Matching samples

GSE25220 · Transcription levels in human colon biopsies in IBS and IBD patients before and after participating in a high red-meat dietary intervention

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

25 case / 0 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (44)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

GSM620750

Uncertain

Subject2_before

Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Insufficient evidence
        • The required value is not reported.
        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
          • Supported by the indexed evidence.
          • specimen category excludes: Biofluid — Meets requirement
            • Supported by the indexed evidence.
            Source metadata
            Source name
            Human colon biopsies before intervention
            Characteristics
            subject number: Subject2; disease status: IBD; gender: male; age: 57; intervention status: before
            Description
            Not reported
            Indexed organism evidence
            INFERRED · PARENT_INHERITED: Not reported
            Indexed assay evidence
            INFERRED · PARENT_INHERITED: Not reported
            Source
            GEO
            Original indexed metadata
            sample_accession: GSM620750
            sample_title: Subject2_before
            source_name: Human colon biopsies before intervention
            characteristics: subject number: Subject2; disease status: IBD; gender: male; age: 57; intervention status: before

            GSM620751

            Uncertain

            Subject2_after

            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

            Requirements and decision evidence
            • organism: Homo sapiens — Insufficient evidence
              • The required value is not reported.
              • assay type: bulk RNA-seq — Insufficient evidence
                • The required value is not reported.
                • specimen category: Tissue or biopsy — Insufficient evidence
                  • The required value is not reported.
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Meets requirement
                      • Supported by the indexed evidence.
                      Source metadata
                      Source name
                      Human colon biopsies after intervention
                      Characteristics
                      subject number: Subject2; disease status: IBD; gender: male; age: 57; intervention status: after
                      Description
                      Not reported
                      Indexed organism evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Indexed assay evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Source
                      GEO
                      Original indexed metadata
                      sample_accession: GSM620751
                      sample_title: Subject2_after
                      source_name: Human colon biopsies after intervention
                      characteristics: subject number: Subject2; disease status: IBD; gender: male; age: 57; intervention status: after

                      GSM620752

                      Uncertain

                      Subject3_before

                      Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                      Requirements and decision evidence
                      • Case: organism: Homo sapiens — Insufficient evidence
                        • The required value is not reported.
                        • Case: assay type: bulk RNA-seq — Insufficient evidence
                          • The required value is not reported.
                          • Case: specimen category: Tissue or biopsy — Insufficient evidence
                            • The required value is not reported.
                            • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                              • Supported by the indexed evidence.
                              • Case: specimen category excludes: Biofluid — Meets requirement
                                • Supported by the indexed evidence.
                                • Control: organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • Control: assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                      • The required value is not reported.
                                      • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                        • Supported by the indexed evidence.
                                        • Control: specimen category excludes: Biofluid — Meets requirement
                                          • Supported by the indexed evidence.
                                          Source metadata
                                          Source name
                                          Human colon biopsies before intervention
                                          Characteristics
                                          subject number: Subject3; disease status: IBS; gender: female; age: 65; intervention status: before
                                          Description
                                          Not reported
                                          Indexed organism evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Indexed assay evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Source
                                          GEO
                                          Original indexed metadata
                                          sample_accession: GSM620752
                                          sample_title: Subject3_before
                                          source_name: Human colon biopsies before intervention
                                          characteristics: subject number: Subject3; disease status: IBS; gender: female; age: 65; intervention status: before

                                          GSM620753

                                          Uncertain

                                          Subject3_after

                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                          Requirements and decision evidence
                                          • Case: organism: Homo sapiens — Insufficient evidence
                                            • The required value is not reported.
                                            • Case: assay type: bulk RNA-seq — Insufficient evidence
                                              • The required value is not reported.
                                              • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                • The required value is not reported.
                                                • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • Case: specimen category excludes: Biofluid — Meets requirement
                                                    • Supported by the indexed evidence.
                                                    • Control: organism: Homo sapiens — Insufficient evidence
                                                      • The required value is not reported.
                                                      • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                        • The required value is not reported.
                                                        • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                          • The required value is not reported.
                                                          • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                            • Supported by the indexed evidence.
                                                            • Control: specimen category excludes: Biofluid — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              Source metadata
                                                              Source name
                                                              Human colon biopsies after intervention
                                                              Characteristics
                                                              subject number: Subject3; disease status: IBS; gender: female; age: 65; intervention status: after
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM620753
                                                              sample_title: Subject3_after
                                                              source_name: Human colon biopsies after intervention
                                                              characteristics: subject number: Subject3; disease status: IBS; gender: female; age: 65; intervention status: after

                                                              GSM620754

                                                              Uncertain

                                                              Subject4_before

                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                              Requirements and decision evidence
                                                              • Case: organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                    • The required value is not reported.
                                                                    • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                      • Supported by the indexed evidence.
                                                                      • Case: specimen category excludes: Biofluid — Meets requirement
                                                                        • Supported by the indexed evidence.
                                                                        • Control: organism: Homo sapiens — Insufficient evidence
                                                                          • The required value is not reported.
                                                                          • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                  • Supported by the indexed evidence.
                                                                                  Source metadata
                                                                                  Source name
                                                                                  Human colon biopsies before intervention
                                                                                  Characteristics
                                                                                  subject number: Subject4; disease status: IBS; gender: male; age: 44; intervention status: before
                                                                                  Description
                                                                                  Not reported
                                                                                  Indexed organism evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Indexed assay evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Source
                                                                                  GEO
                                                                                  Original indexed metadata
                                                                                  sample_accession: GSM620754
                                                                                  sample_title: Subject4_before
                                                                                  source_name: Human colon biopsies before intervention
                                                                                  characteristics: subject number: Subject4; disease status: IBS; gender: male; age: 44; intervention status: before

                                                                                  GSM620755

                                                                                  Uncertain

                                                                                  Subject5_before

                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                  Requirements and decision evidence
                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                      • The required value is not reported.
                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                          • Supported by the indexed evidence.
                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            Source metadata
                                                                                            Source name
                                                                                            Human colon biopsies before intervention
                                                                                            Characteristics
                                                                                            subject number: Subject5; disease status: IBD; gender: male; age: 72; intervention status: before
                                                                                            Description
                                                                                            Not reported
                                                                                            Indexed organism evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Indexed assay evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Source
                                                                                            GEO
                                                                                            Original indexed metadata
                                                                                            sample_accession: GSM620755
                                                                                            sample_title: Subject5_before
                                                                                            source_name: Human colon biopsies before intervention
                                                                                            characteristics: subject number: Subject5; disease status: IBD; gender: male; age: 72; intervention status: before

                                                                                            GSM620756

                                                                                            Uncertain

                                                                                            Subject6_before

                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                            Requirements and decision evidence
                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                  • The required value is not reported.
                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                    • Supported by the indexed evidence.
                                                                                                    • specimen category excludes: Biofluid — Meets requirement
                                                                                                      • Supported by the indexed evidence.
                                                                                                      Source metadata
                                                                                                      Source name
                                                                                                      Human colon biopsies before intervention
                                                                                                      Characteristics
                                                                                                      subject number: Subject6; disease status: IBD; gender: male; age: 60; intervention status: before
                                                                                                      Description
                                                                                                      Not reported
                                                                                                      Indexed organism evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Indexed assay evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Source
                                                                                                      GEO
                                                                                                      Original indexed metadata
                                                                                                      sample_accession: GSM620756
                                                                                                      sample_title: Subject6_before
                                                                                                      source_name: Human colon biopsies before intervention
                                                                                                      characteristics: subject number: Subject6; disease status: IBD; gender: male; age: 60; intervention status: before

                                                                                                      GSM620757

                                                                                                      Uncertain

                                                                                                      Subject6_after

                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                      Requirements and decision evidence
                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                        • The required value is not reported.
                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • specimen category excludes: Biofluid — Meets requirement
                                                                                                                • Supported by the indexed evidence.
                                                                                                                Source metadata
                                                                                                                Source name
                                                                                                                Human colon biopsies after intervention
                                                                                                                Characteristics
                                                                                                                subject number: Subject6; disease status: IBD; gender: male; age: 60; intervention status: after
                                                                                                                Description
                                                                                                                Not reported
                                                                                                                Indexed organism evidence
                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                Indexed assay evidence
                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                Source
                                                                                                                GEO
                                                                                                                Original indexed metadata
                                                                                                                sample_accession: GSM620757
                                                                                                                sample_title: Subject6_after
                                                                                                                source_name: Human colon biopsies after intervention
                                                                                                                characteristics: subject number: Subject6; disease status: IBD; gender: male; age: 60; intervention status: after

                                                                                                                GSM620758

                                                                                                                Uncertain

                                                                                                                Subject7_before

                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                Requirements and decision evidence
                                                                                                                • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                    • The required value is not reported.
                                                                                                                    • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                        • Supported by the indexed evidence.
                                                                                                                        • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                • The required value is not reported.
                                                                                                                                • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                  • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                    Source metadata
                                                                                                                                    Source name
                                                                                                                                    Human colon biopsies before intervention
                                                                                                                                    Characteristics
                                                                                                                                    subject number: Subject7; disease status: IBS; gender: male; age: 57; intervention status: before
                                                                                                                                    Description
                                                                                                                                    Not reported
                                                                                                                                    Indexed organism evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Indexed assay evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Source
                                                                                                                                    GEO
                                                                                                                                    Original indexed metadata
                                                                                                                                    sample_accession: GSM620758
                                                                                                                                    sample_title: Subject7_before
                                                                                                                                    source_name: Human colon biopsies before intervention
                                                                                                                                    characteristics: subject number: Subject7; disease status: IBS; gender: male; age: 57; intervention status: before

                                                                                                                                    GSM620759

                                                                                                                                    Uncertain

                                                                                                                                    Subject7_after

                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                    Requirements and decision evidence
                                                                                                                                    • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                      • The required value is not reported.
                                                                                                                                      • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                              • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                  • The required value is not reported.
                                                                                                                                                  • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                      • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                        Source metadata
                                                                                                                                                        Source name
                                                                                                                                                        Human colon biopsies after intervention
                                                                                                                                                        Characteristics
                                                                                                                                                        subject number: Subject7; disease status: IBS; gender: male; age: 57; intervention status: after
                                                                                                                                                        Description
                                                                                                                                                        Not reported
                                                                                                                                                        Indexed organism evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Indexed assay evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Source
                                                                                                                                                        GEO
                                                                                                                                                        Original indexed metadata
                                                                                                                                                        sample_accession: GSM620759
                                                                                                                                                        sample_title: Subject7_after
                                                                                                                                                        source_name: Human colon biopsies after intervention
                                                                                                                                                        characteristics: subject number: Subject7; disease status: IBS; gender: male; age: 57; intervention status: after

                                                                                                                                                        GSM620760

                                                                                                                                                        Uncertain

                                                                                                                                                        Subject8_before

                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                        • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                              • The required value is not reported.
                                                                                                                                                              • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                  • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                    • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                          • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                            Source metadata
                                                                                                                                                                            Source name
                                                                                                                                                                            Human colon biopsies before intervention
                                                                                                                                                                            Characteristics
                                                                                                                                                                            subject number: Subject8; disease status: IBS; gender: female; age: 25; intervention status: before
                                                                                                                                                                            Description
                                                                                                                                                                            Not reported
                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Source
                                                                                                                                                                            GEO
                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                            sample_accession: GSM620760
                                                                                                                                                                            sample_title: Subject8_before
                                                                                                                                                                            source_name: Human colon biopsies before intervention
                                                                                                                                                                            characteristics: subject number: Subject8; disease status: IBS; gender: female; age: 25; intervention status: before

                                                                                                                                                                            GSM620761

                                                                                                                                                                            Uncertain

                                                                                                                                                                            Subject8_after

                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                            • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                    • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                      • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                            • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                              • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                Source name
                                                                                                                                                                                                Human colon biopsies after intervention
                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                subject number: Subject8; disease status: IBS; gender: female; age: 25; intervention status: after
                                                                                                                                                                                                Description
                                                                                                                                                                                                Not reported
                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                Source
                                                                                                                                                                                                GEO
                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                sample_accession: GSM620761
                                                                                                                                                                                                sample_title: Subject8_after
                                                                                                                                                                                                source_name: Human colon biopsies after intervention
                                                                                                                                                                                                characteristics: subject number: Subject8; disease status: IBS; gender: female; age: 25; intervention status: after

                                                                                                                                                                                                GSM620762

                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                Subject9_before

                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                        • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                          Source name
                                                                                                                                                                                                          Human colon biopsies before intervention
                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                          subject number: Subject9; disease status: IBD; gender: male; age: 31; intervention status: before
                                                                                                                                                                                                          Description
                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Source
                                                                                                                                                                                                          GEO
                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                          sample_accession: GSM620762
                                                                                                                                                                                                          sample_title: Subject9_before
                                                                                                                                                                                                          source_name: Human colon biopsies before intervention
                                                                                                                                                                                                          characteristics: subject number: Subject9; disease status: IBD; gender: male; age: 31; intervention status: before

                                                                                                                                                                                                          GSM620763

                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                          Subject9_after

                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                    Human colon biopsies after intervention
                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                    subject number: Subject9; disease status: IBD; gender: male; age: 31; intervention status: after
                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                    sample_accession: GSM620763
                                                                                                                                                                                                                    sample_title: Subject9_after
                                                                                                                                                                                                                    source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                    characteristics: subject number: Subject9; disease status: IBD; gender: male; age: 31; intervention status: after

                                                                                                                                                                                                                    GSM620764

                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                    Subject10_before

                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                              subject number: Subject10; disease status: IBD; gender: female; age: 48; intervention status: before
                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                              sample_accession: GSM620764
                                                                                                                                                                                                                              sample_title: Subject10_before
                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                              characteristics: subject number: Subject10; disease status: IBD; gender: female; age: 48; intervention status: before

                                                                                                                                                                                                                              GSM620765

                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                              Subject10_after

                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                        Human colon biopsies after intervention
                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                        subject number: Subject10; disease status: IBD; gender: female; age: 48; intervention status: after
                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                        sample_accession: GSM620765
                                                                                                                                                                                                                                        sample_title: Subject10_after
                                                                                                                                                                                                                                        source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                        characteristics: subject number: Subject10; disease status: IBD; gender: female; age: 48; intervention status: after

                                                                                                                                                                                                                                        GSM620766

                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                        Subject11_before

                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                  Human colon biopsies before intervention
                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                  subject number: Subject11; disease status: IBD; gender: male; age: 54; intervention status: before
                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                  sample_accession: GSM620766
                                                                                                                                                                                                                                                  sample_title: Subject11_before
                                                                                                                                                                                                                                                  source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                  characteristics: subject number: Subject11; disease status: IBD; gender: male; age: 54; intervention status: before

                                                                                                                                                                                                                                                  GSM620767

                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                  Subject12_before

                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                            Human colon biopsies before intervention
                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                            subject number: Subject12; disease status: IBD; gender: male; age: 71; intervention status: before
                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                            sample_accession: GSM620767
                                                                                                                                                                                                                                                            sample_title: Subject12_before
                                                                                                                                                                                                                                                            source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                            characteristics: subject number: Subject12; disease status: IBD; gender: male; age: 71; intervention status: before

                                                                                                                                                                                                                                                            GSM620768

                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                            Subject12_after

                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                      Human colon biopsies after intervention
                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                      subject number: Subject12; disease status: IBD; gender: male; age: 71; intervention status: after
                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                      sample_accession: GSM620768
                                                                                                                                                                                                                                                                      sample_title: Subject12_after
                                                                                                                                                                                                                                                                      source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                                                      characteristics: subject number: Subject12; disease status: IBD; gender: male; age: 71; intervention status: after

                                                                                                                                                                                                                                                                      GSM620769

                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                      Subject14_before

                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                      • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                        • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                          • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                              • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                    • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                      • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                        • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                          Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                          subject number: Subject14; disease status: IBS; gender: female; age: 63; intervention status: before
                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                          sample_accession: GSM620769
                                                                                                                                                                                                                                                                                          sample_title: Subject14_before
                                                                                                                                                                                                                                                                                          source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                          characteristics: subject number: Subject14; disease status: IBS; gender: female; age: 63; intervention status: before

                                                                                                                                                                                                                                                                                          GSM620770

                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                          Subject15_before

                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                    Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                    subject number: Subject15; disease status: IBD; gender: male; age: 29; intervention status: before
                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                    sample_accession: GSM620770
                                                                                                                                                                                                                                                                                                    sample_title: Subject15_before
                                                                                                                                                                                                                                                                                                    source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                    characteristics: subject number: Subject15; disease status: IBD; gender: male; age: 29; intervention status: before

                                                                                                                                                                                                                                                                                                    GSM620771

                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                    Subject16_before

                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                              subject number: Subject16; disease status: IBD; gender: male; age: 29; intervention status: before
                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                              sample_accession: GSM620771
                                                                                                                                                                                                                                                                                                              sample_title: Subject16_before
                                                                                                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                              characteristics: subject number: Subject16; disease status: IBD; gender: male; age: 29; intervention status: before

                                                                                                                                                                                                                                                                                                              GSM620772

                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                              Subject17_before

                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                              • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                  • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                    • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                      • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                        • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                          • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                            • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                              • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                  Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                  subject number: Subject17; disease status: IBS; gender: male; age: 61; intervention status: before
                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM620772
                                                                                                                                                                                                                                                                                                                                  sample_title: Subject17_before
                                                                                                                                                                                                                                                                                                                                  source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                  characteristics: subject number: Subject17; disease status: IBS; gender: male; age: 61; intervention status: before

                                                                                                                                                                                                                                                                                                                                  GSM620773

                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                  Subject17_after

                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                  • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                    • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                      • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                        • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                          • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                            • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                              • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                  • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                    • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                      Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                      subject number: Subject17; disease status: IBS; gender: male; age: 61; intervention status: after
                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM620773
                                                                                                                                                                                                                                                                                                                                                      sample_title: Subject17_after
                                                                                                                                                                                                                                                                                                                                                      source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                      characteristics: subject number: Subject17; disease status: IBS; gender: male; age: 61; intervention status: after

                                                                                                                                                                                                                                                                                                                                                      GSM620774

                                                                                                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                                                                                                      Subject18_before

                                                                                                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                      • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                        • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                          • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                            • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                              • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                  • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                    • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                      • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                        • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                          Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                          subject number: Subject18; disease status: IBS; gender: female; age: 39; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM620774
                                                                                                                                                                                                                                                                                                                                                                          sample_title: Subject18_before
                                                                                                                                                                                                                                                                                                                                                                          source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject number: Subject18; disease status: IBS; gender: female; age: 39; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                          GSM620775

                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                          Subject19_before

                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                          • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                            • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                              • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                  • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                    • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                      • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                        • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                          • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                            • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                              subject number: Subject19; disease status: IBS; gender: male; age: 65; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM620775
                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Subject19_before
                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject number: Subject19; disease status: IBS; gender: male; age: 65; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                              GSM620776

                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                              Subject20_before

                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                        Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                        subject number: Subject20; disease status: IBD; gender: female; age: 55; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM620776
                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Subject20_before
                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject number: Subject20; disease status: IBD; gender: female; age: 55; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                        GSM620777

                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                        Subject21_before

                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                        • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                          • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                            • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                              • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                  • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                    • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                      • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                        • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                            Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                            subject number: Subject21; disease status: IBS; gender: male; age: 69; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM620777
                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Subject21_before
                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject number: Subject21; disease status: IBS; gender: male; age: 69; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                            GSM620778

                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                            Subject22_before

                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                              • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                    • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                subject number: Subject22; disease status: IBS; gender: female; age: 65; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM620778
                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Subject22_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject number: Subject22; disease status: IBS; gender: female; age: 65; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM620779

                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                Subject23_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                          subject number: Subject23; disease status: IBD; gender: male; age: 53; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM620779
                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_title: Subject23_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                          source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject number: Subject23; disease status: IBD; gender: male; age: 53; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM620780

                                                                                                                                                                                                                                                                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                          Subject24_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject number: Subject24; disease status: IBD; gender: female; age: 40; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM620780
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Subject24_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject number: Subject24; disease status: IBD; gender: female; age: 40; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM620781

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Subject25_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject number: Subject25; disease status: IBD; gender: male; age: 51; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM620781
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Subject25_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject number: Subject25; disease status: IBD; gender: male; age: 51; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM620782

                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Subject26_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject number: Subject26; disease status: IBD; gender: female; age: 54; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM620782
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Subject26_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject number: Subject26; disease status: IBD; gender: female; age: 54; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM620783

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Subject27_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  subject number: Subject27; disease status: IBD; gender: male; age: 40; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM620783
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Subject27_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject number: Subject27; disease status: IBD; gender: male; age: 40; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM620784

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Subject27_after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            subject number: Subject27; disease status: IBD; gender: male; age: 40; intervention status: after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM620784
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Subject27_after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject number: Subject27; disease status: IBD; gender: male; age: 40; intervention status: after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM620785

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Subject28_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                subject number: Subject28; disease status: IBS; gender: male; age: 64; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM620785
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Subject28_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject number: Subject28; disease status: IBS; gender: male; age: 64; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM620786

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Subject28_after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject number: Subject28; disease status: IBS; gender: male; age: 64; intervention status: after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM620786
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Subject28_after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject number: Subject28; disease status: IBS; gender: male; age: 64; intervention status: after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM620787

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Subject29_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject number: Subject29; disease status: IBD; gender: male; age: 47; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM620787
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Subject29_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject number: Subject29; disease status: IBD; gender: male; age: 47; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM620788

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Subject30_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject number: Subject30; disease status: IBD; gender: male; age: 54; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM620788
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Subject30_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject number: Subject30; disease status: IBD; gender: male; age: 54; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM620789

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Subject31_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            subject number: Subject31; disease status: IBS; gender: female; age: 58; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM620789
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Subject31_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject number: Subject31; disease status: IBS; gender: female; age: 58; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM620790

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Subject31_after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                subject number: Subject31; disease status: IBS; gender: female; age: 58; intervention status: after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM620790
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Subject31_after
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human colon biopsies after intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject number: Subject31; disease status: IBS; gender: female; age: 58; intervention status: after

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM620791

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Subject32_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject number: Subject32; disease status: IBS; gender: male; age: 46; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM620791
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Subject32_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject number: Subject32; disease status: IBS; gender: male; age: 46; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM620792

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Subject33_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject number: Subject33; disease status: IBD; gender: male; age: 46; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM620792
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Subject33_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject number: Subject33; disease status: IBD; gender: male; age: 46; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM620793

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Subject56_before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject number: Subject56; disease status: IBD; gender: male; age: 55; intervention status: before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM620793
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Subject56_before
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human colon biopsies before intervention
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject number: Subject56; disease status: IBD; gender: male; age: 55; intervention status: before

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded samples (0)

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        No excluded samples.