld005 HUnafld005 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                • Supported by the indexed evidence.
                                • specimen category excludes: Biofluid — Insufficient evidence
                                  • The required value is not reported.
                                  • HUnafld005 HUnafld005 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                  • HUnafld005 HUnafld005 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                Source metadata
                                Source name
                                HUnafld005
                                Characteristics
                                tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                Description
                                Not reported
                                Indexed organism evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Indexed assay evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Source
                                GEO
                                Original indexed metadata
                                sample_accession: GSM5772505
sample_title: HUnafld005
source_name: HUnafld005
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                GSM5772506

                                Uncertain

                                HUnafld006

                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                Requirements and decision evidence
                                • organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                      • The required value is not reported.
                                      • HUnafld006 HUnafld006 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                      • HUnafld006 HUnafld006 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                      • Supported by the indexed evidence.
                                      • specimen category excludes: Biofluid — Insufficient evidence
                                        • The required value is not reported.
                                        • HUnafld006 HUnafld006 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                        • HUnafld006 HUnafld006 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                      Source metadata
                                      Source name
                                      HUnafld006
                                      Characteristics
                                      tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                      Description
                                      Not reported
                                      Indexed organism evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Indexed assay evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Source
                                      GEO
                                      Original indexed metadata
                                      sample_accession: GSM5772506
sample_title: HUnafld006
source_name: HUnafld006
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                      GSM5772507

                                      Uncertain

                                      HUnafld007

                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                      Requirements and decision evidence
                                      • organism: Homo sapiens — Insufficient evidence
                                        • The required value is not reported.
                                        • assay type: bulk RNA-seq — Insufficient evidence
                                          • The required value is not reported.
                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                            • The required value is not reported.
                                            • HUnafld007 HUnafld007 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                            • HUnafld007 HUnafld007 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                            • Supported by the indexed evidence.
                                            • specimen category excludes: Biofluid — Insufficient evidence
                                              • The required value is not reported.
                                              • HUnafld007 HUnafld007 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                              • HUnafld007 HUnafld007 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                            Source metadata
                                            Source name
                                            HUnafld007
                                            Characteristics
                                            tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                            Description
                                            Not reported
                                            Indexed organism evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Indexed assay evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Source
                                            GEO
                                            Original indexed metadata
                                            sample_accession: GSM5772507
sample_title: HUnafld007
source_name: HUnafld007
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                            GSM5772508

                                            Uncertain

                                            HUnafld008

                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                            Requirements and decision evidence
                                            • organism: Homo sapiens — Insufficient evidence
                                              • The required value is not reported.
                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                • The required value is not reported.
                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                  • The required value is not reported.
                                                  • HUnafld008 HUnafld008 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                  • HUnafld008 HUnafld008 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                    • The required value is not reported.
                                                    • HUnafld008 HUnafld008 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                    • HUnafld008 HUnafld008 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                  Source metadata
                                                  Source name
                                                  HUnafld008
                                                  Characteristics
                                                  tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                  Description
                                                  Not reported
                                                  Indexed organism evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Indexed assay evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Source
                                                  GEO
                                                  Original indexed metadata
                                                  sample_accession: GSM5772508
sample_title: HUnafld008
source_name: HUnafld008
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 0; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                  GSM5772509

                                                  Uncertain

                                                  HUnafld009

                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                  Requirements and decision evidence
                                                  • organism: Homo sapiens — Insufficient evidence
                                                    • The required value is not reported.
                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                      • The required value is not reported.
                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                        • The required value is not reported.
                                                        • HUnafld009 HUnafld009 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                        • HUnafld009 HUnafld009 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                        • Supported by the indexed evidence.
                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                          • The required value is not reported.
                                                          • HUnafld009 HUnafld009 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                          • HUnafld009 HUnafld009 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                        Source metadata
                                                        Source name
                                                        HUnafld009
                                                        Characteristics
                                                        tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                        Description
                                                        Not reported
                                                        Indexed organism evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Indexed assay evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Source
                                                        GEO
                                                        Original indexed metadata
                                                        sample_accession: GSM5772509
sample_title: HUnafld009
source_name: HUnafld009
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                        GSM5772510

                                                        Uncertain

                                                        HUnafld010

                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                        Requirements and decision evidence
                                                        • organism: Homo sapiens — Insufficient evidence
                                                          • The required value is not reported.
                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                            • The required value is not reported.
                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                              • The required value is not reported.
                                                              • HUnafld010 HUnafld010 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                              • HUnafld010 HUnafld010 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                • The required value is not reported.
                                                                • HUnafld010 HUnafld010 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                • HUnafld010 HUnafld010 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                              Source metadata
                                                              Source name
                                                              HUnafld010
                                                              Characteristics
                                                              tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM5772510
sample_title: HUnafld010
source_name: HUnafld010
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                              GSM5772511

                                                              Uncertain

                                                              HUnafld011

                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                              Requirements and decision evidence
                                                              • organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                    • The required value is not reported.
                                                                    • HUnafld011 HUnafld011 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                    • HUnafld011 HUnafld011 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                    • Supported by the indexed evidence.
                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                      • The required value is not reported.
                                                                      • HUnafld011 HUnafld011 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                      • HUnafld011 HUnafld011 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                    Source metadata
                                                                    Source name
                                                                    HUnafld011
                                                                    Characteristics
                                                                    tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                    Description
                                                                    Not reported
                                                                    Indexed organism evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Indexed assay evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Source
                                                                    GEO
                                                                    Original indexed metadata
                                                                    sample_accession: GSM5772511
sample_title: HUnafld011
source_name: HUnafld011
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: male; fibrosis stage: 0; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                    GSM5772512

                                                                    Uncertain

                                                                    HUnafld012

                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                    Requirements and decision evidence
                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                      • The required value is not reported.
                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                        • The required value is not reported.
                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                          • The required value is not reported.
                                                                          • HUnafld012 HUnafld012 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                          • HUnafld012 HUnafld012 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                          • Supported by the indexed evidence.
                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • HUnafld012 HUnafld012 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                            • HUnafld012 HUnafld012 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                          Source metadata
                                                                          Source name
                                                                          HUnafld012
                                                                          Characteristics
                                                                          tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                          Description
                                                                          Not reported
                                                                          Indexed organism evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Indexed assay evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Source
                                                                          GEO
                                                                          Original indexed metadata
                                                                          sample_accession: GSM5772512
sample_title: HUnafld012
source_name: HUnafld012
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 0; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                          GSM5772513

                                                                          Uncertain

                                                                          HUnafld013

                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                          Requirements and decision evidence
                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                • The required value is not reported.
                                                                                • HUnafld013 HUnafld013 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                • HUnafld013 HUnafld013 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                  • The required value is not reported.
                                                                                  • HUnafld013 HUnafld013 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                  • HUnafld013 HUnafld013 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                Source metadata
                                                                                Source name
                                                                                HUnafld013
                                                                                Characteristics
                                                                                tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                Description
                                                                                Not reported
                                                                                Indexed organism evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Indexed assay evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Source
                                                                                GEO
                                                                                Original indexed metadata
                                                                                sample_accession: GSM5772513
sample_title: HUnafld013
source_name: HUnafld013
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 0; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                GSM5772514

                                                                                Uncertain

                                                                                HUnafld015

                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                Requirements and decision evidence
                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                  • The required value is not reported.
                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                      • The required value is not reported.
                                                                                      • HUnafld015 HUnafld015 tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                      • HUnafld015 HUnafld015 tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                      • Supported by the indexed evidence.
                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • HUnafld015 HUnafld015 tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                        • HUnafld015 HUnafld015 tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                      Source metadata
                                                                                      Source name
                                                                                      HUnafld015
                                                                                      Characteristics
                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                      Description
                                                                                      Not reported
                                                                                      Indexed organism evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Indexed assay evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Source
                                                                                      GEO
                                                                                      Original indexed metadata
                                                                                      sample_accession: GSM5772514
sample_title: HUnafld015
source_name: HUnafld015
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 40; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                      GSM5772515

                                                                                      Uncertain

                                                                                      HUnafld016

                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                      Requirements and decision evidence
                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                          • The required value is not reported.
                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                            • The required value is not reported.
                                                                                            • HUnafld016 HUnafld016 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                            • HUnafld016 HUnafld016 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • HUnafld016 HUnafld016 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                              • HUnafld016 HUnafld016 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                            Source metadata
                                                                                            Source name
                                                                                            HUnafld016
                                                                                            Characteristics
                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                            Description
                                                                                            Not reported
                                                                                            Indexed organism evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Indexed assay evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Source
                                                                                            GEO
                                                                                            Original indexed metadata
                                                                                            sample_accession: GSM5772515
sample_title: HUnafld016
source_name: HUnafld016
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                            GSM5772516

                                                                                            Uncertain

                                                                                            HUnafld017

                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                            Requirements and decision evidence
                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                  • The required value is not reported.
                                                                                                  • HUnafld017 HUnafld017 tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                  • HUnafld017 HUnafld017 tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                  • Supported by the indexed evidence.
                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                    • The required value is not reported.
                                                                                                    • HUnafld017 HUnafld017 tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                    • HUnafld017 HUnafld017 tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                  Source metadata
                                                                                                  Source name
                                                                                                  HUnafld017
                                                                                                  Characteristics
                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                  Description
                                                                                                  Not reported
                                                                                                  Indexed organism evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Indexed assay evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Source
                                                                                                  GEO
                                                                                                  Original indexed metadata
                                                                                                  sample_accession: GSM5772516
sample_title: HUnafld017
source_name: HUnafld017
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 66; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                  GSM5772517

                                                                                                  Uncertain

                                                                                                  HUnafld018

                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                  Requirements and decision evidence
                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                    • The required value is not reported.
                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                      • The required value is not reported.
                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                        • The required value is not reported.
                                                                                                        • HUnafld018 HUnafld018 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                        • HUnafld018 HUnafld018 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                        • Supported by the indexed evidence.
                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • HUnafld018 HUnafld018 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                          • HUnafld018 HUnafld018 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                        Source metadata
                                                                                                        Source name
                                                                                                        HUnafld018
                                                                                                        Characteristics
                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                        Description
                                                                                                        Not reported
                                                                                                        Indexed organism evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Indexed assay evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Source
                                                                                                        GEO
                                                                                                        Original indexed metadata
                                                                                                        sample_accession: GSM5772517
sample_title: HUnafld018
source_name: HUnafld018
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                        GSM5772518

                                                                                                        Uncertain

                                                                                                        HUnafld019

                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                        Requirements and decision evidence
                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                              • The required value is not reported.
                                                                                                              • HUnafld019 HUnafld019 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                              • HUnafld019 HUnafld019 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                • The required value is not reported.
                                                                                                                • HUnafld019 HUnafld019 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                • HUnafld019 HUnafld019 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                              Source metadata
                                                                                                              Source name
                                                                                                              HUnafld019
                                                                                                              Characteristics
                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                              Description
                                                                                                              Not reported
                                                                                                              Indexed organism evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Indexed assay evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Source
                                                                                                              GEO
                                                                                                              Original indexed metadata
                                                                                                              sample_accession: GSM5772518
sample_title: HUnafld019
source_name: HUnafld019
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                              GSM5772519

                                                                                                              Uncertain

                                                                                                              HUnafld020

                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                              Requirements and decision evidence
                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                • The required value is not reported.
                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                    • The required value is not reported.
                                                                                                                    • HUnafld020 HUnafld020 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                    • HUnafld020 HUnafld020 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                    • Supported by the indexed evidence.
                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • HUnafld020 HUnafld020 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                      • HUnafld020 HUnafld020 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                    Source metadata
                                                                                                                    Source name
                                                                                                                    HUnafld020
                                                                                                                    Characteristics
                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                    Description
                                                                                                                    Not reported
                                                                                                                    Indexed organism evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Indexed assay evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Source
                                                                                                                    GEO
                                                                                                                    Original indexed metadata
                                                                                                                    sample_accession: GSM5772519
sample_title: HUnafld020
source_name: HUnafld020
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                    GSM5772520

                                                                                                                    Uncertain

                                                                                                                    HUnafld021

                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                    Requirements and decision evidence
                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                        • The required value is not reported.
                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                          • The required value is not reported.
                                                                                                                          • HUnafld021 HUnafld021 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                          • HUnafld021 HUnafld021 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • HUnafld021 HUnafld021 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                            • HUnafld021 HUnafld021 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                          Source metadata
                                                                                                                          Source name
                                                                                                                          HUnafld021
                                                                                                                          Characteristics
                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                          Description
                                                                                                                          Not reported
                                                                                                                          Indexed organism evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Indexed assay evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Source
                                                                                                                          GEO
                                                                                                                          Original indexed metadata
                                                                                                                          sample_accession: GSM5772520
sample_title: HUnafld021
source_name: HUnafld021
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                          GSM5772521

                                                                                                                          Uncertain

                                                                                                                          HUnafld023

                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                          Requirements and decision evidence
                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                • The required value is not reported.
                                                                                                                                • HUnafld023 HUnafld023 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                • HUnafld023 HUnafld023 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                  • The required value is not reported.
                                                                                                                                  • HUnafld023 HUnafld023 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                  • HUnafld023 HUnafld023 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                Source metadata
                                                                                                                                Source name
                                                                                                                                HUnafld023
                                                                                                                                Characteristics
                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                Description
                                                                                                                                Not reported
                                                                                                                                Indexed organism evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Indexed assay evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Source
                                                                                                                                GEO
                                                                                                                                Original indexed metadata
                                                                                                                                sample_accession: GSM5772521
sample_title: HUnafld023
source_name: HUnafld023
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                GSM5772522

                                                                                                                                Uncertain

                                                                                                                                HUnafld024

                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                Requirements and decision evidence
                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                  • The required value is not reported.
                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                    • The required value is not reported.
                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                      • The required value is not reported.
                                                                                                                                      • HUnafld024 HUnafld024 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                      • HUnafld024 HUnafld024 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • HUnafld024 HUnafld024 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                        • HUnafld024 HUnafld024 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                      Source metadata
                                                                                                                                      Source name
                                                                                                                                      HUnafld024
                                                                                                                                      Characteristics
                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                      Description
                                                                                                                                      Not reported
                                                                                                                                      Indexed organism evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Indexed assay evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Source
                                                                                                                                      GEO
                                                                                                                                      Original indexed metadata
                                                                                                                                      sample_accession: GSM5772522
sample_title: HUnafld024
source_name: HUnafld024
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                      GSM5772523

                                                                                                                                      Uncertain

                                                                                                                                      HUnafld025

                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                      Requirements and decision evidence
                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                            • The required value is not reported.
                                                                                                                                            • HUnafld025 HUnafld025 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                            • HUnafld025 HUnafld025 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                              • The required value is not reported.
                                                                                                                                              • HUnafld025 HUnafld025 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                              • HUnafld025 HUnafld025 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                            Source metadata
                                                                                                                                            Source name
                                                                                                                                            HUnafld025
                                                                                                                                            Characteristics
                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                            Description
                                                                                                                                            Not reported
                                                                                                                                            Indexed organism evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Indexed assay evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Source
                                                                                                                                            GEO
                                                                                                                                            Original indexed metadata
                                                                                                                                            sample_accession: GSM5772523
sample_title: HUnafld025
source_name: HUnafld025
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                            GSM5772524

                                                                                                                                            Uncertain

                                                                                                                                            HUnafld026

                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                            Requirements and decision evidence
                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                              • The required value is not reported.
                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                  • The required value is not reported.
                                                                                                                                                  • HUnafld026 HUnafld026 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                  • HUnafld026 HUnafld026 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • HUnafld026 HUnafld026 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                    • HUnafld026 HUnafld026 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                  Source metadata
                                                                                                                                                  Source name
                                                                                                                                                  HUnafld026
                                                                                                                                                  Characteristics
                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                  Description
                                                                                                                                                  Not reported
                                                                                                                                                  Indexed organism evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Indexed assay evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Source
                                                                                                                                                  GEO
                                                                                                                                                  Original indexed metadata
                                                                                                                                                  sample_accession: GSM5772524
sample_title: HUnafld026
source_name: HUnafld026
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                  GSM5772525

                                                                                                                                                  Uncertain

                                                                                                                                                  HUnafld027

                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                      • The required value is not reported.
                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                        • The required value is not reported.
                                                                                                                                                        • HUnafld027 HUnafld027 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                        • HUnafld027 HUnafld027 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • HUnafld027 HUnafld027 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                          • HUnafld027 HUnafld027 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                        Source metadata
                                                                                                                                                        Source name
                                                                                                                                                        HUnafld027
                                                                                                                                                        Characteristics
                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                        Description
                                                                                                                                                        Not reported
                                                                                                                                                        Indexed organism evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Indexed assay evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Source
                                                                                                                                                        GEO
                                                                                                                                                        Original indexed metadata
                                                                                                                                                        sample_accession: GSM5772525
sample_title: HUnafld027
source_name: HUnafld027
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                        GSM5772526

                                                                                                                                                        Uncertain

                                                                                                                                                        HUnafld029

                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                              • The required value is not reported.
                                                                                                                                                              • HUnafld029 HUnafld029 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                              • HUnafld029 HUnafld029 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                • HUnafld029 HUnafld029 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                • HUnafld029 HUnafld029 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                              Source metadata
                                                                                                                                                              Source name
                                                                                                                                                              HUnafld029
                                                                                                                                                              Characteristics
                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                              Description
                                                                                                                                                              Not reported
                                                                                                                                                              Indexed organism evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Indexed assay evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Source
                                                                                                                                                              GEO
                                                                                                                                                              Original indexed metadata
                                                                                                                                                              sample_accession: GSM5772526
sample_title: HUnafld029
source_name: HUnafld029
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                              GSM5772527

                                                                                                                                                              Uncertain

                                                                                                                                                              HUnafld034

                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                    • HUnafld034 HUnafld034 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                    • HUnafld034 HUnafld034 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • HUnafld034 HUnafld034 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                      • HUnafld034 HUnafld034 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                    Source metadata
                                                                                                                                                                    Source name
                                                                                                                                                                    HUnafld034
                                                                                                                                                                    Characteristics
                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                    Description
                                                                                                                                                                    Not reported
                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Source
                                                                                                                                                                    GEO
                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                    sample_accession: GSM5772527
sample_title: HUnafld034
source_name: HUnafld034
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                    GSM5772528

                                                                                                                                                                    Uncertain

                                                                                                                                                                    HUnafld035_1

                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                          • HUnafld035_1 HUnafld035_1 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                          • HUnafld035_1 HUnafld035_1 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                            • HUnafld035_1 HUnafld035_1 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                            • HUnafld035_1 HUnafld035_1 tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                          Source metadata
                                                                                                                                                                          Source name
                                                                                                                                                                          HUnafld035_1
                                                                                                                                                                          Characteristics
                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                          Description
                                                                                                                                                                          Not reported
                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Source
                                                                                                                                                                          GEO
                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                          sample_accession: GSM5772528
sample_title: HUnafld035_1
source_name: HUnafld035_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 20; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                          GSM5772529

                                                                                                                                                                          Uncertain

                                                                                                                                                                          HUnafld036

                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                • HUnafld036 HUnafld036 tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                • HUnafld036 HUnafld036 tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • HUnafld036 HUnafld036 tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                  • HUnafld036 HUnafld036 tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                Source metadata
                                                                                                                                                                                Source name
                                                                                                                                                                                HUnafld036
                                                                                                                                                                                Characteristics
                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                Description
                                                                                                                                                                                Not reported
                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Source
                                                                                                                                                                                GEO
                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                sample_accession: GSM5772529
sample_title: HUnafld036
source_name: HUnafld036
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 39; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                GSM5772530

                                                                                                                                                                                Uncertain

                                                                                                                                                                                HUnafld037

                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                      • HUnafld037 HUnafld037 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                      • HUnafld037 HUnafld037 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • HUnafld037 HUnafld037 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                        • HUnafld037 HUnafld037 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                      Source metadata
                                                                                                                                                                                      Source name
                                                                                                                                                                                      HUnafld037
                                                                                                                                                                                      Characteristics
                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                      Description
                                                                                                                                                                                      Not reported
                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Source
                                                                                                                                                                                      GEO
                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                      sample_accession: GSM5772530
sample_title: HUnafld037
source_name: HUnafld037
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                      GSM5772531

                                                                                                                                                                                      Uncertain

                                                                                                                                                                                      HUnafld038_1

                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                            • HUnafld038_1 HUnafld038_1 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                            • HUnafld038_1 HUnafld038_1 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                              • HUnafld038_1 HUnafld038_1 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                              • HUnafld038_1 HUnafld038_1 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                            Source metadata
                                                                                                                                                                                            Source name
                                                                                                                                                                                            HUnafld038_1
                                                                                                                                                                                            Characteristics
                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                            Description
                                                                                                                                                                                            Not reported
                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Source
                                                                                                                                                                                            GEO
                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                            sample_accession: GSM5772531
sample_title: HUnafld038_1
source_name: HUnafld038_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                            GSM5772532

                                                                                                                                                                                            Uncertain

                                                                                                                                                                                            HUnafld039_1

                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                  • HUnafld039_1 HUnafld039_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                  • HUnafld039_1 HUnafld039_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • HUnafld039_1 HUnafld039_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                    • HUnafld039_1 HUnafld039_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                  Source name
                                                                                                                                                                                                  HUnafld039_1
                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                  Description
                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Source
                                                                                                                                                                                                  GEO
                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                  sample_accession: GSM5772532
sample_title: HUnafld039_1
source_name: HUnafld039_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                  GSM5772533

                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                  HUnafld040

                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                        • HUnafld040 HUnafld040 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                        • HUnafld040 HUnafld040 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                          • HUnafld040 HUnafld040 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                          • HUnafld040 HUnafld040 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                        Source name
                                                                                                                                                                                                        HUnafld040
                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                        Description
                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Source
                                                                                                                                                                                                        GEO
                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                        sample_accession: GSM5772533
sample_title: HUnafld040
source_name: HUnafld040
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                        GSM5772534

                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                        HUnafld041

                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                              • HUnafld041 HUnafld041 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                              • HUnafld041 HUnafld041 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • HUnafld041 HUnafld041 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                • HUnafld041 HUnafld041 tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                              Source name
                                                                                                                                                                                                              HUnafld041
                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                              Description
                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Source
                                                                                                                                                                                                              GEO
                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                              sample_accession: GSM5772534
sample_title: HUnafld041
source_name: HUnafld041
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 41; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                              GSM5772535

                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                              HUnafld042

                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                    • HUnafld042 HUnafld042 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                    • HUnafld042 HUnafld042 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • HUnafld042 HUnafld042 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                      • HUnafld042 HUnafld042 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                    HUnafld042
                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                    sample_accession: GSM5772535
sample_title: HUnafld042
source_name: HUnafld042
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                    GSM5772536

                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                    HUnafld043

                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                          • HUnafld043 HUnafld043 tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                          • HUnafld043 HUnafld043 tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                            • HUnafld043 HUnafld043 tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                            • HUnafld043 HUnafld043 tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                          HUnafld043
                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                          sample_accession: GSM5772536
sample_title: HUnafld043
source_name: HUnafld043
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                          GSM5772537

                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                          HUnafld044

                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                • HUnafld044 HUnafld044 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                • HUnafld044 HUnafld044 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • HUnafld044 HUnafld044 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                  • HUnafld044 HUnafld044 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                HUnafld044
                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                sample_accession: GSM5772537
sample_title: HUnafld044
source_name: HUnafld044
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                GSM5772538

                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                HUnafld045

                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                      • HUnafld045 HUnafld045 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                      • HUnafld045 HUnafld045 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                        • HUnafld045 HUnafld045 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                        • HUnafld045 HUnafld045 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                      HUnafld045
                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                      sample_accession: GSM5772538
sample_title: HUnafld045
source_name: HUnafld045
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                      GSM5772539

                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                      HUnafld046_1

                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                            • HUnafld046_1 HUnafld046_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                            • HUnafld046_1 HUnafld046_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • HUnafld046_1 HUnafld046_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                              • HUnafld046_1 HUnafld046_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                            HUnafld046_1
                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                            sample_accession: GSM5772539
sample_title: HUnafld046_1
source_name: HUnafld046_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                            GSM5772540

                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                            HUnafld047_1

                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                  • HUnafld047_1 HUnafld047_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                  • HUnafld047_1 HUnafld047_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • HUnafld047_1 HUnafld047_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                    • HUnafld047_1 HUnafld047_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                  HUnafld047_1
                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                  sample_accession: GSM5772540
sample_title: HUnafld047_1
source_name: HUnafld047_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                  GSM5772541

                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                  HUnafld048_1

                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                        • HUnafld048_1 HUnafld048_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                        • HUnafld048_1 HUnafld048_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                          • HUnafld048_1 HUnafld048_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                          • HUnafld048_1 HUnafld048_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                        HUnafld048_1
                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                        sample_accession: GSM5772541
sample_title: HUnafld048_1
source_name: HUnafld048_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                        GSM5772542

                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                        HUnafld049_1

                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                              • HUnafld049_1 HUnafld049_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                              • HUnafld049_1 HUnafld049_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • HUnafld049_1 HUnafld049_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                • HUnafld049_1 HUnafld049_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                              HUnafld049_1
                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                              sample_accession: GSM5772542
sample_title: HUnafld049_1
source_name: HUnafld049_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                              GSM5772543

                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                              HUnafld050_1

                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                    • HUnafld050_1 HUnafld050_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                    • HUnafld050_1 HUnafld050_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                      • HUnafld050_1 HUnafld050_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                      • HUnafld050_1 HUnafld050_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                    HUnafld050_1
                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                    sample_accession: GSM5772543
sample_title: HUnafld050_1
source_name: HUnafld050_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                    GSM5772544

                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                    HUnafld051

                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                          • HUnafld051 HUnafld051 tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                          • HUnafld051 HUnafld051 tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • HUnafld051 HUnafld051 tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                            • HUnafld051 HUnafld051 tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                          HUnafld051
                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                          sample_accession: GSM5772544
sample_title: HUnafld051
source_name: HUnafld051
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 52; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                          GSM5772545

                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                          HUnafld052_1

                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                • HUnafld052_1 HUnafld052_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                • HUnafld052_1 HUnafld052_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • HUnafld052_1 HUnafld052_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                  • HUnafld052_1 HUnafld052_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                HUnafld052_1
                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                sample_accession: GSM5772545
sample_title: HUnafld052_1
source_name: HUnafld052_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: male; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                GSM5772546

                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                HUnafld053_1

                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                      • HUnafld053_1 HUnafld053_1 tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                      • HUnafld053_1 HUnafld053_1 tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                        • HUnafld053_1 HUnafld053_1 tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                        • HUnafld053_1 HUnafld053_1 tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                      HUnafld053_1
                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                      sample_accession: GSM5772546
sample_title: HUnafld053_1
source_name: HUnafld053_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 49; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                      GSM5772547

                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                      HUnafld054_1

                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                            • HUnafld054_1 HUnafld054_1 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                            • HUnafld054_1 HUnafld054_1 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                              • HUnafld054_1 HUnafld054_1 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                              • HUnafld054_1 HUnafld054_1 tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                            HUnafld054_1
                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                            sample_accession: GSM5772547
sample_title: HUnafld054_1
source_name: HUnafld054_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 45; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                            GSM5772548

                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                            HUnafld055

                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                  • HUnafld055 HUnafld055 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                  • HUnafld055 HUnafld055 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                    • HUnafld055 HUnafld055 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                    • HUnafld055 HUnafld055 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                  HUnafld055
                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772548
sample_title: HUnafld055
source_name: HUnafld055
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                  GSM5772549

                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                  HUnafld056_1

                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                        • HUnafld056_1 HUnafld056_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                        • HUnafld056_1 HUnafld056_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                          • HUnafld056_1 HUnafld056_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                          • HUnafld056_1 HUnafld056_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                        HUnafld056_1
                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772549
sample_title: HUnafld056_1
source_name: HUnafld056_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                        GSM5772550

                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                        HUnafld057_1

                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                              • HUnafld057_1 HUnafld057_1 tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                              • HUnafld057_1 HUnafld057_1 tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                • HUnafld057_1 HUnafld057_1 tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                • HUnafld057_1 HUnafld057_1 tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                              HUnafld057_1
                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772550
sample_title: HUnafld057_1
source_name: HUnafld057_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 68; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                              GSM5772551

                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                              HUnafld058_1

                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                    • HUnafld058_1 HUnafld058_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                    • HUnafld058_1 HUnafld058_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                      • HUnafld058_1 HUnafld058_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                      • HUnafld058_1 HUnafld058_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                    HUnafld058_1
                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772551
sample_title: HUnafld058_1
source_name: HUnafld058_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                    GSM5772552

                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                    HUnafld059_1

                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                          • HUnafld059_1 HUnafld059_1 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                          • HUnafld059_1 HUnafld059_1 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                            • HUnafld059_1 HUnafld059_1 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                            • HUnafld059_1 HUnafld059_1 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                          HUnafld059_1
                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772552
sample_title: HUnafld059_1
source_name: HUnafld059_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                          GSM5772553

                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                          HUnafld060_1

                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                • HUnafld060_1 HUnafld060_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                • HUnafld060_1 HUnafld060_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                  • HUnafld060_1 HUnafld060_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                  • HUnafld060_1 HUnafld060_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                HUnafld060_1
                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772553
sample_title: HUnafld060_1
source_name: HUnafld060_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                GSM5772554

                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                HUnafld061

                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                      • HUnafld061 HUnafld061 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                      • HUnafld061 HUnafld061 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                        • HUnafld061 HUnafld061 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                        • HUnafld061 HUnafld061 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                      HUnafld061
                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772554
sample_title: HUnafld061
source_name: HUnafld061
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                      GSM5772555

                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                      HUnafld062

                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                            • HUnafld062 HUnafld062 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                            • HUnafld062 HUnafld062 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                              • HUnafld062 HUnafld062 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                              • HUnafld062 HUnafld062 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                            HUnafld062
                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772555
sample_title: HUnafld062
source_name: HUnafld062
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                            GSM5772556

                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                            HUnafld063_1

                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                  • HUnafld063_1 HUnafld063_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                  • HUnafld063_1 HUnafld063_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                    • HUnafld063_1 HUnafld063_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                    • HUnafld063_1 HUnafld063_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                  HUnafld063_1
                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772556
sample_title: HUnafld063_1
source_name: HUnafld063_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                  GSM5772557

                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                  HUnafld064_1

                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                        • HUnafld064_1 HUnafld064_1 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                        • HUnafld064_1 HUnafld064_1 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                          • HUnafld064_1 HUnafld064_1 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                          • HUnafld064_1 HUnafld064_1 tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                        HUnafld064_1
                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772557
sample_title: HUnafld064_1
source_name: HUnafld064_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                        GSM5772558

                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                        HUnafld065

                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                              • HUnafld065 HUnafld065 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                              • HUnafld065 HUnafld065 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                • HUnafld065 HUnafld065 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                • HUnafld065 HUnafld065 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                              HUnafld065
                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772558
sample_title: HUnafld065
source_name: HUnafld065
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                              GSM5772559

                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                              HUnafld066_1

                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                    • HUnafld066_1 HUnafld066_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                    • HUnafld066_1 HUnafld066_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                      • HUnafld066_1 HUnafld066_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                      • HUnafld066_1 HUnafld066_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                    HUnafld066_1
                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772559
sample_title: HUnafld066_1
source_name: HUnafld066_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: male; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                    GSM5772560

                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                    HUnafld067_1

                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                          • HUnafld067_1 HUnafld067_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                          • HUnafld067_1 HUnafld067_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                            • HUnafld067_1 HUnafld067_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                            • HUnafld067_1 HUnafld067_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                          HUnafld067_1
                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772560
sample_title: HUnafld067_1
source_name: HUnafld067_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                          GSM5772561

                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                          HUnafld068_1

                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                • HUnafld068_1 HUnafld068_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                • HUnafld068_1 HUnafld068_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld068_1 HUnafld068_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld068_1 HUnafld068_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                HUnafld068_1
                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772561
sample_title: HUnafld068_1
source_name: HUnafld068_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                GSM5772562

                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                HUnafld069_1

                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld069_1 HUnafld069_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld069_1 HUnafld069_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld069_1 HUnafld069_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld069_1 HUnafld069_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                      HUnafld069_1
                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772562
sample_title: HUnafld069_1
source_name: HUnafld069_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                      GSM5772563

                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                      HUnafld070_1

                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld070_1 HUnafld070_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld070_1 HUnafld070_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld070_1 HUnafld070_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld070_1 HUnafld070_1 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                            HUnafld070_1
                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772563
sample_title: HUnafld070_1
source_name: HUnafld070_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                            GSM5772564

                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                            HUnafld071_1

                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld071_1 HUnafld071_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld071_1 HUnafld071_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld071_1 HUnafld071_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld071_1 HUnafld071_1 tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld071_1
                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772564
sample_title: HUnafld071_1
source_name: HUnafld071_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 50; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772565

                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld072_1

                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld072_1 HUnafld072_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld072_1 HUnafld072_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld072_1 HUnafld072_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld072_1 HUnafld072_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld072_1
                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772565
sample_title: HUnafld072_1
source_name: HUnafld072_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772566

                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld073

                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld073 HUnafld073 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld073 HUnafld073 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld073 HUnafld073 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld073 HUnafld073 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld073
                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772566
sample_title: HUnafld073
source_name: HUnafld073
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772567

                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld074_1

                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld074_1 HUnafld074_1 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld074_1 HUnafld074_1 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld074_1 HUnafld074_1 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld074_1 HUnafld074_1 tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld074_1
                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772567
sample_title: HUnafld074_1
source_name: HUnafld074_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772568

                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld075_1

                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld075_1 HUnafld075_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld075_1 HUnafld075_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld075_1 HUnafld075_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld075_1 HUnafld075_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld075_1
                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772568
sample_title: HUnafld075_1
source_name: HUnafld075_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772569

                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld076_1

                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld076_1 HUnafld076_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld076_1 HUnafld076_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld076_1 HUnafld076_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld076_1 HUnafld076_1 tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld076_1
                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772569
sample_title: HUnafld076_1
source_name: HUnafld076_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 59; Sex: female; fibrosis stage: 3; nafld activity score: 8; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772570

                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld077_1

                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld077_1 HUnafld077_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld077_1 HUnafld077_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld077_1 HUnafld077_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld077_1 HUnafld077_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld077_1
                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772570
sample_title: HUnafld077_1
source_name: HUnafld077_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772571

                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld078_1

                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld078_1 HUnafld078_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld078_1 HUnafld078_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld078_1 HUnafld078_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld078_1 HUnafld078_1 tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld078_1
                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772571
sample_title: HUnafld078_1
source_name: HUnafld078_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 53; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772572

                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld079_1

                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld079_1 HUnafld079_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld079_1 HUnafld079_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld079_1 HUnafld079_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld079_1 HUnafld079_1 tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld079_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772572
sample_title: HUnafld079_1
source_name: HUnafld079_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 60; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772573

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld080_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld080_1 HUnafld080_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld080_1 HUnafld080_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld080_1 HUnafld080_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld080_1 HUnafld080_1 tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld080_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772573
sample_title: HUnafld080_1
source_name: HUnafld080_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 46; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772574

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld081_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld081_1 HUnafld081_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld081_1 HUnafld081_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld081_1 HUnafld081_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld081_1 HUnafld081_1 tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld081_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772574
sample_title: HUnafld081_1
source_name: HUnafld081_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 37; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772575

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld082_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld082_1 HUnafld082_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld082_1 HUnafld082_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld082_1 HUnafld082_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld082_1 HUnafld082_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld082_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772575
sample_title: HUnafld082_1
source_name: HUnafld082_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772576

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld083

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld083 HUnafld083 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld083 HUnafld083 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld083 HUnafld083 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld083 HUnafld083 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld083
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772576
sample_title: HUnafld083
source_name: HUnafld083
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772577

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld084

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld084 HUnafld084 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld084 HUnafld084 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld084 HUnafld084 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld084 HUnafld084 tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld084
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772577
sample_title: HUnafld084
source_name: HUnafld084
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 42; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772578

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld085_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld085_1 HUnafld085_1 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld085_1 HUnafld085_1 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld085_1 HUnafld085_1 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld085_1 HUnafld085_1 tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld085_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772578
sample_title: HUnafld085_1
source_name: HUnafld085_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 32; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772579

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld086

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld086 HUnafld086 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld086 HUnafld086 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld086 HUnafld086 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld086 HUnafld086 tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld086
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772579
sample_title: HUnafld086
source_name: HUnafld086
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772580

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld087_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld087_1 HUnafld087_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld087_1 HUnafld087_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld087_1 HUnafld087_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld087_1 HUnafld087_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld087_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772580
sample_title: HUnafld087_1
source_name: HUnafld087_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772581

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld088_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld088_1 HUnafld088_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld088_1 HUnafld088_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld088_1 HUnafld088_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld088_1 HUnafld088_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld088_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772581
sample_title: HUnafld088_1
source_name: HUnafld088_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772582

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld089_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld089_1 HUnafld089_1 tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld089_1 HUnafld089_1 tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld089_1 HUnafld089_1 tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld089_1 HUnafld089_1 tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld089_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772582
sample_title: HUnafld089_1
source_name: HUnafld089_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 58; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772583

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld090_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld090_1 HUnafld090_1 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld090_1 HUnafld090_1 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld090_1 HUnafld090_1 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld090_1 HUnafld090_1 tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld090_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772583
sample_title: HUnafld090_1
source_name: HUnafld090_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 31; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772584

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld091_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld091_1 HUnafld091_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld091_1 HUnafld091_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld091_1 HUnafld091_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld091_1 HUnafld091_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld091_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772584
sample_title: HUnafld091_1
source_name: HUnafld091_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772585

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld092_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld092_1 HUnafld092_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld092_1 HUnafld092_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld092_1 HUnafld092_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld092_1 HUnafld092_1 tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld092_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772585
sample_title: HUnafld092_1
source_name: HUnafld092_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 69; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772586

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld093_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld093_1 HUnafld093_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld093_1 HUnafld093_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld093_1 HUnafld093_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld093_1 HUnafld093_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld093_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772586
sample_title: HUnafld093_1
source_name: HUnafld093_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772587

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld094_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld094_1 HUnafld094_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld094_1 HUnafld094_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld094_1 HUnafld094_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld094_1 HUnafld094_1 tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld094_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772587
sample_title: HUnafld094_1
source_name: HUnafld094_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 63; Sex: male; fibrosis stage: 2; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772588

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld095_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld095_1 HUnafld095_1 tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld095_1 HUnafld095_1 tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld095_1 HUnafld095_1 tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld095_1 HUnafld095_1 tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld095_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772588
sample_title: HUnafld095_1
source_name: HUnafld095_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 79; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772589

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld096_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld096_1 HUnafld096_1 tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld096_1 HUnafld096_1 tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld096_1 HUnafld096_1 tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld096_1 HUnafld096_1 tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld096_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772589
sample_title: HUnafld096_1
source_name: HUnafld096_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 34; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772590

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld097_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld097_1 HUnafld097_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld097_1 HUnafld097_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld097_1 HUnafld097_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld097_1 HUnafld097_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld097_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772590
sample_title: HUnafld097_1
source_name: HUnafld097_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772591

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld098_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld098_1 HUnafld098_1 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld098_1 HUnafld098_1 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld098_1 HUnafld098_1 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld098_1 HUnafld098_1 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld098_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772591
sample_title: HUnafld098_1
source_name: HUnafld098_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772592

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld099_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld099_1 HUnafld099_1 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld099_1 HUnafld099_1 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld099_1 HUnafld099_1 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld099_1 HUnafld099_1 tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld099_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772592
sample_title: HUnafld099_1
source_name: HUnafld099_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 47; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772593

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld100

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld100 HUnafld100 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld100 HUnafld100 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld100 HUnafld100 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld100 HUnafld100 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld100
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772593
sample_title: HUnafld100
source_name: HUnafld100
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: male; fibrosis stage: 1; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772594

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld101_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld101_1 HUnafld101_1 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld101_1 HUnafld101_1 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld101_1 HUnafld101_1 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld101_1 HUnafld101_1 tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld101_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772594
sample_title: HUnafld101_1
source_name: HUnafld101_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772595

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld102_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld102_1 HUnafld102_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld102_1 HUnafld102_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld102_1 HUnafld102_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld102_1 HUnafld102_1 tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld102_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772595
sample_title: HUnafld102_1
source_name: HUnafld102_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 73; Sex: female; fibrosis stage: 2; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772596

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld103_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld103_1 HUnafld103_1 tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld103_1 HUnafld103_1 tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld103_1 HUnafld103_1 tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld103_1 HUnafld103_1 tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld103_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772596
sample_title: HUnafld103_1
source_name: HUnafld103_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 35; Sex: male; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772597

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld104

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld104 HUnafld104 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld104 HUnafld104 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld104 HUnafld104 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld104 HUnafld104 tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld104
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772597
sample_title: HUnafld104
source_name: HUnafld104
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 54; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772598

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld105

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld105 HUnafld105 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld105 HUnafld105 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld105 HUnafld105 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld105 HUnafld105 tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld105
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772598
sample_title: HUnafld105
source_name: HUnafld105
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772599

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld106_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld106_1 HUnafld106_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld106_1 HUnafld106_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld106_1 HUnafld106_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld106_1 HUnafld106_1 tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld106_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772599
sample_title: HUnafld106_1
source_name: HUnafld106_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 74; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772600

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld107_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld107_1 HUnafld107_1 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld107_1 HUnafld107_1 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld107_1 HUnafld107_1 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld107_1 HUnafld107_1 tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld107_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772600
sample_title: HUnafld107_1
source_name: HUnafld107_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 43; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772601

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld108_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld108_1 HUnafld108_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld108_1 HUnafld108_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld108_1 HUnafld108_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld108_1 HUnafld108_1 tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld108_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772601
sample_title: HUnafld108_1
source_name: HUnafld108_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 48; Sex: female; fibrosis stage: 1; nafld activity score: 6; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772602

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld109_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld109_1 HUnafld109_1 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld109_1 HUnafld109_1 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld109_1 HUnafld109_1 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld109_1 HUnafld109_1 tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld109_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772602
sample_title: HUnafld109_1
source_name: HUnafld109_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772603

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld110_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld110_1 HUnafld110_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld110_1 HUnafld110_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld110_1 HUnafld110_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld110_1 HUnafld110_1 tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld110_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772603
sample_title: HUnafld110_1
source_name: HUnafld110_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772604

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld111_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld111_1 HUnafld111_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld111_1 HUnafld111_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld111_1 HUnafld111_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld111_1 HUnafld111_1 tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld111_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772604
sample_title: HUnafld111_1
source_name: HUnafld111_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 33; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772605

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld112_1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld112_1 HUnafld112_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld112_1 HUnafld112_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld112_1 HUnafld112_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld112_1 HUnafld112_1 tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: hig...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld112_1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772605
sample_title: HUnafld112_1
source_name: HUnafld112_1
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 57; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: high-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772606

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld113

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld113 HUnafld113 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld113 HUnafld113 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld113 HUnafld113 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld113 HUnafld113 tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld113
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772606
sample_title: HUnafld113
source_name: HUnafld113
characteristics: tissue: Liver; biopsy: 1st biopsy; age: 55; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: low-risk

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772607

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld035_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld035_2 HUnafld035_2 tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld035_2 HUnafld035_2 tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld035_2 HUnafld035_2 tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld035_2 HUnafld035_2 tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld035_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772607
sample_title: HUnafld035_2
source_name: HUnafld035_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 23; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772608

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld038_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld038_2 HUnafld038_2 tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld038_2 HUnafld038_2 tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld038_2 HUnafld038_2 tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld038_2 HUnafld038_2 tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld038_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772608
sample_title: HUnafld038_2
source_name: HUnafld038_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 44; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772609

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld039_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld039_2 HUnafld039_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld039_2 HUnafld039_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld039_2 HUnafld039_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld039_2 HUnafld039_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld039_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772609
sample_title: HUnafld039_2
source_name: HUnafld039_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: male; fibrosis stage: 2; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772610

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld046_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld046_2 HUnafld046_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld046_2 HUnafld046_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld046_2 HUnafld046_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld046_2 HUnafld046_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld046_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772610
sample_title: HUnafld046_2
source_name: HUnafld046_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772611

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld047_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld047_2 HUnafld047_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld047_2 HUnafld047_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld047_2 HUnafld047_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld047_2 HUnafld047_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld047_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772611
sample_title: HUnafld047_2
source_name: HUnafld047_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: male; fibrosis stage: 1; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772612

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld048_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld048_2 HUnafld048_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld048_2 HUnafld048_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld048_2 HUnafld048_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld048_2 HUnafld048_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld048_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772612
sample_title: HUnafld048_2
source_name: HUnafld048_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772613

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld049_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld049_2 HUnafld049_2 tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld049_2 HUnafld049_2 tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld049_2 HUnafld049_2 tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld049_2 HUnafld049_2 tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld049_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772613
sample_title: HUnafld049_2
source_name: HUnafld049_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 59; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772614

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld050_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld050_2 HUnafld050_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld050_2 HUnafld050_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld050_2 HUnafld050_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld050_2 HUnafld050_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld050_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772614
sample_title: HUnafld050_2
source_name: HUnafld050_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772615

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld052_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld052_2 HUnafld052_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld052_2 HUnafld052_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld052_2 HUnafld052_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld052_2 HUnafld052_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld052_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772615
sample_title: HUnafld052_2
source_name: HUnafld052_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: male; fibrosis stage: 1; nafld activity score: 1; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772616

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld053_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld053_2 HUnafld053_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld053_2 HUnafld053_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld053_2 HUnafld053_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld053_2 HUnafld053_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld053_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772616
sample_title: HUnafld053_2
source_name: HUnafld053_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772617

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld054_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld054_2 HUnafld054_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld054_2 HUnafld054_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld054_2 HUnafld054_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld054_2 HUnafld054_2 tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld054_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772617
sample_title: HUnafld054_2
source_name: HUnafld054_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 48; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772618

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld056_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld056_2 HUnafld056_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld056_2 HUnafld056_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld056_2 HUnafld056_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld056_2 HUnafld056_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld056_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772618
sample_title: HUnafld056_2
source_name: HUnafld056_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772619

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld057_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld057_2 HUnafld057_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld057_2 HUnafld057_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld057_2 HUnafld057_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld057_2 HUnafld057_2 tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld057_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772619
sample_title: HUnafld057_2
source_name: HUnafld057_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 71; Sex: female; fibrosis stage: 3; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772620

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld058_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld058_2 HUnafld058_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld058_2 HUnafld058_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld058_2 HUnafld058_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld058_2 HUnafld058_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld058_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772620
sample_title: HUnafld058_2
source_name: HUnafld058_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772621

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld059_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld059_2 HUnafld059_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld059_2 HUnafld059_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld059_2 HUnafld059_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld059_2 HUnafld059_2 tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld059_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772621
sample_title: HUnafld059_2
source_name: HUnafld059_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 64; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772622

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld060_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld060_2 HUnafld060_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld060_2 HUnafld060_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld060_2 HUnafld060_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld060_2 HUnafld060_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld060_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772622
sample_title: HUnafld060_2
source_name: HUnafld060_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772623

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld063_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld063_2 HUnafld063_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld063_2 HUnafld063_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld063_2 HUnafld063_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld063_2 HUnafld063_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld063_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772623
sample_title: HUnafld063_2
source_name: HUnafld063_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772624

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld064_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld064_2 HUnafld064_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld064_2 HUnafld064_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld064_2 HUnafld064_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld064_2 HUnafld064_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld064_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772624
sample_title: HUnafld064_2
source_name: HUnafld064_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772625

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld066_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld066_2 HUnafld066_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld066_2 HUnafld066_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld066_2 HUnafld066_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld066_2 HUnafld066_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld066_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772625
sample_title: HUnafld066_2
source_name: HUnafld066_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772626

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld067_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld067_2 HUnafld067_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld067_2 HUnafld067_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld067_2 HUnafld067_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld067_2 HUnafld067_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld067_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772626
sample_title: HUnafld067_2
source_name: HUnafld067_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772627

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld068_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld068_2 HUnafld068_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld068_2 HUnafld068_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld068_2 HUnafld068_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld068_2 HUnafld068_2 tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld068_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772627
sample_title: HUnafld068_2
source_name: HUnafld068_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 61; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772628

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld069_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld069_2 HUnafld069_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld069_2 HUnafld069_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld069_2 HUnafld069_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld069_2 HUnafld069_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld069_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772628
sample_title: HUnafld069_2
source_name: HUnafld069_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772629

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld070_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld070_2 HUnafld070_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld070_2 HUnafld070_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld070_2 HUnafld070_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld070_2 HUnafld070_2 tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld070_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772629
sample_title: HUnafld070_2
source_name: HUnafld070_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 57; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772630

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld071_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld071_2 HUnafld071_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld071_2 HUnafld071_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld071_2 HUnafld071_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld071_2 HUnafld071_2 tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld071_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772630
sample_title: HUnafld071_2
source_name: HUnafld071_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 53; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772631

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld072_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld072_2 HUnafld072_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld072_2 HUnafld072_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld072_2 HUnafld072_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld072_2 HUnafld072_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld072_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772631
sample_title: HUnafld072_2
source_name: HUnafld072_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772632

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld074_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld074_2 HUnafld074_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld074_2 HUnafld074_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld074_2 HUnafld074_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld074_2 HUnafld074_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld074_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772632
sample_title: HUnafld074_2
source_name: HUnafld074_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772633

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld075_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld075_2 HUnafld075_2 tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld075_2 HUnafld075_2 tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld075_2 HUnafld075_2 tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld075_2 HUnafld075_2 tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld075_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772633
sample_title: HUnafld075_2
source_name: HUnafld075_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 47; Sex: male; fibrosis stage: 1; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772634

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld076_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld076_2 HUnafld076_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld076_2 HUnafld076_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld076_2 HUnafld076_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld076_2 HUnafld076_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld076_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772634
sample_title: HUnafld076_2
source_name: HUnafld076_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772635

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld077_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld077_2 HUnafld077_2 tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld077_2 HUnafld077_2 tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld077_2 HUnafld077_2 tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld077_2 HUnafld077_2 tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld077_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772635
sample_title: HUnafld077_2
source_name: HUnafld077_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 40; Sex: female; fibrosis stage: 2; nafld activity score: 2; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772636

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld078_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld078_2 HUnafld078_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld078_2 HUnafld078_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld078_2 HUnafld078_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld078_2 HUnafld078_2 tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld078_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772636
sample_title: HUnafld078_2
source_name: HUnafld078_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 54; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772637

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld079_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld079_2 HUnafld079_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld079_2 HUnafld079_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld079_2 HUnafld079_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld079_2 HUnafld079_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld079_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772637
sample_title: HUnafld079_2
source_name: HUnafld079_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772638

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld080_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld080_2 HUnafld080_2 tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld080_2 HUnafld080_2 tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld080_2 HUnafld080_2 tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld080_2 HUnafld080_2 tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld080_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772638
sample_title: HUnafld080_2
source_name: HUnafld080_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 41; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772639

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld081_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld081_2 HUnafld081_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld081_2 HUnafld081_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld081_2 HUnafld081_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld081_2 HUnafld081_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld081_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772639
sample_title: HUnafld081_2
source_name: HUnafld081_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772640

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld082_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld082_2 HUnafld082_2 tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld082_2 HUnafld082_2 tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld082_2 HUnafld082_2 tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld082_2 HUnafld082_2 tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld082_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772640
sample_title: HUnafld082_2
source_name: HUnafld082_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 50; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772641

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld085_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld085_2 HUnafld085_2 tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld085_2 HUnafld085_2 tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld085_2 HUnafld085_2 tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld085_2 HUnafld085_2 tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld085_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772641
sample_title: HUnafld085_2
source_name: HUnafld085_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 33; Sex: male; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772642

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld087_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld087_2 HUnafld087_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld087_2 HUnafld087_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld087_2 HUnafld087_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld087_2 HUnafld087_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld087_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772642
sample_title: HUnafld087_2
source_name: HUnafld087_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772643

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld088_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld088_2 HUnafld088_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld088_2 HUnafld088_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld088_2 HUnafld088_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld088_2 HUnafld088_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld088_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772643
sample_title: HUnafld088_2
source_name: HUnafld088_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772644

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld089_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld089_2 HUnafld089_2 tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld089_2 HUnafld089_2 tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld089_2 HUnafld089_2 tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld089_2 HUnafld089_2 tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld089_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772644
sample_title: HUnafld089_2
source_name: HUnafld089_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 60; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772645

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld090_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld090_2 HUnafld090_2 tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld090_2 HUnafld090_2 tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld090_2 HUnafld090_2 tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld090_2 HUnafld090_2 tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld090_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772645
sample_title: HUnafld090_2
source_name: HUnafld090_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 35; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772646

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld091_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld091_2 HUnafld091_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld091_2 HUnafld091_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld091_2 HUnafld091_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld091_2 HUnafld091_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld091_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772646
sample_title: HUnafld091_2
source_name: HUnafld091_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772647

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld092_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld092_2 HUnafld092_2 tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld092_2 HUnafld092_2 tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld092_2 HUnafld092_2 tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld092_2 HUnafld092_2 tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld092_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772647
sample_title: HUnafld092_2
source_name: HUnafld092_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 76; Sex: female; fibrosis stage: 1; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772648

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld093_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld093_2 HUnafld093_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld093_2 HUnafld093_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld093_2 HUnafld093_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld093_2 HUnafld093_2 tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld093_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772648
sample_title: HUnafld093_2
source_name: HUnafld093_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 62; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772649

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld094_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld094_2 HUnafld094_2 tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld094_2 HUnafld094_2 tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld094_2 HUnafld094_2 tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld094_2 HUnafld094_2 tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld094_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772649
sample_title: HUnafld094_2
source_name: HUnafld094_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 66; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772650

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld095_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld095_2 HUnafld095_2 tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld095_2 HUnafld095_2 tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld095_2 HUnafld095_2 tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld095_2 HUnafld095_2 tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld095_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772650
sample_title: HUnafld095_2
source_name: HUnafld095_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 83; Sex: female; fibrosis stage: 4; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772651

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld096_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld096_2 HUnafld096_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld096_2 HUnafld096_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld096_2 HUnafld096_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld096_2 HUnafld096_2 tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld096_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772651
sample_title: HUnafld096_2
source_name: HUnafld096_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 37; Sex: male; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772652

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld097_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld097_2 HUnafld097_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld097_2 HUnafld097_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld097_2 HUnafld097_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld097_2 HUnafld097_2 tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld097_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772652
sample_title: HUnafld097_2
source_name: HUnafld097_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 39; Sex: male; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772653

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld098_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld098_2 HUnafld098_2 tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld098_2 HUnafld098_2 tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld098_2 HUnafld098_2 tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld098_2 HUnafld098_2 tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld098_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772653
sample_title: HUnafld098_2
source_name: HUnafld098_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 43; Sex: male; fibrosis stage: 3; nafld activity score: 7; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772654

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld099_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld099_2 HUnafld099_2 tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld099_2 HUnafld099_2 tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld099_2 HUnafld099_2 tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld099_2 HUnafld099_2 tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld099_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772654
sample_title: HUnafld099_2
source_name: HUnafld099_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 49; Sex: female; fibrosis stage: 2; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772655

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld101_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld101_2 HUnafld101_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld101_2 HUnafld101_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld101_2 HUnafld101_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld101_2 HUnafld101_2 tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld101_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772655
sample_title: HUnafld101_2
source_name: HUnafld101_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 65; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772656

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld102_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld102_2 HUnafld102_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld102_2 HUnafld102_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld102_2 HUnafld102_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld102_2 HUnafld102_2 tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld102_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772656
sample_title: HUnafld102_2
source_name: HUnafld102_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 75; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM5772657

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld103_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld103_2 HUnafld103_2 tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld103_2 HUnafld103_2 tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld103_2 HUnafld103_2 tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld103_2 HUnafld103_2 tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld103_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM5772657
sample_title: HUnafld103_2
source_name: HUnafld103_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 38; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM5772658

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                HUnafld106_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld106_2 HUnafld106_2 tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld106_2 HUnafld106_2 tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld106_2 HUnafld106_2 tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld106_2 HUnafld106_2 tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld106_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM5772658
sample_title: HUnafld106_2
source_name: HUnafld106_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 77; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM5772659

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      HUnafld107_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld107_2 HUnafld107_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld107_2 HUnafld107_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld107_2 HUnafld107_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld107_2 HUnafld107_2 tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld107_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM5772659
sample_title: HUnafld107_2
source_name: HUnafld107_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 46; Sex: female; fibrosis stage: 3; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM5772660

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            HUnafld108_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld108_2 HUnafld108_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • HUnafld108_2 HUnafld108_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld108_2 HUnafld108_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld108_2 HUnafld108_2 tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld108_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM5772660
sample_title: HUnafld108_2
source_name: HUnafld108_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 51; Sex: female; fibrosis stage: 2; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM5772661

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  HUnafld109_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld109_2 HUnafld109_2 tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • HUnafld109_2 HUnafld109_2 tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld109_2 HUnafld109_2 tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld109_2 HUnafld109_2 tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld109_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM5772661
sample_title: HUnafld109_2
source_name: HUnafld109_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 73; Sex: female; fibrosis stage: 3; nafld activity score: 5; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM5772662

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        HUnafld110_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld110_2 HUnafld110_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • HUnafld110_2 HUnafld110_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld110_2 HUnafld110_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • HUnafld110_2 HUnafld110_2 tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld110_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM5772662
sample_title: HUnafld110_2
source_name: HUnafld110_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 63; Sex: female; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM5772663

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              HUnafld111_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld111_2 HUnafld111_2 tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • HUnafld111_2 HUnafld111_2 tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld111_2 HUnafld111_2 tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • HUnafld111_2 HUnafld111_2 tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld111_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM5772663
sample_title: HUnafld111_2
source_name: HUnafld111_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 36; Sex: male; fibrosis stage: 2; nafld activity score: 4; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM5772664

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    HUnafld112_2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. specimen category excludes: Biofluid — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld112_2 HUnafld112_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • HUnafld112_2 HUnafld112_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld112_2 HUnafld112_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • HUnafld112_2 HUnafld112_2 tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          HUnafld112_2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM5772664
sample_title: HUnafld112_2
source_name: HUnafld112_2
characteristics: tissue: Liver; biopsy: 2nd biopsy; age: 58; Sex: female; fibrosis stage: 3; nafld activity score: 3; pls-nafld-based risk prediction at 1st biopsy: NA

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded samples (0)

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          No excluded samples.