GSE24287

Differential early pathogenic changes in human ileal gene expression in Crohn's disease and ulcerative colitis

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

74 case / 25 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source
GEO
Assay
microarray
Organism
Homo sapiens
Whole-study samples
99 samples
Specimen
Tissue
Reported/interpreted study design
Disease/model vs control Design classification does not establish patient pairs.
Comparison type
Tumor vs normal
Contributors
Zhang T, Li E
Contact name
Tianyi Zhang
Submission date
2010-09-22
Last update
2019-10-31
Organization
Stony Brook University
Department
Not available
Public date
2010-09-26
Experiment types
Expression profiling by array
Platforms
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Series type
Series
SubSeries
Not available
BioProject
PRJNA129995

Summary

The aim of this study is to identify early pathogenic changes in ileal gene expression that precede the development of macroscopic disease in inflammatory bowel diseases (IBDs). We focused on two IBD phenotypes that were unlikely to overlap: 1) ileal Crohn’s disease (CD) patients undergoing initial ileocolic resection of diseased ileum; and 2) ulcerative colitis (UC) patients undergoing total colectomy. The Control patients were those patients without IBD undergoing initial right hemicolectomy or total colectomy.

Overall design

In order to identify early pathogenic changes in the human ileum in inflammatory bowel diseases, we analyzed 99 two-color whole human genome expression profiles (Agilent 4410A) of a test human ileal cRNA probe vs. a common reference human ileal RNA from a Control patient (N17). A minimum of four biopsies were taken from the macroscopically disease-unaffected proximal ileal margin of freshly resected specimens from 47 ileal Crohn's disease patients undergoing initial ileocolic resection, 27 ulcerative colitis patients undergoing total colectomy and 25 Control patients undergoing either right hemicolectomy or total colectomy. The test and common reference probes were synthesized using the Agilent Low Input Linear Amplification Kit. Hybridization was carried out in DNA hybridization chambers, washed and scanned on an Axon GenePix 4000B scanner. The preprocessing, filtering and normalization of the array data was carried out using the R package LIMMA.

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
99 GSM samples
 Primary source
recount3

Planned trusted source for processed count availability.

 No match found
Expression Atlas

Planned source for curated expression experiment links.

 No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

5 linked publications 5 DOIs

Primary publication

  1. Host genes related to paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition. PloS one, 2012
  2. An ileal Crohn's disease gene signature based on whole human genome expression profiles of disease unaffected ileal mucosal biopsies. PloS one, 2012

Related publications

  1. Identifying candidate genes for discrimination of ulcerative colitis and Crohn's disease. Molecular biology reports, 2014
  2. Comprehensive analysis of monocyte palmitoylation-related genes IFITM3 and CCL3-CCR5 axis in crohn's disease progression: Insights from mendelian randomization, multi-omics integration, machine learning, and SHAP methodology. Computational biology and chemistry, 2026
  3. Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer. Frontiers in immunology, 2023
Available

Metadata Quality Components

Persisted metadata quality

100 pts
Clarity
100%
Weight
100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review
97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

  • Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
  • Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Tumor vs normal
Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
  • Disease context Crohn's disease, inflammatory bowel disease, ulcerative colitis Disease context came from Normalization rules.
  • Likely case group Ulcerative colitis 74 samples
  • Likely control group Control 25 samples

Intent Interpretation

  • Downgrade or exclusion reason Downgraded assay: microarray cohorts are separated from the RNA-seq intent. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Comparison: Disease/model vs control. Specimen: Tissue. Comparison suitability: 0%.
  • Interpreted disease metadata: Crohn's disease, Inflammatory bowel disease, Ulcerative colitis.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 5 publications; 5 DOIs available: PMID 22606341, PMID 22719822, PMID 25182475, PMID 36742294, PMID 42269260.
  • Publication context: An ileal Crohn's disease gene signature based on whole human genome expression profiles of disease unaffected ileal mucosal biopsies.. PloS one, 2012. PMID 22606341. DOI 10.1371/journal.pone.0037139.
  • Publication context: Host genes related to paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition.. PloS one, 2012. PMID 22719822. DOI 10.1371/journal.pone.0030044.
  • Publication context: Identifying candidate genes for discrimination of ulcerative colitis and Crohn's disease.. Molecular biology reports, 2014. PMID 25182475. DOI 10.1007/s11033-014-3469-y.
  • Publication context: 2 additional linked PubMed publications are available.

Cautions

  • Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
  • Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Normalized Fields

303 fields

Sample Group Preview

showing 75 of 99 preview rows Show Hide
Study totals: Case 74 | Control 25 | Unassigned 0 | Excluded 0 | Ambiguous 0 showing 75 of 99 preview rows
Group Role Accession Title Source / characteristics Reason
Ulcerative colitis Case GSM597230 UC7 T110-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597231 UC59 T56-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597232 UC89 T74-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597233 UC153 T119-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597234 UC167 T227-S-Ni vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597235 UC177 T221-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597236 UC221 T221-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597237 UC256 T245-S-II vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597238 UC297 T272-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597239 UC309 T284-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597240 UC384 T452-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597241 UC385 T453-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597242 UC175 T325-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597243 UC335 T329-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597244 UC348 T345-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597245 UC379 T442-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597246 UC199 T222-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597247 UC238 T297-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597248 UC201 T285-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597249 UC107 T294-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597250 UC306 T288-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597251 UC386 T455-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597252 UC380 T459-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597253 UC394 T465-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597254 UC396 T478-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597255 UC165 T150-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Ulcerative colitis Case GSM597256 UC250 T238-S-II vs. N-17 T26-S-NI Disease-unaffected ileum from ulcerative colitis patient Tissue: Proximal ileal margin; Disease phenotype: Ulcerative colitis Case marker detected.
Crohn's disease Case GSM597257 CD-15 14881 NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597258 CD-19 14892 NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597259 CD-22 14892 NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597260 CD-235 T58-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597261 CD-256 T67-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597262 CD-312 T78-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597263 CD-275 T70-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597264 CD-185 T9-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597265 CD-493 T142-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597266 CD-340 T108-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597267 CD-401 T97-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597268 CD-133 T5-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597269 CD-233 T95-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597270 CD-382 T93-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597271 CD-196 T27-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597272 CD-155 T37-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597273 CD-124 T1-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597274 CD-178 T4-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597275 CD-323 T176-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597276 CD-563 T191-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597277 CD-557 T194-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597278 CD-216 T91-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
Crohn's disease Case GSM597279 CD-404 T100-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from Crohn's disease patient Tissue: Proximal ileal margin; Disease phenotype: Illeal Crohn's disease Case marker detected.
24 additional case samples are hidden from this preview.
Control Control GSM597304 N-13 T14-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597305 N-19 T30-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597306 N-34 T217-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597307 N-15 T23-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597308 N-33 T213-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597309 N-46 T216-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597310 N-49 T267-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597311 N-52 T271-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597312 N-55 T277-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597313 N-38 T240-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597314 N-39 T244-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597315 N-41 T246-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597316 N-42 T249-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597317 N-54 T274-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597318 N-75 T312-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597319 N-93 T349-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597320 N-98 T356-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597321 N-35 T224-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597322 N-37 T236-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597323 N-48 T266-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597324 N-50 T269-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597325 N-53 T273-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597326 N-69 T304-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597327 N-133 T414-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.
Control Control GSM597328 N-73 T310-S-NI vs. N-17 T26-S-NI Disease-unaffected ileum from control Tissue: Proximal ileal margin; Disease phenotype: No inflammatory bowel disease Sample-local control marker detected.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.