Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

46 case / 13 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: bulk RNA-seq
Organism: Homo sapiens
Whole-study samples: 59 samples
Specimen: Tissue
Reported/interpreted study design: Disease/model vs control Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Kim K, Park S, Lee Y
Contact name: SoJung Park
Submission date: 2023-03-14
Last update: 2023-09-06
Organization: Ulsan medical university
Department: Not available
Public date: 2023-09-06
Experiment types: Expression profiling by high throughput sequencing
Platforms: GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Series type: Series
SubSeries: Not available
BioProject: PRJNA944790

Summary

In Crohn's disease, creeping fat is the characteristic expansion of mesenteric adipose tissue wrapping around the inflamed intestine. Through a comparative transcriptomic analysis of creeping fat and normal-looking mesenteric adipose tissues from patients with Crohn's disease and non-Crohn's disease, we found that a dynamic transcriptional and cell compositional change occurs during the progression from non-Crohn's disease to Crohn's disease, and finally to creeping fat.

Overall design

Comparative gene expression profiling analysis of RNA-seq data for patients with CD CF, CD MAT and Con MAT. **Submitter declares that the raw data cannot be deposited due to hospital policy**

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 59 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Planned source for curated expression experiment links.	No match found
PubMed	Primary GEO citations and related PubMed articles that mention this dataset. 1 linked publication 1 DOI Primary publication Transcriptomic Profiling and Cellular Composition of Creeping Fat in Crohn's disease. Journal of Crohn's & colitis, 2024 PubMed DOI	Available

Metadata Quality Components

Persisted metadata quality

100 pts

Clarity: 100%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review

97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Standard analyst review

Proceed only after the analyst confirms grouping, exclusions, and source files.

By Siftome standards, no expert review was triggered.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Disease context Crohn's disease, colorectal cancer, inflammatory bowel disease, ulcerative colitis Disease context came from Normalization rules.
Likely case group Crohn's disease 46 samples
Likely control group Control 13 samples

Ranking Facts

Supporting evidence

Comparison: Disease/model vs control. Specimen: Tissue. Comparison suitability: 0%.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Colorectal cancer, Crohn's disease, Inflammatory bowel disease, Ulcerative colitis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 37594364.
Publication context: Transcriptomic Profiling and Cellular Composition of Creeping Fat in Crohn's disease.. Journal of Crohn's & colitis, 2024. PMID 37594364. DOI 10.1093/ecco-jcc/jjad141.

Cautions

Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
Overall score capped because comparison suitability is weak for the selected search intent.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis.

Normalized Fields

83 fields

Field Value Source Derived by Confidence Evidence Reason

assay_type bulk RNA-seq GSE227376 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence bulk rna-seq dataset_accession: GSE227376 dataset_title: Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease org... keyword match keyword match: bulk rna-seq

disease Crohn's disease GSE227376 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease dataset_accession: GSE227376 dataset_title: Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease org... controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099414 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP42, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099415 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP45, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099416 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP48, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099417 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP50, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099418 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP51, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099419 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP52, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099420 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP54, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099421 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP56, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099422 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP57, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099423 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP58, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099424 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP60, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099425 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP61, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099426 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP62, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099427 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP63, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099428 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP65, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099429 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP67, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099430 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP68, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099431 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP69, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099432 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP71, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099433 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP72, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099434 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP74, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099435 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP77, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099436 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FP82, CD participants, pair sample, Creeping fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099437 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN42, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099438 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN45, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099439 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN48, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099440 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN50, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099441 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN51, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099442 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN52, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099443 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN54, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099444 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN56, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099445 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN57, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099446 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN58, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099447 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN60, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099448 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN61, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099449 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN62, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099450 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN63, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099451 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN65, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099452 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN67, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099453 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN68, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099454 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN69, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099455 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN71, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099456 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN72, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099457 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN74, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099458 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN77, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease Crohn's disease GSM7099459 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence Crohn's disease FN82, CD participants, pair sample, CD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Crohn's disease controlled vocabulary controlled vocabulary disease match: Crohn's disease

disease ulcerative colitis GSM7099460 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis UC100, Control participants, control sample, UC mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Ulcerative colitis controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease ulcerative colitis GSM7099461 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis UC92, Control participants, control sample, UC mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Ulcerative colitis controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease ulcerative colitis GSM7099462 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence ulcerative colitis UC94, Control participants, control sample, UC mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Ulcerative colitis controlled vocabulary controlled vocabulary disease match: ulcerative colitis

disease colorectal cancer GSM7099463 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN02, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099463 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN02, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099464 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN03, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099464 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN03, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099465 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN04, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099465 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN04, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099466 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN05, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099466 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN05, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099467 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN09, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099467 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN09, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099468 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN11, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099468 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN11, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099469 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN01, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099469 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN01, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099470 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN06, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099470 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN06, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099471 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN07, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099471 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN07, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

disease colorectal cancer GSM7099472 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence colon cancer CFN12, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: colon cancer

disease inflammatory bowel disease GSM7099472 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence ibd CFN12, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary disease match: ibd

organism Homo sapiens GSE227376 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence homo sapiens dataset_accession: GSE227376 dataset_title: Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease org... keyword match keyword match: homo sapiens

tissue intestine GSE227376 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence intestine dataset_accession: GSE227376 dataset_title: Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease org... controlled vocabulary controlled vocabulary tissue match: intestine

tissue colon GSM7099463 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN02, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099464 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN03, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099465 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN04, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099466 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN05, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099467 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN09, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099468 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN11, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099469 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN01, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099470 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN06, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Male; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099471 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN07, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

tissue colon GSM7099472 Runtime Siftome inference UNRESOLVED / UNREVIEWED low confidence colon CFN12, Control participants, control sample, non-IBD mesenteric fat Mesenteric fat tissue: Mesenteric fat; Sex: Female; disease: Colon cancer controlled vocabulary controlled vocabulary tissue match: colon

Sample Group Preview

59 rows shown Show Hide

Study totals: Case 46 | Control 13 | Unassigned 0 | Excluded 0 | Ambiguous 0 59 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Crohn's disease	Case	GSM7099414	FP42, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099415	FP45, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099416	FP48, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099417	FP50, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099418	FP51, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099419	FP52, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099420	FP54, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099421	FP56, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099422	FP57, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099423	FP58, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099424	FP60, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099425	FP61, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099426	FP62, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099427	FP63, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099428	FP65, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099429	FP67, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099430	FP68, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099431	FP69, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099432	FP71, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099433	FP72, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099434	FP74, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099435	FP77, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099436	FP82, CD participants, pair sample, Creeping fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099437	FN42, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099438	FN45, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099439	FN48, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099440	FN50, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099441	FN51, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099442	FN52, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099443	FN54, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099444	FN56, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099445	FN57, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099446	FN58, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099447	FN60, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099448	FN61, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099449	FN62, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099450	FN63, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099451	FN65, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099452	FN67, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099453	FN68, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099454	FN69, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099455	FN71, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099456	FN72, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099457	FN74, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099458	FN77, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Crohn's disease	Case marker detected.
Crohn's disease	Case	GSM7099459	FN82, CD participants, pair sample, CD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Crohn's disease	Case marker detected.
Control	Control	GSM7099460	UC100, Control participants, control sample, UC mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Ulcerative colitis	Sample-local control marker detected.
Control	Control	GSM7099461	UC92, Control participants, control sample, UC mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Ulcerative colitis	Sample-local control marker detected.
Control	Control	GSM7099462	UC94, Control participants, control sample, UC mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Ulcerative colitis	Sample-local control marker detected.
Control	Control	GSM7099463	CFN02, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099464	CFN03, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099465	CFN04, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099466	CFN05, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099467	CFN09, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099468	CFN11, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099469	CFN01, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099470	CFN06, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Male; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099471	CFN07, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.
Control	Control	GSM7099472	CFN12, Control participants, control sample, non-IBD mesenteric fat	Mesenteric fat Tissue: Mesenteric fat; Sex: Female; Disease: Colon cancer	Sample-local control marker detected.

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