GSE65682

Genome-wide blood transcriptional profiling in critically ill patients - MARS consortium

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Source
GEO
Assay
microarray
Organism
Homo sapiens
Whole-study samples
802 samples
Specimen
Biofluid
Reported/interpreted study design
Disease/model vs control Design classification does not establish patient pairs.
Comparison type
Tumor vs normal
Contributors
Scicluna BP, van der Poll T, Scicluna B
Contact name
Brendon Scicluna
Submission date
2015-02-05
Last update
2023-11-16
Organization
University of Malta
Department
Not available
Public date
2015-07-06
Experiment types
Expression profiling by array
Platforms
GPL13667 [HG-U219] Affymetrix Human Genome U219 Array
Series type
Series
SubSeries
Not available
BioProject
PRJNA274706

Summary

The host response in critically ill patients with sepsis, septic shock remains poorly defined. Considerable research has been conducted to accurately distinguish patients with sepsis from those with non-infectious causes of disease. Technological innovations have positioned systems biology at the forefront of biomarker discovery. Analysis of the whole-blood leukocyte transcriptome enables the assessment of thousands of molecular signals beyond simply measuring several proteins in plasma, which for use as biomarkers is important since combinations of biomarkers likely provide more diagnostic accuracy than the measurement of single ones or a few. Evidence suggests that genome-wide transcriptional profiling of blood leukocytes can assist in differentiating between infection and non-infectious causes of severe disease. Of importance, RNA biomarkers have the potential advantage that they can be measured reliably in rapid quantitative reverse transcriptase polymerase chain reaction (qRT-PCR)-based point of care tests.

Overall design

PAXgene blood RNA was isolated at intensive-care unit (ICU) admission and throughout ICU length-of-stay. Through the use of genome-wide microarrays we aimed to identify molecular features that enbale the adequate discrimination of infectious and non-infectious sources of critical illness. Patient diagnoses include community-acquired pneumonia (cap), hospital-acquired pneumonia (hap) and non-infectious cap control patients (no-cap) (characteristics: pneumonia diagnoses). The influence of variable degrees of thrombocytopenia were also assessed (characteristics: thrombocytopenia).

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
802 GSM samples
 Primary source
recount3

Planned trusted source for processed count availability.

 No match found
Expression Atlas

Planned source for curated expression experiment links.

 No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

36 linked publications 36 DOIs

Primary publication

  1. Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study. Intensive care medicine, 2020
  2. Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study. Intensive care medicine, 2022
  3. Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes. Intensive care medicine, 2023
  4. Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. The Lancet. Respiratory medicine, 2017
  5. Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nature immunology, 2016
  6. A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission. American journal of respiratory and critical care medicine, 2015
  7. Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients. American journal of respiratory and critical care medicine, 2016
  8. Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission. American journal of respiratory and critical care medicine, 2018
  9. Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles. American journal of respiratory and critical care medicine, 2019
  10. Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients. Blood, 2016
  11. Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients. Critical care (London, England), 2016
  12. Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission? Critical care (London, England), 2019
  13. Association between age and the host response in critically ill patients with sepsis. Critical care (London, England), 2022
  14. The host response in critically ill sepsis patients on statin therapy: a prospective observational study. Annals of intensive care, 2018
  15. The Impact of HIV Co-Infection on the Genomic Response to Sepsis. PloS one, 2016
  16. Combined Transcriptome and Proteome Leukocyte's Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis. Frontiers in immunology, 2021

Related publications

  1. NLK facilitates Caspase-8 activation to drive macrophage PANoptosis in sepsis. Clinical and translational medicine, 2026
  2. Sepsis Endotypes Defined by Lymphocyte Thresholds and Inflammation Inform Precision Immunomodulation. MedComm, 2026
  3. PRC1 promotes immunosuppressive macrophages in sepsis via β-catenin/STAT3 signaling. Cellular and molecular life sciences : CMLS, 2026
  4. Systematic characterization of pyroptosis-related gene patterns identifies potential prognostic inflammatory phenotypes in sepsis. Functional & integrative genomics, 2026
  5. Knockdown of PTEN Inhibits Autophagy-Dependent Ferroptosis to Alleviate LPS-Induced Sepsis-Associated Acute Kidney Injury. Inflammation, 2026
  6. Autophagy-driven CCL7+ monocyte terminal differentiation program fuels CD8+ T cell-mediated cardiac injury in Sepsis. International immunopharmacology, 2026
  7. Screening of Sepsis Diagnostic Biomarkers Based on Fumarate Metabolism-Related Genes with Analysis of Immune Infiltration and Subtype Identification. Immunological investigations, 2026
  8. Identification of Molecular Subtypes and Prognostic Characteristics in Sepsis Based on T-Helper 17 Cell Differentiation-Related Genes. Shock (Augusta, Ga.), 2026
  9. Immunomodulatory Roles and Clinical Significance of GZMM and DDX24 in Sepsis: A Multiomics Integrative Analysis With Experimental Validation. Human mutation, 2026
  10. Identification of potential characteristic genes in sepsis utilizing RNA sequencing and gene silence. BMC immunology, 2025
  11. Unravelling butyrate metabolism in sepsis: identification of key genes. BMC infectious diseases, 2025
  12. Integrative multi-omics and machine learning identify mitochondrial biomarkers for pathogen-specific sepsis stratification and translational prioritization. European journal of medical research, 2026
  13. Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis. PloS one, 2025
  14. ICU-acquired infections and mortality in community-acquired pneumonia-induced sepsis: Insights from a transcriptomic analysis. PloS one, 2026
  15. Multi-Dimensional Characterization of Programmed Cell Death Patterns for Prognostic Stratification and Therapeutic Insights in Sepsis. ImmunoTargets and therapy, 2025
  16. Evaluating the Diagnostic Value and Molecular Mechanism of Energy Metabolism-Related Gene PEA15 in Sepsis. Journal of inflammation research, 2026
  17. Bioinformatics-based screening and validation of ferroptosis-related genes in sepsis and type 2 diabetes mellitus. Experimental biology and medicine (Maywood, N.J.), 2025
  18. Machine learning identifies PPARG as a diagnostic biomarker for sepsis linked to CD14/NF-κB signaling: integrated transcriptomics and experimental validation. Frontiers in cellular and infection microbiology, 2026
  19. Development of a prognostic model for sepsis based on gut microbiota-associated genes and identification of potential targets. Frontiers in medicine, 2026
  20. Bioinformatics analysis identifies IL-23A and JAK2 as regulatory factors in sepsis immune response via the JAK/STAT3 pathway. Journal of infection in developing countries, 2026
Available

Metadata Quality Components

Persisted metadata quality

100 pts
Clarity
100%
Weight
100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Anatomical source metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Analysis Readiness

Ready after review
97% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

No readiness blockers detected.

Next Steps

  • Verify the proposed sample assignments and case-versus-control comparison against the GEO metadata before using them in DESeq2 or another differential-expression tool.
  • Confirm processed count files and sample identifiers match the exported metadata.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Review the grouping table for biologically meaningful differences that the automated checks may not detect.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Tumor vs normal
Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
  • Disease context Sepsis, septic shock Disease context came from Normalization rules.
  • Likely case group Sepsis 776 samples
  • Likely control group Normal tissue 26 samples

Intent Interpretation

  • Downgrade or exclusion reason Downgraded for tissue search because it is a biofluid cohort. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Comparison: Disease/model vs control. Specimen: Biofluid. Comparison suitability: 0%.
  • Interpreted disease metadata: Infectious disease or host response, Metabolic disease, Sepsis, Septic shock.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 36 publications; 36 DOIs available: PMID 26121490, PMID 26871709, PMID 26950237, PMID 26956172, PMID 27267747.
  • Publication context: A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission.. American journal of respiratory and critical care medicine, 2015. PMID 26121490. DOI 10.1164/rccm.201502-0355OC.
  • Publication context: The Impact of HIV Co-Infection on the Genomic Response to Sepsis.. PloS one, 2016. PMID 26871709. DOI 10.1371/journal.pone.0148955.
  • Publication context: Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.. Nature immunology, 2016. PMID 26950237. DOI 10.1038/ni.3398.
  • Publication context: 33 additional linked PubMed publications are available.

Cautions

  • Downgraded for tissue search because it is a biofluid cohort.
  • Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
  • Disease/control design without a tumor/normal comparison is outside tumor/normal triage.
  • Blood, plasma, or serum cohort downgraded because this ranking targets tissue tumor-vs-normal comparisons.
  • Microarray expression context downgraded below primary bulk RNA-seq for the default tissue ranking.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Overall score capped because microarray cohorts should be compared separately from RNA-seq cohorts.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Normalized Fields

showing 500 of 3239 fields

Sample Group Preview

showing 76 of 802 preview rows Show Hide
Study totals: Case 776 | Control 26 | Unassigned 0 | Excluded 0 | Ambiguous 0 showing 76 of 802 preview rows
Group Role Accession Title Source / characteristics Reason
Sepsis Case GSM1602801 Intensive-care unit patient [03_04_2013_B02_3270] Whole blood Gender: Male; Age: 64; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602802 Intensive-care unit patient [03_04_2013_B06_1793] Whole blood Gender: Female; Age: 46; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602803 Intensive-care unit patient [03_04_2013_B07_3252] Whole blood Gender: Male; Age: 69; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602804 Intensive-care unit patient [03_04_2013_B08_3242] Whole blood Gender: Male; Age: 60; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602805 Intensive-care unit patient [03_04_2013_C08_2736] Whole blood Gender: Female; Age: 64; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602806 Intensive-care unit patient [03_04_2013_E06_526] Whole blood Gender: Male; Age: 54; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602807 Healthy subject [03_04_2013_E09_hv59] Whole blood Gender: Male; Age: 31; Pneumonia diagnoses: NA; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: Healthy; Icu_acquired_infection_paired: Healthy; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602808 Intensive-care unit patient [03_04_2013_F02_2618] Whole blood Gender: Male; Age: 59; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602809 Healthy subject [03_04_2013_F10_hv49] Whole blood Gender: Male; Age: 26; Pneumonia diagnoses: NA; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: Healthy; Icu_acquired_infection_paired: Healthy; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602810 Intensive-care unit patient [03_04_2013_G07_3147] Whole blood Gender: Male; Age: 77; Pneumonia diagnoses: Cap; Thrombocytopenia: C_low; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602811 Intensive-care unit patient [03_04_2013_H02_2404] Whole blood Gender: Female; Age: 63; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars4; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602812 Intensive-care unit patient [03_04_2013_H05_544] Whole blood Gender: Female; Age: 71; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602813 Intensive-care unit patient [03_04_2013_H09_2480] Whole blood Gender: Female; Age: 73; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 1; Time_to_event_28days: 4; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602814 Intensive-care unit patient [05_03_2013_A03_2572276] Whole blood Gender: Female; Age: 59; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602816 Intensive-care unit patient [05_03_2013_B05_2590193] Whole blood Gender: Female; Age: 84; Pneumonia diagnoses: Cap; Thrombocytopenia: C_low; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602817 Intensive-care unit patient [05_03_2013_B12_2165] Whole blood Gender: Male; Age: 67; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602818 Intensive-care unit patient [05_03_2013_C04_2405776] Whole blood Gender: Male; Age: 62; Pneumonia diagnoses: Cap; Thrombocytopenia: B_medium_low; Endotype_cohort: Validation; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602819 Intensive-care unit patient [05_03_2013_C06_2404709] Whole blood Gender: Male; Age: 71; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: ADMIS_NO_ICUAI; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602820 Intensive-care unit patient [05_03_2013_C12_2123] Whole blood Gender: Male; Age: 61; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602821 Intensive-care unit patient [05_03_2013_D01_383] Whole blood Gender: Female; Age: 67; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602822 Intensive-care unit patient [05_03_2013_E11_605] Whole blood Gender: Male; Age: 32; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602823 Intensive-care unit patient [05_03_2013_F01_2177356] Whole blood Gender: Male; Age: 52; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars1; Mortality_event_28days: 1; Time_to_event_28days: 17; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602824 Intensive-care unit patient [05_03_2013_G02_2106085] Whole blood Gender: Male; Age: 32; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602825 Intensive-care unit patient [05_03_2013_H09_1052] Whole blood Gender: Female; Age: 78; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602826 Intensive-care unit patient [06_02_2013_C05_2095] Whole blood Gender: Male; Age: 70; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: Admis_ICUAI; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602827 Intensive-care unit patient [06_02_2013_E04_218] Whole blood Gender: Female; Age: 62; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602828 Intensive-care unit patient [06_02_2013_F02_2669401] Whole blood Gender: Female; Age: 54; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602829 Intensive-care unit patient [06_02_2013_F04_2664986] Whole blood Gender: Male; Age: 63; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602830 Intensive-care unit patient [06_02_2013_F11_1498] Whole blood Gender: Male; Age: 47; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602831 Intensive-care unit patient [06_02_2013_F12_2586738] Whole blood Gender: Male; Age: 79; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602833 Intensive-care unit patient [06_02_2013_G02_2709216] Whole blood Gender: Female; Age: 28; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602834 Intensive-care unit patient [06_02_2013_H03_2731081] Whole blood Gender: Male; Age: 81; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602835 Intensive-care unit patient [07_03_2013_A04_1171] Whole blood Gender: Male; Age: 63; Pneumonia diagnoses: No-cap; Thrombocytopenia: NA; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602836 Intensive-care unit patient [07_03_2013_A11_2000] Whole blood Gender: Male; Age: 67; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602837 Intensive-care unit patient [07_03_2013_B09_2107380] Whole blood Gender: Male; Age: 25; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602838 Intensive-care unit patient [07_03_2013_B10_2545687] Whole blood Gender: Male; Age: 50; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602839 Intensive-care unit patient [07_03_2013_C09_2684834] Whole blood Gender: Male; Age: 84; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 12; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602840 Intensive-care unit patient [07_03_2013_F02_1695] Whole blood Gender: Female; Age: 18; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602841 Intensive-care unit patient [07_03_2013_F08_2757591] Whole blood Gender: Female; Age: 68; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602842 Intensive-care unit patient [07_03_2013_G02_873] Whole blood Gender: Female; Age: 64; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602843 Intensive-care unit patient [07_03_2013_G12_1272] Whole blood Gender: Female; Age: 48; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars4; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602844 Intensive-care unit patient [07_03_2013_H01_1281] Whole blood Gender: Male; Age: 76; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 7; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602845 Intensive-care unit patient [12_03_2013_A07_2463040] Whole blood Gender: Male; Age: 58; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602846 Intensive-care unit patient [12_03_2013_B04_2459139] Whole blood Gender: Male; Age: 21; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602847 Intensive-care unit patient [12_03_2013_E10_643] Whole blood Gender: Male; Age: 43; Pneumonia diagnoses: Cap; Thrombocytopenia: A_very_low; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602848 Intensive-care unit patient [12_03_2013_G10_2028] Whole blood Gender: Male; Age: 61; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602849 Intensive-care unit patient [12_03_2013_H12_602] Whole blood Gender: Male; Age: 74; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars4; Mortality_event_28days: 1; Time_to_event_28days: 11; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602851 Intensive-care unit patient [13_02_2013_B06_2262695] Whole blood Gender: Female; Age: 85; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 1; Time_to_event_28days: 14; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602852 Intensive-care unit patient [13_02_2013_B10_1521] Whole blood Gender: Female; Age: 26; Pneumonia diagnoses: Cap; Thrombocytopenia: A_very_low; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: Admis_ICUAI; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Case marker detected.
Sepsis Case GSM1602853 Intensive-care unit patient [13_02_2013_C12_338] Whole blood Gender: Female; Age: 72; Pneumonia diagnoses: Cap; Thrombocytopenia: NA; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Case marker detected.
726 additional case samples are hidden from this preview.
Normal tissue Control GSM1602815 Intensive-care unit patient [05_03_2013_A10_408] Whole blood Gender: Female; Age: 61; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602832 Intensive-care unit patient [06_02_2013_G01_2392950] Whole blood Gender: Female; Age: 61; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602850 Intensive-care unit patient [13_02_2013_A08_2138225] Whole blood Gender: Male; Age: 25; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602858 Intensive-care unit patient [13_03_2013_A05_2311555] Whole blood Gender: Male; Age: 53; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 15; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: Admis_ICUAI; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602863 Intensive-care unit patient [13_03_2013_F11_2862824] Whole blood Gender: Female; Age: 72; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 1; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602902 Intensive-care unit patient [19_03_2013_F05_2047294] Whole blood Gender: Male; Age: 66; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1602946 Intensive-care unit patient [22_01_2013_H10_2428168] Whole blood Gender: Male; Age: 77; Pneumonia diagnoses: Cap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 8; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1691911 Intensive-care unit patient [03_04_2013_H04_2814] Whole blood Gender: Female; Age: 45; Pneumonia diagnoses: Hap; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1691927 Intensive-care unit patient [05_03_2013_C05_2279394] Whole blood Gender: Female; Age: 75; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: Admis_ICUAI; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1691980 Intensive-care unit patient [06_02_2013_A12_1494] Whole blood Gender: Female; Age: 77; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: Abdo_s Control marker detected.
Normal tissue Control GSM1692034 Intensive-care unit patient [07_03_2013_B03_2516790] Whole blood Gender: Female; Age: 52; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692055 Intensive-care unit patient [07_03_2013_D11_2079794] Whole blood Gender: Female; Age: 73; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars4; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692058 Intensive-care unit patient [07_03_2013_E05_2305248] Whole blood Gender: Male; Age: 50; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692099 Intensive-care unit patient [12_03_2013_B12_2328205] Whole blood Gender: Male; Age: 56; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars4; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692130 Intensive-care unit patient [12_03_2013_H02_2791031] Whole blood Gender: Female; Age: 66; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692158 Intensive-care unit patient [13_02_2013_E07_262] Whole blood Gender: Male; Age: 36; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars4; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692165 Intensive-care unit patient [13_02_2013_F09_554] Whole blood Gender: Male; Age: 78; Pneumonia diagnoses: Hap; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692174 Intensive-care unit patient [13_02_2013_H06_638] Whole blood Gender: Male; Age: 63; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692216 Intensive-care unit patient [13_03_2013_F10_2805753] Whole blood Gender: Male; Age: 48; Pneumonia diagnoses: Hap; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars3; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692244 Intensive-care unit patient [14_03_2013_D01_1908] Whole blood Gender: Male; Age: 77; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 1; Time_to_event_28days: 7; Icu_acquired_infection: NA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692255 Intensive-care unit patient [14_03_2013_F02_879] Whole blood Gender: Male; Age: 64; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars1; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: Abdo_s Control marker detected.
Normal tissue Control GSM1692299 Intensive-care unit patient [19_03_2013_F09_2197135] Whole blood Gender: Female; Age: 69; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Validation; Endotype_class: Mars1; Mortality_event_28days: 1; Time_to_event_28days: 21; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692343 Intensive-care unit patient [20_03_2013_F05_922] Whole blood Gender: Male; Age: 64; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 1; Time_to_event_28days: 8; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692386 Intensive-care unit patient [21_03_2013_E03_2532] Whole blood Gender: Male; Age: 58; Pneumonia diagnoses: Hap; Thrombocytopenia: D_normal; Endotype_cohort: Discovery; Endotype_class: Mars2; Mortality_event_28days: 0; Time_to_event_28days: 28; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692456 Intensive-care unit patient [26_03_2013_B02_2077005] Whole blood Gender: Male; Age: 59; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: No_DM; Abdominal_sepsis_and_controls: NA Control marker detected.
Normal tissue Control GSM1692481 Intensive-care unit patient [27_03_2013_C02_171] Whole blood Gender: Male; Age: 60; Pneumonia diagnoses: NA; Thrombocytopenia: D_normal; Endotype_cohort: NA; Endotype_class: NA; Mortality_event_28days: NA; Time_to_event_28days: NA; Icu_acquired_infection: No_ICUA; Icu_acquired_infection_paired: NA; Diabetes_mellitus: NA; Abdominal_sepsis_and_controls: NA Control marker detected.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.