Matching samples

GSE69446 · Impact of NOD2 Genotype on the Innate Monocyte Transcriptome in Crohn’s Disease

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

14 case / 14 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (28)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

GSM1701327

Uncertain

RNA-seq CD NOD2 after MDP, replicate1

Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Insufficient evidence
        • The required value is not reported.
        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
          • Supported by the indexed evidence.
          • specimen category excludes: Biofluid — Meets requirement
            • Supported by the indexed evidence.
            Source metadata
            Source name
            Monocytes, CD, NOD2 SNP, stimulated with MDP
            Characteristics
            cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
            Description
            Not reported
            Indexed organism evidence
            INFERRED · PARENT_INHERITED: Not reported
            Indexed assay evidence
            INFERRED · PARENT_INHERITED: Not reported
            Source
            GEO
            Original indexed metadata
            sample_accession: GSM1701327
            sample_title: RNA-seq CD NOD2 after MDP, replicate1
            source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
            characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

            GSM1701328

            Uncertain

            RNA-seq CD NOD2 after MDP, replicate2

            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

            Requirements and decision evidence
            • organism: Homo sapiens — Insufficient evidence
              • The required value is not reported.
              • assay type: bulk RNA-seq — Insufficient evidence
                • The required value is not reported.
                • specimen category: Tissue or biopsy — Insufficient evidence
                  • The required value is not reported.
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Meets requirement
                      • Supported by the indexed evidence.
                      Source metadata
                      Source name
                      Monocytes, CD, NOD2 SNP, stimulated with MDP
                      Characteristics
                      cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                      Description
                      Not reported
                      Indexed organism evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Indexed assay evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Source
                      GEO
                      Original indexed metadata
                      sample_accession: GSM1701328
                      sample_title: RNA-seq CD NOD2 after MDP, replicate2
                      source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
                      characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                      GSM1701329

                      Uncertain

                      RNA-seq CD NOD2 after MDP, replicate3

                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                      Requirements and decision evidence
                      • organism: Homo sapiens — Insufficient evidence
                        • The required value is not reported.
                        • assay type: bulk RNA-seq — Insufficient evidence
                          • The required value is not reported.
                          • specimen category: Tissue or biopsy — Insufficient evidence
                            • The required value is not reported.
                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                              • Supported by the indexed evidence.
                              • specimen category excludes: Biofluid — Meets requirement
                                • Supported by the indexed evidence.
                                Source metadata
                                Source name
                                Monocytes, CD, NOD2 SNP, stimulated with MDP
                                Characteristics
                                cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                Description
                                Not reported
                                Indexed organism evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Indexed assay evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Source
                                GEO
                                Original indexed metadata
                                sample_accession: GSM1701329
                                sample_title: RNA-seq CD NOD2 after MDP, replicate3
                                source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
                                characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                GSM1701330

                                Uncertain

                                RNA-seq CD NOD2 before MDP, replicate1

                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                Requirements and decision evidence
                                • organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                      • The required value is not reported.
                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                        • Supported by the indexed evidence.
                                        • specimen category excludes: Biofluid — Meets requirement
                                          • Supported by the indexed evidence.
                                          Source metadata
                                          Source name
                                          Monocytes, CD, NOD2 SNP, unstimulated
                                          Characteristics
                                          cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: unstimulated
                                          Description
                                          Not reported
                                          Indexed organism evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Indexed assay evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Source
                                          GEO
                                          Original indexed metadata
                                          sample_accession: GSM1701330
                                          sample_title: RNA-seq CD NOD2 before MDP, replicate1
                                          source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                          characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: unstimulated

                                          GSM1701331

                                          Uncertain

                                          RNA-seq CD NOD2 before MDP, replicate2

                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                          Requirements and decision evidence
                                          • organism: Homo sapiens — Insufficient evidence
                                            • The required value is not reported.
                                            • assay type: bulk RNA-seq — Insufficient evidence
                                              • The required value is not reported.
                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                • The required value is not reported.
                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • specimen category excludes: Biofluid — Meets requirement
                                                    • Supported by the indexed evidence.
                                                    Source metadata
                                                    Source name
                                                    Monocytes, CD, NOD2 SNP, unstimulated
                                                    Characteristics
                                                    cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: unstimulated
                                                    Description
                                                    Not reported
                                                    Indexed organism evidence
                                                    INFERRED · PARENT_INHERITED: Not reported
                                                    Indexed assay evidence
                                                    INFERRED · PARENT_INHERITED: Not reported
                                                    Source
                                                    GEO
                                                    Original indexed metadata
                                                    sample_accession: GSM1701331
                                                    sample_title: RNA-seq CD NOD2 before MDP, replicate2
                                                    source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                                    characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: unstimulated

                                                    GSM1701332

                                                    Uncertain

                                                    RNA-seq CD NOD2 before MDP, replicate3

                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                    Requirements and decision evidence
                                                    • organism: Homo sapiens — Insufficient evidence
                                                      • The required value is not reported.
                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                        • The required value is not reported.
                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                          • The required value is not reported.
                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                            • Supported by the indexed evidence.
                                                            • specimen category excludes: Biofluid — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              Source metadata
                                                              Source name
                                                              Monocytes, CD, NOD2 SNP, unstimulated
                                                              Characteristics
                                                              cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: unstimulated
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM1701332
                                                              sample_title: RNA-seq CD NOD2 before MDP, replicate3
                                                              source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                                              characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: unstimulated

                                                              GSM1701333

                                                              Uncertain

                                                              RNA-seq CD WT after MDP, replicate1

                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                              Requirements and decision evidence
                                                              • organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                    • The required value is not reported.
                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                      • Supported by the indexed evidence.
                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                        • Supported by the indexed evidence.
                                                                        Source metadata
                                                                        Source name
                                                                        Monocytes, CD, WT, stimulated with MDP
                                                                        Characteristics
                                                                        cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                        Description
                                                                        Not reported
                                                                        Indexed organism evidence
                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                        Indexed assay evidence
                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                        Source
                                                                        GEO
                                                                        Original indexed metadata
                                                                        sample_accession: GSM1701333
                                                                        sample_title: RNA-seq CD WT after MDP, replicate1
                                                                        source_name: Monocytes, CD, WT, stimulated with MDP
                                                                        characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                        GSM1701334

                                                                        Uncertain

                                                                        RNA-seq CD WT after MDP, replicate2

                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                        Requirements and decision evidence
                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                          • The required value is not reported.
                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                  • Supported by the indexed evidence.
                                                                                  Source metadata
                                                                                  Source name
                                                                                  Monocytes, CD, WT, stimulated with MDP
                                                                                  Characteristics
                                                                                  cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                  Description
                                                                                  Not reported
                                                                                  Indexed organism evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Indexed assay evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Source
                                                                                  GEO
                                                                                  Original indexed metadata
                                                                                  sample_accession: GSM1701334
                                                                                  sample_title: RNA-seq CD WT after MDP, replicate2
                                                                                  source_name: Monocytes, CD, WT, stimulated with MDP
                                                                                  characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                  GSM1701335

                                                                                  Uncertain

                                                                                  RNA-seq CD WT before MDP, replicate1

                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                  Requirements and decision evidence
                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                      • The required value is not reported.
                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                          • Supported by the indexed evidence.
                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            Source metadata
                                                                                            Source name
                                                                                            Monocytes, CD, WT, unstimulated
                                                                                            Characteristics
                                                                                            cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                            Description
                                                                                            Not reported
                                                                                            Indexed organism evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Indexed assay evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Source
                                                                                            GEO
                                                                                            Original indexed metadata
                                                                                            sample_accession: GSM1701335
                                                                                            sample_title: RNA-seq CD WT before MDP, replicate1
                                                                                            source_name: Monocytes, CD, WT, unstimulated
                                                                                            characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                            GSM1701336

                                                                                            Uncertain

                                                                                            RNA-seq CD WT before MDP, replicate2

                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                            Requirements and decision evidence
                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                  • The required value is not reported.
                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                    • Supported by the indexed evidence.
                                                                                                    • specimen category excludes: Biofluid — Meets requirement
                                                                                                      • Supported by the indexed evidence.
                                                                                                      Source metadata
                                                                                                      Source name
                                                                                                      Monocytes, CD, WT, unstimulated
                                                                                                      Characteristics
                                                                                                      cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                      Description
                                                                                                      Not reported
                                                                                                      Indexed organism evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Indexed assay evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Source
                                                                                                      GEO
                                                                                                      Original indexed metadata
                                                                                                      sample_accession: GSM1701336
                                                                                                      sample_title: RNA-seq CD WT before MDP, replicate2
                                                                                                      source_name: Monocytes, CD, WT, unstimulated
                                                                                                      characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                      GSM1701337

                                                                                                      Uncertain

                                                                                                      RNA-seq healthy control after MDP, replicate1

                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                      Requirements and decision evidence
                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                        • The required value is not reported.
                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • specimen category excludes: Biofluid — Meets requirement
                                                                                                                • Supported by the indexed evidence.
                                                                                                                Source metadata
                                                                                                                Source name
                                                                                                                Monocytes, healthy, WT, stimulated with MDP
                                                                                                                Characteristics
                                                                                                                cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                Description
                                                                                                                Not reported
                                                                                                                Indexed organism evidence
                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                Indexed assay evidence
                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                Source
                                                                                                                GEO
                                                                                                                Original indexed metadata
                                                                                                                sample_accession: GSM1701337
                                                                                                                sample_title: RNA-seq healthy control after MDP, replicate1
                                                                                                                source_name: Monocytes, healthy, WT, stimulated with MDP
                                                                                                                characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                GSM1701338

                                                                                                                Uncertain

                                                                                                                RNA-seq healthy control after MDP, replicate2

                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                Requirements and decision evidence
                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                    • The required value is not reported.
                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                        • Supported by the indexed evidence.
                                                                                                                        • specimen category excludes: Biofluid — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          Source metadata
                                                                                                                          Source name
                                                                                                                          Monocytes, healthy, WT, stimulated with MDP
                                                                                                                          Characteristics
                                                                                                                          cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                          Description
                                                                                                                          Not reported
                                                                                                                          Indexed organism evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Indexed assay evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Source
                                                                                                                          GEO
                                                                                                                          Original indexed metadata
                                                                                                                          sample_accession: GSM1701338
                                                                                                                          sample_title: RNA-seq healthy control after MDP, replicate2
                                                                                                                          source_name: Monocytes, healthy, WT, stimulated with MDP
                                                                                                                          characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                          GSM1701339

                                                                                                                          Uncertain

                                                                                                                          RNA-seq healthy control before MDP, replicate1

                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                          Requirements and decision evidence
                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                • The required value is not reported.
                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                    Source metadata
                                                                                                                                    Source name
                                                                                                                                    Monocytes, healthy, WT, unstimulated
                                                                                                                                    Characteristics
                                                                                                                                    cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                    Description
                                                                                                                                    Not reported
                                                                                                                                    Indexed organism evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Indexed assay evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Source
                                                                                                                                    GEO
                                                                                                                                    Original indexed metadata
                                                                                                                                    sample_accession: GSM1701339
                                                                                                                                    sample_title: RNA-seq healthy control before MDP, replicate1
                                                                                                                                    source_name: Monocytes, healthy, WT, unstimulated
                                                                                                                                    characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                    GSM1701340

                                                                                                                                    Uncertain

                                                                                                                                    RNA-seq healthy control before MDP, replicate2

                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                    Requirements and decision evidence
                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                      • The required value is not reported.
                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                              Source metadata
                                                                                                                                              Source name
                                                                                                                                              Monocytes, healthy, WT, unstimulated
                                                                                                                                              Characteristics
                                                                                                                                              cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                              Description
                                                                                                                                              Not reported
                                                                                                                                              Indexed organism evidence
                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                              Indexed assay evidence
                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                              Source
                                                                                                                                              GEO
                                                                                                                                              Original indexed metadata
                                                                                                                                              sample_accession: GSM1701340
                                                                                                                                              sample_title: RNA-seq healthy control before MDP, replicate2
                                                                                                                                              source_name: Monocytes, healthy, WT, unstimulated
                                                                                                                                              characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                              GSM1701341

                                                                                                                                              Uncertain

                                                                                                                                              small RNA-seq CD NOD2 after MDP, replicate1

                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                              Requirements and decision evidence
                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                  • The required value is not reported.
                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                        Source metadata
                                                                                                                                                        Source name
                                                                                                                                                        Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                        Characteristics
                                                                                                                                                        cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                        Description
                                                                                                                                                        Not reported
                                                                                                                                                        Indexed organism evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Indexed assay evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Source
                                                                                                                                                        GEO
                                                                                                                                                        Original indexed metadata
                                                                                                                                                        sample_accession: GSM1701341
                                                                                                                                                        sample_title: small RNA-seq CD NOD2 after MDP, replicate1
                                                                                                                                                        source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                        characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                        GSM1701342

                                                                                                                                                        Uncertain

                                                                                                                                                        small RNA-seq CD NOD2 after MDP, replicate2

                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                              • The required value is not reported.
                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                  Source metadata
                                                                                                                                                                  Source name
                                                                                                                                                                  Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                                  Characteristics
                                                                                                                                                                  cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                  Description
                                                                                                                                                                  Not reported
                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                  Source
                                                                                                                                                                  GEO
                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                  sample_accession: GSM1701342
                                                                                                                                                                  sample_title: small RNA-seq CD NOD2 after MDP, replicate2
                                                                                                                                                                  source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                                  characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                  GSM1701343

                                                                                                                                                                  Uncertain

                                                                                                                                                                  small RNA-seq CD NOD2 after MDP, replicate3

                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                            Source metadata
                                                                                                                                                                            Source name
                                                                                                                                                                            Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                                            Characteristics
                                                                                                                                                                            cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                            Description
                                                                                                                                                                            Not reported
                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Source
                                                                                                                                                                            GEO
                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                            sample_accession: GSM1701343
                                                                                                                                                                            sample_title: small RNA-seq CD NOD2 after MDP, replicate3
                                                                                                                                                                            source_name: Monocytes, CD, NOD2 SNP, stimulated with MDP
                                                                                                                                                                            characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                            GSM1701344

                                                                                                                                                                            Uncertain

                                                                                                                                                                            small RNA-seq CD NOD2 before MDP, replicate1

                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                    • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                      Source metadata
                                                                                                                                                                                      Source name
                                                                                                                                                                                      Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                      Characteristics
                                                                                                                                                                                      cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                      Description
                                                                                                                                                                                      Not reported
                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Source
                                                                                                                                                                                      GEO
                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                      sample_accession: GSM1701344
                                                                                                                                                                                      sample_title: small RNA-seq CD NOD2 before MDP, replicate1
                                                                                                                                                                                      source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                      characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HOM SNP13 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                      GSM1701345

                                                                                                                                                                                      Uncertain

                                                                                                                                                                                      small RNA-seq CD NOD2 before MDP, replicate2

                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                              • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                Source name
                                                                                                                                                                                                Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                Description
                                                                                                                                                                                                Not reported
                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                Source
                                                                                                                                                                                                GEO
                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                sample_accession: GSM1701345
                                                                                                                                                                                                sample_title: small RNA-seq CD NOD2 before MDP, replicate2
                                                                                                                                                                                                source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                                characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP12 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                GSM1701346

                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                small RNA-seq CD NOD2 before MDP, replicate3

                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                        • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                          Source name
                                                                                                                                                                                                          Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                          cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                          Description
                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Source
                                                                                                                                                                                                          GEO
                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                          sample_accession: GSM1701346
                                                                                                                                                                                                          sample_title: small RNA-seq CD NOD2 before MDP, replicate3
                                                                                                                                                                                                          source_name: Monocytes, CD, NOD2 SNP, unstimulated
                                                                                                                                                                                                          characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: HET SNP13/HET SNP8 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                          GSM1701347

                                                                                                                                                                                                          Uncertain

                                                                                                                                                                                                          small RNA-seq CD WT after MDP, replicate1

                                                                                                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                    Monocytes, CD, WT, stimulated with MDP
                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                    cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                    sample_accession: GSM1701347
                                                                                                                                                                                                                    sample_title: small RNA-seq CD WT after MDP, replicate1
                                                                                                                                                                                                                    source_name: Monocytes, CD, WT, stimulated with MDP
                                                                                                                                                                                                                    characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                                                                    GSM1701348

                                                                                                                                                                                                                    Uncertain

                                                                                                                                                                                                                    small RNA-seq CD WT after MDP, replicate2

                                                                                                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                              Monocytes, CD, WT, stimulated with MDP
                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                              cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                              sample_accession: GSM1701348
                                                                                                                                                                                                                              sample_title: small RNA-seq CD WT after MDP, replicate2
                                                                                                                                                                                                                              source_name: Monocytes, CD, WT, stimulated with MDP
                                                                                                                                                                                                                              characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                                                                              GSM1701349

                                                                                                                                                                                                                              Uncertain

                                                                                                                                                                                                                              small RNA-seq CD WT before MDP, replicate1

                                                                                                                                                                                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                        Monocytes, CD, WT, unstimulated
                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                        cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                        sample_accession: GSM1701349
                                                                                                                                                                                                                                        sample_title: small RNA-seq CD WT before MDP, replicate1
                                                                                                                                                                                                                                        source_name: Monocytes, CD, WT, unstimulated
                                                                                                                                                                                                                                        characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                                                        GSM1701350

                                                                                                                                                                                                                                        Uncertain

                                                                                                                                                                                                                                        small RNA-seq CD WT before MDP, replicate2

                                                                                                                                                                                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                  Monocytes, CD, WT, unstimulated
                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                  cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                  sample_accession: GSM1701350
                                                                                                                                                                                                                                                  sample_title: small RNA-seq CD WT before MDP, replicate2
                                                                                                                                                                                                                                                  source_name: Monocytes, CD, WT, unstimulated
                                                                                                                                                                                                                                                  characteristics: cell type: monocytes; disease status: Crohn's disease; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                                                                  GSM1701351

                                                                                                                                                                                                                                                  Uncertain

                                                                                                                                                                                                                                                  small RNA-seq ctrl_after MDP, replicate1

                                                                                                                                                                                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                            Monocytes, healthy, WT, stimulated with MDP
                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                            cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                            sample_accession: GSM1701351
                                                                                                                                                                                                                                                            sample_title: small RNA-seq ctrl_after MDP, replicate1
                                                                                                                                                                                                                                                            source_name: Monocytes, healthy, WT, stimulated with MDP
                                                                                                                                                                                                                                                            characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                                                                                                            GSM1701352

                                                                                                                                                                                                                                                            Uncertain

                                                                                                                                                                                                                                                            small RNA-seq ctrl_after MDP, replicate2

                                                                                                                                                                                                                                                            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                      Monocytes, healthy, WT, stimulated with MDP
                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                      cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)
                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                      sample_accession: GSM1701352
                                                                                                                                                                                                                                                                      sample_title: small RNA-seq ctrl_after MDP, replicate2
                                                                                                                                                                                                                                                                      source_name: Monocytes, healthy, WT, stimulated with MDP
                                                                                                                                                                                                                                                                      characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: stimulated with muramyl dipeptide (MDP)

                                                                                                                                                                                                                                                                      GSM1701353

                                                                                                                                                                                                                                                                      Uncertain

                                                                                                                                                                                                                                                                      small RNA-seq ctrl_before MDP, replicate1

                                                                                                                                                                                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                Monocytes, healthy, WT, unstimulated
                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                sample_accession: GSM1701353
                                                                                                                                                                                                                                                                                sample_title: small RNA-seq ctrl_before MDP, replicate1
                                                                                                                                                                                                                                                                                source_name: Monocytes, healthy, WT, unstimulated
                                                                                                                                                                                                                                                                                characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                                                                                                GSM1701354

                                                                                                                                                                                                                                                                                Uncertain

                                                                                                                                                                                                                                                                                small RNA-seq ctrl_before MDP, replicate2

                                                                                                                                                                                                                                                                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                          Monocytes, healthy, WT, unstimulated
                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                          cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated
                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                          sample_accession: GSM1701354
                                                                                                                                                                                                                                                                                          sample_title: small RNA-seq ctrl_before MDP, replicate2
                                                                                                                                                                                                                                                                                          source_name: Monocytes, healthy, WT, unstimulated
                                                                                                                                                                                                                                                                                          characteristics: cell type: monocytes; disease status: healthy; genotype: WT NOD2 + WT ATG16L1; treatment: unstimulated

                                                                                                                                                                                                                                                                                          Excluded samples (0)

                                                                                                                                                                                                                                                                                          No excluded samples.