Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

20 case / 10 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source: GEO
Assay: microarray
Organism: Homo sapiens
Whole-study samples: 30 samples
Specimen: Tissue
Reported/interpreted study design: Disease/model vs control Design classification does not establish patient pairs.

Comparison type: Tumor vs normal
Contributors: Woetzel D, Huber R, Kupfer P, Pohlers D, Pfaff M, Driesch D, Häupl T, Koczan D, Stiehl P, Guthke R, Kinne RW, Häupl T
Contact name: Thomas Häupl
Submission date: 2014-02-21
Last update: 2018-08-10
Organization: Charité
Department: Rheumatology
Public date: 2014-02-21
Experiment types: Expression profiling by array
Platforms: GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Series type: Series
SubSeries: Not available
BioProject: PRJNA238979

Summary

Discrimination of rheumatoid arthritis (RA) patients from patients with other inflammatory/degenerative joint diseases or healthy individuals purely on the basis of genes differentially expressed in high-throughput data has proven very difficult. Thus, the present study sought to achieve such discrimination by employing a novel unbiased approach using rule-based classifiers. Three multi-center genome-wide transcriptomic data sets (Affymetrix HG- U133 A/B) from a total of 79 individuals, including 20 healthy controls (control group - CG), as well as 26 osteoarthritis (OA) and 33 RA patients, were used to infer rule- based classifiers to discriminate the disease groups. The rules were ranked with respect to Kiendl’s statistical relevance index, and the resulting rule set was optimized by pruning. The rule sets were inferred separately from data of one of three centers and applied to the two remaining centers for validation. All rules from the optimized rule sets of all centers were used to analyze their biological relevance applying the software Pathway Studio. The optimized rule sets for the three centers contained a total of 29, 20, and 8 rules (including 10, 8, and 4 rules for ‘RA’), respectively. The mean sensitivity for the prediction of RA based on six center-to-center tests was 96% (range 90% to 100%), that for OA 86% (range 40% to 100%). The mean specificity for RA prediction was 94% (range 80% to 100%), that for OA 96% (range 83.3% to 100%). The average overall accuracy of the three different rule-based classifiers was 91% (range 80% to 100%). Unbiased analyses by Pathway Studio of the gene sets obtained by discrimination of RA from OA and CG with rule-based classifiers resulted in the identification of the pathogenetically and/or therapeutically relevant interferon-gamma and GM-CSF pathways. First-time application of rule-based classifiers for the discrimination of RA resulted in high performance, with means for all assessment parameters close to or higher than 90%. In addition, this unbiased, new approach resulted in the identification not only of pathways known to be critical to RA, but also of novel molecules such as serine/threonine kinase 10.

Overall design

Synovial tisssue from healthy joints, OA joints, and RA joints.

Source Evidence

4 sources

Source	Contribution	Status
GEO	Original dataset metadata, sample metadata, source links, and GEO data availability flags. Sample records 30 GSM samples	Primary source
recount3	Planned trusted source for processed count availability.	No match found
Expression Atlas	Curated expression experiment linkage and source URL. Expression Atlas accession E-GEOD-55235	Available
PubMed	Primary GEO citations and related PubMed articles that mention this dataset. 21 linked publications 21 DOIs Primary publication Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation. Arthritis research & therapy, 2014 PubMed DOI Related publications The Integration of Bioinformatics with Experimental Validation Has Uncovered Shared Molecular Characteristics Between Sarcopenia and Osteoarthritis. Calcified tissue international, 2026 PubMed DOI Identification of potential key efferocytosis-related genes in rheumatoid arthritis using machine learning. Clinical rheumatology, 2026 PubMed DOI Aquaporin-1 stabilizes β-catenin to promote NLRP3 inflammasome-mediated pyroptosis in rheumatoid arthritis. Apoptosis : an international journal on programmed cell death, 2026 PubMed DOI CD27 Neutralization Attenuates Rheumatoid Arthritis by Suppressing. Biochemical genetics, 2026 PubMed DOI G protein-coupled receptor-related genes matrix metallopeptidase 9 and tachykinin precursor 1 promote osteoarthritis progression and influence the immune microenvironment. International journal of biological macromolecules, 2025 PubMed DOI Identification of key pathways and biomarkers in rheumatoid arthritis synovial tissue through comprehensive transcriptomic integration. Journal of orthopaedics, 2026 PubMed DOI Celastrol suppresses bone destruction in rheumatoid arthritis by inhibiting ALOX5 expression in macrophages via the NF-κB pathway. Scientific reports, 2025 PubMed DOI Elucidation of hub cross-talk genes as potential biomarkers and drug prediction for chronic periodontitis and rheumatoid arthritis: A bioinformatics analysis. Medicine, 2025 PubMed DOI Identification of differential expressed genes common to rheumatoid arthritis and osteoporosis based on GEO database. Medicine, 2025 PubMed DOI Integrative transcriptomic analysis identifies synovium-derived biomarkers for OA-related synovitis and builds a validated diagnostic nomogram. Medicine, 2026 PubMed DOI Identification of Autophagy-Associated Molecular Signatures in Osteoarthritis Revealed by Integrative Multi-Omics and Experimental Validation. Chemical biology & drug design, 2026 PubMed DOI STAT1 transcriptionally activates CXCL13 to promote cell inflammation and proliferation and inhibit cell apoptosis in rheumatoid arthritis fibroblast-like synoviocytes. Journal of orthopaedic surgery and research, 2026 PubMed DOI Programmed cell death-related gene S100A9 promotes macrophage M1 polarization and chondrocyte apoptosis in rheumatoid arthritis. Biology direct, 2026 PubMed DOI [Identification of efferocytosis-related genes in osteoarthritis and prediction of traditional Chinese medicines based on bioinformatics and machine learning]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2026 PubMed DOI Identification of common genes and biomarkers between Dermatomyositis and rheumatoid arthritis through integrated bioinformatics. PloS one, 2026 PubMed DOI KIF11 promotes rheumatoid arthritis pathogenesis by activating M1 macrophage polarization and promoting inflammatory cytokine secretion. PloS one, 2026 PubMed DOI Bmal1 Attenuates Collagen-Induced Arthritis by Regulating Macrophage Polarization via Sirt1. Journal of inflammation research, 2026 PubMed DOI Immune cells with senescence-related transcriptional signatures orchestrate the inflammatory continuum in osteoarthritis synovium: a single-cell and machine learning study. Frontiers in immunology, 2026 PubMed DOI Identification and validation of SUMOylation-related key genes for osteoarthritis through integration of single-cell, bulk RNA sequencing and animal model experiments. Frontiers in medicine, 2026 PubMed DOI Mendelian Randomization and Transcriptome Analyses Reveal Important Roles for CEBPB and CX3CR1 in Osteoarthritis. Bioengineering (Basel, Switzerland), 2025 PubMed DOI	Available

Metadata Quality Components

Persisted metadata quality

100 pts

Clarity: 100%
Weight: 100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review

97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Tumor vs normal

Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
Disease context Rheumatoid arthritis Disease context came from Normalization rules.
Likely case group Osteoarthritis 20 samples
Likely control group Healthy control 10 samples

Intent Interpretation

Downgrade or exclusion reason Downgraded assay: microarray cohorts are separated from the RNA-seq intent. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

Comparison: Disease/model vs control. Specimen: Tissue. Comparison suitability: 0%.
Interpreted disease metadata: Rheumatoid arthritis.
Processed data is available for downstream review.
External evidence: Expression Atlas curated experiment link is available.
External evidence: PubMed links 21 publications; 21 DOIs available: PMID 24690414, PMID 40885352, PMID 40958328, PMID 41007174, PMID 41209768.
Publication context: Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.. Arthritis research & therapy, 2014. PMID 24690414. DOI 10.1186/ar4526.
Publication context: G protein-coupled receptor-related genes matrix metallopeptidase 9 and tachykinin precursor 1 promote osteoarthritis progression and influence the immune microenvironment.. International journal of biological macromolecules, 2025. PMID 40885352. DOI 10.1016/j.ijbiomac.2025.147208.
Publication context: Elucidation of hub cross-talk genes as potential biomarkers and drug prediction for chronic periodontitis and rheumatoid arthritis: A bioinformatics analysis.. Medicine, 2025. PMID 40958328. DOI 10.1097/MD.0000000000044358.
Publication context: 18 additional linked PubMed publications are available.

Cautions

Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
Microarray expression context downgraded below primary bulk RNA-seq for the default tissue ranking.
Overall score capped because comparison suitability is weak for the selected search intent.
Overall score capped because microarray cohorts should be compared separately from RNA-seq cohorts.
Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Microarray expression context was detected; compare separately from RNA-seq cohorts.
Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis.
Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Normalized Fields

104 fields

Field Value Source Derived by Confidence Evidence Reason

anatomical_source synovium GSM1332201 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332202 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332203 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332204 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332205 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332206 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332207 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332208 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332209 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332210 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332211 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332212 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332213 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332214 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332215 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332216 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332217 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332218 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332219 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332220 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332221 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332222 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332223 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332224 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332225 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332226 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332227 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332228 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332229 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

anatomical_source synovium GSM1332230 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence synovial tissue: synovial tissue isolated from joint sample-anatomical-source-v1 sample-local anatomical source

assay_type microarray GSE55235 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence microarray dataset_accession: GSE55235 dataset_title: Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation organism: Homo sapiens a... keyword match keyword match: microarray

control_type healthy control GSM1332201 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 1 (ND_1) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332202 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 2 (ND_2) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332203 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 3 (ND_3) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332204 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 4 (ND_4) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332205 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 5 (ND_5) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332206 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 6 (ND_6) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332207 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 7 (ND_7) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332208 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 8 (ND_8) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332209 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 9 (ND_9) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

control_type healthy control GSM1332210 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 10 (ND_10) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary control type match: healthy control

disease rheumatoid arthritis GSE55235 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis dataset_accession: GSE55235 dataset_title: Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation organism: Homo sapiens a... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332221 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 1 (RA_1) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332222 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 2 (RA_2) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332223 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 3 (RA_3) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332224 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 4 (RA_4) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332225 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 5 (RA_5) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332226 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 6 (RA_6) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332227 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 7 (RA_7) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332228 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 8 (RA_8) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332229 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 9 (RA_9) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

disease rheumatoid arthritis GSM1332230 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence rheumatoid arthritis Synovial tissue from rheumatoid arthritis joint 10 (RA_10) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated ... controlled vocabulary controlled vocabulary disease match: rheumatoid arthritis

normal_tissue_type healthy donor tissue GSM1332201 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 1 (ND_1) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332202 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 2 (ND_2) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332203 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 3 (ND_3) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332204 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 4 (ND_4) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332205 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 5 (ND_5) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332206 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 6 (ND_6) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332207 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 7 (ND_7) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332208 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 8 (ND_8) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332209 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 9 (ND_9) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

normal_tissue_type healthy donor tissue GSM1332210 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 10 (ND_10) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary normal tissue type match: healthy control

organism Homo sapiens GSE55235 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence homo sapiens dataset_accession: GSE55235 dataset_title: Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation organism: Homo sapiens a... keyword match keyword match: homo sapiens

sample_type normal tissue GSM1332201 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 1 (ND_1) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332202 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 2 (ND_2) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332203 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 3 (ND_3) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332204 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 4 (ND_4) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332205 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 5 (ND_5) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332206 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 6 (ND_6) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332207 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 7 (ND_7) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332208 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 8 (ND_8) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332209 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 9 (ND_9) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

sample_type normal tissue GSM1332210 Runtime Siftome inference UNRESOLVED / UNREVIEWED high confidence healthy control Synovial tisssue from healthy joint 10 (ND_10) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary sample type match: healthy control

tissue synovium GSE55235 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial dataset_accession: GSE55235 dataset_title: Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation organism: Homo sapiens a... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332201 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 1 (ND_1) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332202 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 2 (ND_2) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332203 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 3 (ND_3) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332204 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 4 (ND_4) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332205 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 5 (ND_5) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332206 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 6 (ND_6) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332207 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 7 (ND_7) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332208 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 8 (ND_8) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332209 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 9 (ND_9) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332210 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tisssue from healthy joint 10 (ND_10) synovial tissue from healthy joint disease state: healthy control; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332211 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 1 (OA_1) synovial tissue from osteoarthritic joint disease state: osteoarthritis; tissue: synovial tissue isolated from joint controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332212 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 2 (OA_2) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332213 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 3 (OA_3) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332214 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 4 (OA_4) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332215 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 5 (OA_5) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332216 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 6 (OA_6) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332217 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 7 (OA_7) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332218 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 8 (OA_8) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332219 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 9 (OA_9) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovial ... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332220 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from osteoarthritic joint 10 (OA_10) synovial tissue from osteoarthritic joint disease state: synovial tissue isolated from osteoarthritic joint; tissue: synovia... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332221 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 1 (RA_1) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332222 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 2 (RA_2) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332223 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 3 (RA_3) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332224 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 4 (RA_4) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332225 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 5 (RA_5) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332226 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 6 (RA_6) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332227 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 7 (RA_7) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332228 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 8 (RA_8) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332229 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 9 (RA_9) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated fr... controlled vocabulary controlled vocabulary tissue match: synovial

tissue synovium GSM1332230 Runtime Siftome inference UNRESOLVED / UNREVIEWED medium confidence synovial Synovial tissue from rheumatoid arthritis joint 10 (RA_10) synovial tissue from rheumatoid arthritis joint disease state: rheumatoid arthritis; tissue: synovial tissue isolated ... controlled vocabulary controlled vocabulary tissue match: synovial

Sample Group Preview

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Study totals: Case 20 | Control 10 | Unassigned 0 | Excluded 0 | Ambiguous 0 30 rows shown

Group	Role	Accession	Title	Source / characteristics	Reason
Osteoarthritis	Case	GSM1332211	Synovial tissue from osteoarthritic joint 1 (OA_1)	Synovial tissue from osteoarthritic joint Disease state: Osteoarthritis; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332212	Synovial tissue from osteoarthritic joint 2 (OA_2)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332213	Synovial tissue from osteoarthritic joint 3 (OA_3)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332214	Synovial tissue from osteoarthritic joint 4 (OA_4)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332215	Synovial tissue from osteoarthritic joint 5 (OA_5)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332216	Synovial tissue from osteoarthritic joint 6 (OA_6)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332217	Synovial tissue from osteoarthritic joint 7 (OA_7)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332218	Synovial tissue from osteoarthritic joint 8 (OA_8)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332219	Synovial tissue from osteoarthritic joint 9 (OA_9)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Synovial tissue isolated from osteoarthritic joint	Case	GSM1332220	Synovial tissue from osteoarthritic joint 10 (OA_10)	Synovial tissue from osteoarthritic joint Disease state: Synovial tissue isolated from osteoarthritic joint; Tissue: Synovial tissue isolated from joint	Explicit characteristic comparison arm detected.
Rheumatoid arthritis	Case	GSM1332221	Synovial tissue from rheumatoid arthritis joint 1 (RA_1)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332222	Synovial tissue from rheumatoid arthritis joint 2 (RA_2)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332223	Synovial tissue from rheumatoid arthritis joint 3 (RA_3)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332224	Synovial tissue from rheumatoid arthritis joint 4 (RA_4)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332225	Synovial tissue from rheumatoid arthritis joint 5 (RA_5)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332226	Synovial tissue from rheumatoid arthritis joint 6 (RA_6)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332227	Synovial tissue from rheumatoid arthritis joint 7 (RA_7)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332228	Synovial tissue from rheumatoid arthritis joint 8 (RA_8)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332229	Synovial tissue from rheumatoid arthritis joint 9 (RA_9)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Rheumatoid arthritis	Case	GSM1332230	Synovial tissue from rheumatoid arthritis joint 10 (RA_10)	Synovial tissue from rheumatoid arthritis joint Disease state: Rheumatoid arthritis; Tissue: Synovial tissue isolated from joint	Case marker detected.
Healthy control	Control	GSM1332201	Synovial tisssue from healthy joint 1 (ND_1)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332202	Synovial tisssue from healthy joint 2 (ND_2)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332203	Synovial tisssue from healthy joint 3 (ND_3)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332204	Synovial tisssue from healthy joint 4 (ND_4)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332205	Synovial tisssue from healthy joint 5 (ND_5)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332206	Synovial tisssue from healthy joint 6 (ND_6)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332207	Synovial tisssue from healthy joint 7 (ND_7)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332208	Synovial tisssue from healthy joint 8 (ND_8)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332209	Synovial tisssue from healthy joint 9 (ND_9)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.
Healthy control	Control	GSM1332210	Synovial tisssue from healthy joint 10 (ND_10)	Synovial tissue from healthy joint Disease state: Healthy control; Tissue: Synovial tissue isolated from joint	Sample-local control marker detected.

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External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.

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Use as Discovery Cohort