Matching samples

GSE83381 · Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq]

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

10 case / 0 control samples elsewhere in the study have incomplete or conflicting evidence; they are not included above

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (12)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

GSM2200449

Uncertain

CD T/T rep1

Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Insufficient evidence
        • The required value is not reported.
        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
          • Supported by the indexed evidence.
          • specimen category excludes: Biofluid — Meets requirement
            • Supported by the indexed evidence.
            Source metadata
            Source name
            Peripheral blood derived mononuclear cells
            Characteristics
            disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753
            Description
            Not reported
            Indexed organism evidence
            INFERRED · PARENT_INHERITED: Not reported
            Indexed assay evidence
            INFERRED · PARENT_INHERITED: Not reported
            Source
            GEO
            Original indexed metadata
            sample_accession: GSM2200449
sample_title: CD T/T rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753

            GSM2200450

            Uncertain

            CD C/C rep1

            Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

            Requirements and decision evidence
            • organism: Homo sapiens — Insufficient evidence
              • The required value is not reported.
              • assay type: bulk RNA-seq — Insufficient evidence
                • The required value is not reported.
                • specimen category: Tissue or biopsy — Insufficient evidence
                  • The required value is not reported.
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Meets requirement
                      • Supported by the indexed evidence.
                      Source metadata
                      Source name
                      Peripheral blood derived mononuclear cells
                      Characteristics
                      disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                      Description
                      Not reported
                      Indexed organism evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Indexed assay evidence
                      INFERRED · PARENT_INHERITED: Not reported
                      Source
                      GEO
                      Original indexed metadata
                      sample_accession: GSM2200450
sample_title: CD C/C rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                      GSM2200451

                      Uncertain

                      CD T/T rep2

                      Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                      Requirements and decision evidence
                      • organism: Homo sapiens — Insufficient evidence
                        • The required value is not reported.
                        • assay type: bulk RNA-seq — Insufficient evidence
                          • The required value is not reported.
                          • specimen category: Tissue or biopsy — Insufficient evidence
                            • The required value is not reported.
                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                              • Supported by the indexed evidence.
                              • specimen category excludes: Biofluid — Meets requirement
                                • Supported by the indexed evidence.
                                Source metadata
                                Source name
                                Peripheral blood derived mononuclear cells
                                Characteristics
                                disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753
                                Description
                                Not reported
                                Indexed organism evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Indexed assay evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Source
                                GEO
                                Original indexed metadata
                                sample_accession: GSM2200451
sample_title: CD T/T rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753

                                GSM2200452

                                Uncertain

                                CD C/C rep2

                                Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                Requirements and decision evidence
                                • organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • specimen category: Tissue or biopsy — Insufficient evidence
                                      • The required value is not reported.
                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                        • Supported by the indexed evidence.
                                        • specimen category excludes: Biofluid — Meets requirement
                                          • Supported by the indexed evidence.
                                          Source metadata
                                          Source name
                                          Peripheral blood derived mononuclear cells
                                          Characteristics
                                          disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                          Description
                                          Not reported
                                          Indexed organism evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Indexed assay evidence
                                          INFERRED · PARENT_INHERITED: Not reported
                                          Source
                                          GEO
                                          Original indexed metadata
                                          sample_accession: GSM2200452
sample_title: CD C/C rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                          GSM2200453

                                          Uncertain

                                          CD T/T LPS+ rep1

                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                          Requirements and decision evidence
                                          • organism: Homo sapiens — Insufficient evidence
                                            • The required value is not reported.
                                            • assay type: bulk RNA-seq — Insufficient evidence
                                              • The required value is not reported.
                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                • The required value is not reported.
                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • specimen category excludes: Biofluid — Meets requirement
                                                    • Supported by the indexed evidence.
                                                    Source metadata
                                                    Source name
                                                    Peripheral blood derived mononuclear cells
                                                    Characteristics
                                                    disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753
                                                    Description
                                                    Not reported
                                                    Indexed organism evidence
                                                    INFERRED · PARENT_INHERITED: Not reported
                                                    Indexed assay evidence
                                                    INFERRED · PARENT_INHERITED: Not reported
                                                    Source
                                                    GEO
                                                    Original indexed metadata
                                                    sample_accession: GSM2200453
sample_title: CD T/T LPS+ rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753

                                                    GSM2200454

                                                    Uncertain

                                                    CD C/C LPS+ rep1

                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                    Requirements and decision evidence
                                                    • organism: Homo sapiens — Insufficient evidence
                                                      • The required value is not reported.
                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                        • The required value is not reported.
                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                          • The required value is not reported.
                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                            • Supported by the indexed evidence.
                                                            • specimen category excludes: Biofluid — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              Source metadata
                                                              Source name
                                                              Peripheral blood derived mononuclear cells
                                                              Characteristics
                                                              disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM2200454
sample_title: CD C/C LPS+ rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                              GSM2200455

                                                              Uncertain

                                                              CD T/T LPS+ rep2

                                                              Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                              Requirements and decision evidence
                                                              • organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • specimen category: Tissue or biopsy — Insufficient evidence
                                                                    • The required value is not reported.
                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                      • Supported by the indexed evidence.
                                                                      • specimen category excludes: Biofluid — Meets requirement
                                                                        • Supported by the indexed evidence.
                                                                        Source metadata
                                                                        Source name
                                                                        Peripheral blood derived mononuclear cells
                                                                        Characteristics
                                                                        disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753
                                                                        Description
                                                                        Not reported
                                                                        Indexed organism evidence
                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                        Indexed assay evidence
                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                        Source
                                                                        GEO
                                                                        Original indexed metadata
                                                                        sample_accession: GSM2200455
sample_title: CD T/T LPS+ rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: T/T rs6716753

                                                                        GSM2200456

                                                                        Uncertain

                                                                        CD C/C LPS+ rep2

                                                                        Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Case marker detected.

                                                                        Requirements and decision evidence
                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                          • The required value is not reported.
                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • specimen category: Tissue or biopsy — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • specimen category excludes: Biofluid — Meets requirement
                                                                                  • Supported by the indexed evidence.
                                                                                  Source metadata
                                                                                  Source name
                                                                                  Peripheral blood derived mononuclear cells
                                                                                  Characteristics
                                                                                  disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                                                  Description
                                                                                  Not reported
                                                                                  Indexed organism evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Indexed assay evidence
                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                  Source
                                                                                  GEO
                                                                                  Original indexed metadata
                                                                                  sample_accession: GSM2200456
sample_title: CD C/C LPS+ rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: Crohn's disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                                                  GSM2200457

                                                                                  Uncertain

                                                                                  WT C/C rep1

                                                                                  Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                  Requirements and decision evidence
                                                                                  • Case: organism: Homo sapiens — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                      • The required value is not reported.
                                                                                      • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                          • Supported by the indexed evidence.
                                                                                          • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            • Control: organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                  • The required value is not reported.
                                                                                                  • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                    • Supported by the indexed evidence.
                                                                                                    • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                      • Supported by the indexed evidence.
                                                                                                      Source metadata
                                                                                                      Source name
                                                                                                      Peripheral blood derived mononuclear cells
                                                                                                      Characteristics
                                                                                                      disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                                                                      Description
                                                                                                      Not reported
                                                                                                      Indexed organism evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Indexed assay evidence
                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                      Source
                                                                                                      GEO
                                                                                                      Original indexed metadata
                                                                                                      sample_accession: GSM2200457
sample_title: WT C/C rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                                                                      GSM2200458

                                                                                                      Uncertain

                                                                                                      WT C/C rep2

                                                                                                      Not included: the study role or selected requirements have incomplete or conflicting evidence. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Insufficient evidence. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Insufficient evidence. Study role: No explicit case or control marker detected.

                                                                                                      Requirements and decision evidence
                                                                                                      • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                        • The required value is not reported.
                                                                                                        • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • Case: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • Case: specimen category excludes: Biofluid — Meets requirement
                                                                                                                • Supported by the indexed evidence.
                                                                                                                • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                    • The required value is not reported.
                                                                                                                    • Control: specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                        • Supported by the indexed evidence.
                                                                                                                        • Control: specimen category excludes: Biofluid — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          Source metadata
                                                                                                                          Source name
                                                                                                                          Peripheral blood derived mononuclear cells
                                                                                                                          Characteristics
                                                                                                                          disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                                                                                          Description
                                                                                                                          Not reported
                                                                                                                          Indexed organism evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Indexed assay evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Source
                                                                                                                          GEO
                                                                                                                          Original indexed metadata
                                                                                                                          sample_accession: GSM2200458
sample_title: WT C/C rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                                                                                          GSM2200459

                                                                                                                          Uncertain

                                                                                                                          WT C/C LPS rep1

                                                                                                                          Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                          Requirements and decision evidence
                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                • The required value is not reported.
                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                  • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                    Source metadata
                                                                                                                                    Source name
                                                                                                                                    Peripheral blood derived mononuclear cells
                                                                                                                                    Characteristics
                                                                                                                                    disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                                                                                                    Description
                                                                                                                                    Not reported
                                                                                                                                    Indexed organism evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Indexed assay evidence
                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                    Source
                                                                                                                                    GEO
                                                                                                                                    Original indexed metadata
                                                                                                                                    sample_accession: GSM2200459
sample_title: WT C/C LPS rep1
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                                                                                                    GSM2200460

                                                                                                                                    Uncertain

                                                                                                                                    WT C/C LPS rep2

                                                                                                                                    Not included: the study role or selected requirements have incomplete or conflicting evidence. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Insufficient evidence. Study role: Treatment case marker detected.

                                                                                                                                    Requirements and decision evidence
                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                      • The required value is not reported.
                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • specimen category: Tissue or biopsy — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • specimen category excludes: Biofluid — Meets requirement
                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                              Source metadata
                                                                                                                                              Source name
                                                                                                                                              Peripheral blood derived mononuclear cells
                                                                                                                                              Characteristics
                                                                                                                                              disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753
                                                                                                                                              Description
                                                                                                                                              Not reported
                                                                                                                                              Indexed organism evidence
                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                              Indexed assay evidence
                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                              Source
                                                                                                                                              GEO
                                                                                                                                              Original indexed metadata
                                                                                                                                              sample_accession: GSM2200460
sample_title: WT C/C LPS rep2
source_name: Peripheral blood derived mononuclear cells
characteristics: disease state: non-disease; cell type: Peripheral blood derived mononuclear cells; genotype: C/C rs6716753

                                                                                                                                              Excluded samples (8)

                                                                                                                                              GSM2344751

                                                                                                                                              Excluded

                                                                                                                                              Donor 1 control 0h

                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                              Requirements and decision evidence
                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                  • The required value is not reported.
                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                    • Donor 1 control 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                      • Donor 1 control 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                    Source metadata
                                                                                                                                                    Source name
                                                                                                                                                    Peripheral blood
                                                                                                                                                    Characteristics
                                                                                                                                                    disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                    Description
                                                                                                                                                    Not reported
                                                                                                                                                    Indexed organism evidence
                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                    Indexed assay evidence
                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                    Source
                                                                                                                                                    GEO
                                                                                                                                                    Original indexed metadata
                                                                                                                                                    sample_accession: GSM2344751
sample_title: Donor 1 control 0h
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: none

                                                                                                                                                    GSM2344752

                                                                                                                                                    Excluded

                                                                                                                                                    Donor 1 SP140 KD 0h

                                                                                                                                                    Excluded: at least one selected requirement is not met. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Does not meet requirement. Case: specimen category excludes: Biofluid — Does not meet requirement. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Does not meet requirement. Control: specimen category excludes: Biofluid — Does not meet requirement. Study role: No explicit case or control marker detected.

                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                    • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                      • The required value is not reported.
                                                                                                                                                      • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                        • The required value is not reported.
                                                                                                                                                        • Case: specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                          • Donor 1 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                        • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                          • Case: specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                            • Donor 1 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                          • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                              • The required value is not reported.
                                                                                                                                                              • Control: specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                • Donor 1 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                              • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                • Control: specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                  • Donor 1 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                Source metadata
                                                                                                                                                                Source name
                                                                                                                                                                Peripheral blood
                                                                                                                                                                Characteristics
                                                                                                                                                                disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                Description
                                                                                                                                                                Not reported
                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                Source
                                                                                                                                                                GEO
                                                                                                                                                                Original indexed metadata
                                                                                                                                                                sample_accession: GSM2344752
sample_title: Donor 1 SP140 KD 0h
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140

                                                                                                                                                                GSM2344753

                                                                                                                                                                Excluded

                                                                                                                                                                Donor 1 control 4h LPS

                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                      • Donor 1 control 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                        • Donor 1 control 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                      Source metadata
                                                                                                                                                                      Source name
                                                                                                                                                                      Peripheral blood
                                                                                                                                                                      Characteristics
                                                                                                                                                                      disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                      Description
                                                                                                                                                                      Not reported
                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                      Source
                                                                                                                                                                      GEO
                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                      sample_accession: GSM2344753
sample_title: Donor 1 control 4h LPS
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: none

                                                                                                                                                                      GSM2344754

                                                                                                                                                                      Excluded

                                                                                                                                                                      Donor 1 SP140 KD 4h LPS

                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment case marker detected.

                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                            • Donor 1 SP140 KD 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                              • Donor 1 SP140 KD 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                            Source metadata
                                                                                                                                                                            Source name
                                                                                                                                                                            Peripheral blood
                                                                                                                                                                            Characteristics
                                                                                                                                                                            disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                            Description
                                                                                                                                                                            Not reported
                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                            Source
                                                                                                                                                                            GEO
                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                            sample_accession: GSM2344754
sample_title: Donor 1 SP140 KD 4h LPS
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140

                                                                                                                                                                            GSM2344755

                                                                                                                                                                            Excluded

                                                                                                                                                                            Donor 2 control 0h

                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                  • Donor 2 control 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                    • Donor 2 control 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                  Source metadata
                                                                                                                                                                                  Source name
                                                                                                                                                                                  Peripheral blood
                                                                                                                                                                                  Characteristics
                                                                                                                                                                                  disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                  Description
                                                                                                                                                                                  Not reported
                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                  Source
                                                                                                                                                                                  GEO
                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                  sample_accession: GSM2344755
sample_title: Donor 2 control 0h
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: none

                                                                                                                                                                                  GSM2344756

                                                                                                                                                                                  Excluded

                                                                                                                                                                                  Donor 2 SP140 KD 0h

                                                                                                                                                                                  Excluded: at least one selected requirement is not met. Case: organism: Homo sapiens — Insufficient evidence. Case: assay type: bulk RNA-seq — Insufficient evidence. Case: specimen category: Tissue or biopsy — Does not meet requirement. Case: specimen category excludes: Biofluid — Does not meet requirement. Control: organism: Homo sapiens — Insufficient evidence. Control: assay type: bulk RNA-seq — Insufficient evidence. Control: specimen category: Tissue or biopsy — Does not meet requirement. Control: specimen category excludes: Biofluid — Does not meet requirement. Study role: No explicit case or control marker detected.

                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                  • Case: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                    • Case: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                      • Case: specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                        • Donor 2 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                      • Case: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                        • Case: specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                          • Donor 2 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                        • Control: organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • Control: assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                            • Control: specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                              • Donor 2 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                            • Control: excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                              • Control: specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                • Donor 2 SP140 KD 0h Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                              Source metadata
                                                                                                                                                                                              Source name
                                                                                                                                                                                              Peripheral blood
                                                                                                                                                                                              Characteristics
                                                                                                                                                                                              disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                              Description
                                                                                                                                                                                              Not reported
                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                              Source
                                                                                                                                                                                              GEO
                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                              sample_accession: GSM2344756
sample_title: Donor 2 SP140 KD 0h
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140

                                                                                                                                                                                              GSM2344757

                                                                                                                                                                                              Excluded

                                                                                                                                                                                              Donor 2 control 4h LPS

                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                    • Donor 2 control 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                      • Donor 2 control 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                    Source name
                                                                                                                                                                                                    Peripheral blood
                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                    disease status: unknown; cell type: PBMC derived macrophage; sirna: none
                                                                                                                                                                                                    Description
                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                    Source
                                                                                                                                                                                                    GEO
                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                    sample_accession: GSM2344757
sample_title: Donor 2 control 4h LPS
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: none

                                                                                                                                                                                                    GSM2344758

                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                    Donor 2 SP140 KD 4h LPS

                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment case marker detected.

                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                          • Donor 2 SP140 KD 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                            • Donor 2 SP140 KD 4h LPS Peripheral blood disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                          Source name
                                                                                                                                                                                                          Peripheral blood
                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                          disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140
                                                                                                                                                                                                          Description
                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                          Source
                                                                                                                                                                                                          GEO
                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                          sample_accession: GSM2344758
sample_title: Donor 2 SP140 KD 4h LPS
source_name: Peripheral blood
characteristics: disease status: unknown; cell type: PBMC derived macrophage; sirna: SP140