GSE276395

Gene expression dysregulation in whole blood of patients with C. difficile infection

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source
GEO
Assay
microarray
Organism
Homo sapiens
Whole-study samples
278 samples
Specimen
Biofluid
Reported/interpreted study design
Unclear study design Design classification does not establish patient pairs.
Comparison type
Tumor vs normal
Contributors
Tsakiroglou M, Evans A, Carracedo AD, Little M, Hornby R, Roberts P, Zhang E, Miyajima F, Pirmohamed M
Contact name
Maria Tsakiroglou
Submission date
2024-09-05
Last update
2025-01-02
Organization
University of Liverpool
Department
Department of Pharmacology and Therapeutics
Public date
2024-11-24
Experiment types
Expression profiling by array
Platforms
GPL23126 [Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version]
Series type
Series
SubSeries
Not available
BioProject
PRJNA1157210

Summary

Background: Clostridioides difficile (C. difficile) is a global threat and has significant implications for individuals and health care systems. Little is known about host molecular mechanisms and transcriptional changes in peripheral immune cells. This is the first gene expression study in whole blood of patients with C. difficile infection. Methods: We took blood and stool samples from patients with toxigenic C. difficile infection (CDI), non-toxigenic C. difficile infection (GDH), inflammatory bowel disease (IBD), diarrhoea from other causes (DC) and healthy controls (HC). We performed transcriptome-wide RNA profiling on peripheral blood to identify diarrhoea common and CDI unique gene sets. Results: Diarrhoea groups upregulated innate immune responses with neutrophils at the epicentre. The common signature associated with diarrhoea was non-specific and shared by various other inflammatory conditions. CDI had a unique 45-gene set reflecting downregulation of humoral and T cell memory functions. Dysregulation of immunometabolic genes was also abundant and linked to immune cell fate during differentiation. Conclusions: Whole transcriptome analysis of white cells in blood from patients with toxigenic C. difficile infection showed that there is an impairment of adaptive immunity and immunometabolism.

Overall design

278 whole blood samples were assayed, with some participants in the CDI group also measured ~2 weeks post-baseline. In total there are 78 samples from the CDI group at baseline, plus 27 at the 2-week time point; 45 samples from the diarrhoea from other causes (DC) group; 37 samples from the non-toxigenic C. difficile infection (GDH) group; 40 from the inflammatory bowel disease (IBD) group and 51 from the healthy control (HC) group.

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
278 GSM samples
 Primary source
recount3

Planned trusted source for processed count availability.

 No match found
Expression Atlas

Planned source for curated expression experiment links.

 No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

2 linked publications 2 DOIs

Primary publication

  1. Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection. International journal of molecular sciences, 2024

Related publications

  1. Blood transcriptomics identifies FEZ1 as a potential biomarker for inflammatory bowel disease. Computers in biology and medicine, 2025
Available

Metadata Quality Components

Persisted metadata quality

93 pts
Clarity
93%
Weight
100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Only one side of the comparison is clearly grouped. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Not ready
43% DE readiness

Contrast completeness

10/25 pts

Only one side of the contrast is present; downstream DE needs both groups.

Minimum group size

0/20 pts

Minimum group size cannot be evaluated until a complete contrast exists.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

3/15 pts

Unassigned or review-needed samples remain before analysis.

Blocking warnings

0/10 pts

Critical warnings must be resolved before downstream analysis.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

  • No complete case/control contrast is available.
  • 238 samples are still unassigned.
  • Critical dataset warnings must be resolved.

Next Steps

  • Resolve unassigned or review-needed samples in the grouping table.
  • Resolve critical warnings before downstream analysis.

Analysis Preparation Checklist

3/6 ready

Group labels reviewed

Blocked

No complete case/control grouping exists yet.

Review the sample grouping table and assign both case and control groups.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Needs review

0 review-needed samples and 238 unassigned samples remain.

Resolve ambiguous and unassigned samples before finalizing the contrast.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Analysis readiness has blockers that must be resolved before DE.

Analysis preparation checklist contains blocked items.

No complete case/control or treatment/control contrast is available.

At least one comparison group has fewer than two samples.

One or more samples are unassigned and need manual grouping decisions.

Critical dataset warnings are present.

Assay context may require expert handling before DESeq2-style analysis.

Study design is model-system or unclear and should be reviewed before analysis.

Why This Is Ranked Here

Tumor vs normal
Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
  • Disease context Inflammatory bowel disease Disease context came from Normalization rules.
  • Likely case group Inflammatory bowel disease 40 samples
  • Likely control group No control group detected 0 samples

Intent Interpretation

  • Downgrade or exclusion reason Comparison: Unclear study design. Specimen: Biofluid. Comparison suitability: 0%. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Interpreted disease metadata: Infectious disease or host response, Inflammatory bowel disease.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 2 publications; 2 DOIs available: PMID 39684365, PMID 39894009.
  • Publication context: Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection.. International journal of molecular sciences, 2024. PMID 39684365. DOI 10.3390/ijms252312653.
  • Publication context: Blood transcriptomics identifies FEZ1 as a potential biomarker for inflammatory bowel disease.. Computers in biology and medicine, 2025. PMID 39894009. DOI 10.1016/j.compbiomed.2025.109742.

Cautions

  • Comparison: Unclear study design. Specimen: Biofluid. Comparison suitability: 0%.
  • Downgraded for tissue search because it is a biofluid cohort.
  • Downgraded for tissue search because study design or specimen source is unclear.
  • Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
  • Blood, plasma, or serum cohort downgraded because this ranking targets tissue tumor-vs-normal comparisons.
  • Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
  • Missing or unclear metadata. Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Missing or unclear metadata. Comparison - Unclear study design. Specimen - Biofluid. Comparison suitability: 0%.
  • Missing or unclear metadata. Downgraded for tissue search because study design or specimen source is unclear.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Normalized Fields

showing 500 of 878 fields

Sample Group Preview

showing 90 of 278 preview rows Show Hide
Study totals: Case 40 | Control 0 | Unassigned 238 | Excluded 0 | Ambiguous 0 showing 90 of 278 preview rows
Group Role Accession Title Source / characteristics Reason
Inflammatory bowel disease Case GSM8497807 Blood-CDB_756696_0wk Whole blood Participant_id: CDB_756696; Condition: IBD; Age: 69; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497808 Blood-CDB_232906_0wk Whole blood Participant_id: CDB_232906; Condition: IBD; Age: 48; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497809 Blood-CDB_261850_0wk Whole blood Participant_id: CDB_261850; Condition: IBD; Age: 26; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497810 Blood-CDB_461815_0wk Whole blood Participant_id: CDB_461815; Condition: IBD; Age: 20; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497811 Blood-CDB_651333_0wk Whole blood Participant_id: CDB_651333; Condition: IBD; Age: 38; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497813 Blood-CDB_822500_0wk Whole blood Participant_id: CDB_822500; Condition: IBD; Age: 25; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497814 Blood-CDB_312111_0wk Whole blood Participant_id: CDB_312111; Condition: IBD; Age: 67; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497815 Blood-CDB_656930_0wk Whole blood Participant_id: CDB_656930; Condition: IBD; Age: 22; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497816 Blood-CDB_238581_0wk Whole blood Participant_id: CDB_238581; Condition: IBD; Age: 51; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497817 Blood-CDB_994153_0wk Whole blood Participant_id: CDB_994153; Condition: IBD; Age: 73; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497818 Blood-CDB_449897_0wk Whole blood Participant_id: CDB_449897; Condition: IBD; Age: 64; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497819 Blood-CDB_447571_0wk Whole blood Participant_id: CDB_447571; Condition: IBD; Age: 54; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497820 Blood-CDB_376429_0wk Whole blood Participant_id: CDB_376429; Condition: IBD; Age: 67; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497821 Blood-CDB_808513_0wk Whole blood Participant_id: CDB_808513; Condition: IBD; Age: 21; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497822 Blood-CDB_649482_0wk Whole blood Participant_id: CDB_649482; Condition: IBD; Age: 70; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497824 Blood-CDB_873553_0wk Whole blood Participant_id: CDB_873553; Condition: IBD; Age: 70; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497825 Blood-CDB_104369_0wk Whole blood Participant_id: CDB_104369; Condition: IBD; Age: 31; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497826 Blood-CDB_720223_0wk Whole blood Participant_id: CDB_720223; Condition: IBD; Age: 41; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497827 Blood-CDB_731372_0wk Whole blood Participant_id: CDB_731372; Condition: IBD; Age: 44; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497828 Blood-CDB_813365_0wk Whole blood Participant_id: CDB_813365; Condition: IBD; Age: 67; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497829 Blood-CDB_404305_0wk Whole blood Participant_id: CDB_404305; Condition: IBD; Age: 81; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497830 Blood-CDB_577305_0wk Whole blood Participant_id: CDB_577305; Condition: IBD; Age: 29; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497831 Blood-CDB_796339_0wk Whole blood Participant_id: CDB_796339; Condition: IBD; Age: 20; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497832 Blood-CDB_265166_0wk Whole blood Participant_id: CDB_265166; Condition: IBD; Age: 63; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497833 Blood-CDB_423244_0wk Whole blood Participant_id: CDB_423244; Condition: IBD; Age: 31; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497835 Blood-CDB_305527_0wk Whole blood Participant_id: CDB_305527; Condition: IBD; Age: 18; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497836 Blood-CDB_411020_0wk Whole blood Participant_id: CDB_411020; Condition: IBD; Age: 21; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497837 Blood-CDB_858243_0wk Whole blood Participant_id: CDB_858243; Condition: IBD; Age: 60; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497838 Blood-CDB_904729_0wk Whole blood Participant_id: CDB_904729; Condition: IBD; Age: 33; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497839 Blood-CDB_727847_0wk Whole blood Participant_id: CDB_727847; Condition: IBD; Age: 31; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497840 Blood-CDB_831693_0wk Whole blood Participant_id: CDB_831693; Condition: IBD; Age: 34; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497841 Blood-CDB_187373_0wk Whole blood Participant_id: CDB_187373; Condition: IBD; Age: 27; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497842 Blood-CDB_893435_0wk Whole blood Participant_id: CDB_893435; Condition: IBD; Age: 50; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497926 Blood-CDB_611256_0wk Whole blood Participant_id: CDB_611256; Condition: IBD; Age: 32; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497927 Blood-CDB_815858_0wk Whole blood Participant_id: CDB_815858; Condition: IBD; Age: 67; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497928 Blood-CDB_947332_0wk Whole blood Participant_id: CDB_947332; Condition: IBD; Age: 59; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497929 Blood-CDB_602306_0wk Whole blood Participant_id: CDB_602306; Condition: IBD; Age: 22; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497930 Blood-CDB_492390_0wk Whole blood Participant_id: CDB_492390; Condition: IBD; Age: 36; Sex: Female; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497931 Blood-CDB_553481_0wk Whole blood Participant_id: CDB_553481; Condition: IBD; Age: 68; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Inflammatory bowel disease Case GSM8497932 Blood-CDB_866141_0wk Whole blood Participant_id: CDB_866141; Condition: IBD; Age: 38; Sex: Male; Time_point_sample_weeks: 0 Case marker detected.
Unassigned Unassigned GSM8497748 Blood-CDH_639364_0wk Whole blood Participant_id: CDH_639364; Condition: HC; Age: 49; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497749 Blood-CDH_888066_0wk Whole blood Participant_id: CDH_888066; Condition: HC; Age: 70; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497750 Blood-CDH_135248_0wk Whole blood Participant_id: CDH_135248; Condition: HC; Age: 67; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497751 Blood-CDH_117276_0wk Whole blood Participant_id: CDH_117276; Condition: HC; Age: 81; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497752 Blood-CDH_647386_0wk Whole blood Participant_id: CDH_647386; Condition: HC; Age: 64; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497753 Blood-CDH_446298_0wk Whole blood Participant_id: CDH_446298; Condition: HC; Age: 63; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497754 Blood-CDH_346908_0wk Whole blood Participant_id: CDH_346908; Condition: HC; Age: 65; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497755 Blood-CDH_249849_0wk Whole blood Participant_id: CDH_249849; Condition: HC; Age: 60; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497756 Blood-CDH_293965_0wk Whole blood Participant_id: CDH_293965; Condition: HC; Age: 68; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497757 Blood-CDH_503294_0wk Whole blood Participant_id: CDH_503294; Condition: HC; Age: 63; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497758 Blood-CDU_696889_0wk Whole blood Participant_id: CDU_696889; Condition: DC; Age: 68; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497759 Blood-CDU_415483_0wk Whole blood Participant_id: CDU_415483; Condition: DC; Age: 80; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497760 Blood-CDU_731031_0wk Whole blood Participant_id: CDU_731031; Condition: DC; Age: 75; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497761 Blood-CDU_845124_0wk Whole blood Participant_id: CDU_845124; Condition: DC; Age: 81; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497762 Blood-CDU_587393_0wk Whole blood Participant_id: CDU_587393; Condition: DC; Age: 25; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497763 Blood-CDI_556083_0wk Whole blood Participant_id: CDI_556083; Condition: CDI; Age: 93; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497764 Blood-CDI_555629_0wk Whole blood Participant_id: CDI_555629; Condition: CDI; Age: 88; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497765 Blood-CDI_546501_0wk Whole blood Participant_id: CDI_546501; Condition: CDI; Age: 75; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497766 Blood-CDI_575655_0wk Whole blood Participant_id: CDI_575655; Condition: CDI; Age: 77; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497767 Blood-CDI_255870_0wk Whole blood Participant_id: CDI_255870; Condition: CDI; Age: 68; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497768 Blood-CDH_407690_0wk Whole blood Participant_id: CDH_407690; Condition: HC; Age: 69; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497769 Blood-CDI_788403_0wk Whole blood Participant_id: CDI_788403; Condition: CDI; Age: 67; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497770 Blood-CDI_799868_0wk Whole blood Participant_id: CDI_799868; Condition: CDI; Age: 67; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497771 Blood-CDI_250169_0wk Whole blood Participant_id: CDI_250169; Condition: CDI; Age: 56; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497772 Blood-CDI_255870_2wk Whole blood Participant_id: CDI_255870; Condition: CDI; Age: 68; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497773 Blood-CDI_540454_2wk Whole blood Participant_id: CDI_540454; Condition: CDI; Age: 66; Sex: Male; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497774 Blood-CDI_555613_2wk Whole blood Participant_id: CDI_555613; Condition: CDI; Age: 87; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497775 Blood-CDI_674850_2wk Whole blood Participant_id: CDI_674850; Condition: CDI; Age: 72; Sex: Male; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497776 Blood-CDI_450890_2wk Whole blood Participant_id: CDI_450890; Condition: CDI; Age: 79; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497777 Blood-CDI_738745_0wk Whole blood Participant_id: CDI_738745; Condition: CDI; Age: 83; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497778 Blood-CDI_841314_0wk Whole blood Participant_id: CDI_841314; Condition: CDI; Age: 75; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497779 Blood-CDH_101865_0wk Whole blood Participant_id: CDH_101865; Condition: HC; Age: 71; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497780 Blood-CDI_395042_0wk Whole blood Participant_id: CDI_395042; Condition: CDI; Age: 73; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497781 Blood-CDU_209712_0wk Whole blood Participant_id: CDU_209712; Condition: DC; Age: 60; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497782 Blood-CDU_134958_0wk Whole blood Participant_id: CDU_134958; Condition: DC; Age: 27; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497783 Blood-CDU_283137_0wk Whole blood Participant_id: CDU_283137; Condition: DC; Age: 81; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497784 Blood-CDU_960845_0wk Whole blood Participant_id: CDU_960845; Condition: DC; Age: 75; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497785 Blood-CDU_543472_0wk Whole blood Participant_id: CDU_543472; Condition: DC; Age: 69; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497786 Blood-CDU_434358_0wk Whole blood Participant_id: CDU_434358; Condition: DC; Age: 88; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497787 Blood-CDI_674850_0wk Whole blood Participant_id: CDI_674850; Condition: CDI; Age: 72; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497788 Blood-CDI_538843_0wk Whole blood Participant_id: CDI_538843; Condition: CDI; Age: 60; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497789 Blood-CDI_929162_2wk Whole blood Participant_id: CDI_929162; Condition: CDI; Age: 81; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497790 Blood-CDH_880992_0wk Whole blood Participant_id: CDH_880992; Condition: HC; Age: 50; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497791 Blood-CDI_265643_0wk Whole blood Participant_id: CDI_265643; Condition: CDI; Age: 75; Sex: Male; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497792 Blood-CDI_855533_2wk Whole blood Participant_id: CDI_855533; Condition: CDI; Age: 86; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497793 Blood-CDI_326720_0wk Whole blood Participant_id: CDI_326720; Condition: CDI; Age: 84; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497794 Blood-CDI_700705_2wk Whole blood Participant_id: CDI_700705; Condition: CDI; Age: 74; Sex: Male; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497795 Blood-CDI_558602_0wk Whole blood Participant_id: CDI_558602; Condition: CDI; Age: 88; Sex: Female; Time_point_sample_weeks: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM8497796 Blood-CDI_558602_2wk Whole blood Participant_id: CDI_558602; Condition: CDI; Age: 88; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM8497797 Blood-CDI_958056_2wk Whole blood Participant_id: CDI_958056; Condition: CDI; Age: 88; Sex: Female; Time_point_sample_weeks: 2 No explicit case or control marker detected.
188 additional unassigned samples are hidden from this preview.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.