GSE84044

Characterization of gene expression profile in HBV-related liver fibrosis patients

Whole-study status Not suitable

Dataset does not meet the current suitability threshold.

Whole-study downloads — these do not apply your sample requirements.

Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

View matching samples

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

Summary

Hepatitis B virus (HBV) infection is a leading risk factor for liver fibrosis (LF) and hepatocellular carcinoma. Emerging evidence indicates that host genetic, virological and immunological factors will influence the fibrotic progress. Many previous studies have focused on specific pathways or genes included in LF mechanism, however global view of the whole genome expresion profile in HBV related LF patients never been studied, and the mechanisms underlying the promotion of liver fibrosis progression remain obscure. Here we collected liver biopsy samples from 124 chronic hepatitis B (CHB) patients and used Affymetrix HG U133 Plus 2.0 microarray to quantify the transcriptome of these patients. Through integrated data analysis, including geneset enrichment analysis (GSEA), weighted gene co-expression analysis (WGCNA), differential expressed gene (DEG) screening, trend test, principle component analysis (PCA) etc., we identified several key pathways and hub genes participated in the initiation and exacerbation of liver fibrotic progress. The function of these hub genes were also validated by in vitro and in vivo experiments using HepG2, Huh7 and LX-2 cell lines and transgenic mice. This is the first large-scale study investigating the gene expression profile in HBV-related LF patients which will be crucial for unlocking the gene functions and gene-gene correlations in fibrosis progess.

Overall design

Liver biopy samples from 124 CHB patients were collected. The pathological Scheuer Score of each sample were evaluated base on the inflamation and fibrosis severity. Gene expresson of samples in different stage were compared and analyzed.

Source Evidence

4 sources
Source Contribution Status
GEO

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Sample records
124 GSM samples
Primary source
recount3

Planned trusted source for processed count availability.

No match found
Expression Atlas

Planned source for curated expression experiment links.

No match found
PubMed

Primary GEO citations and related PubMed articles that mention this dataset.

21 linked publications 21 DOIs

Primary publication

  1. Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis. Scientific reports, 2017

Related publications

  1. Serum ribonucleotide reductase M2 is a potential biomarker for diagnosing and monitoring liver fibrosis in chronic hepatitis B patients. Journal of medical virology, 2023
  2. Rutaecarpine alleviates liver fibrosis by modulating the TRPV1/Connexin 43 axis: A study based on transcriptome data, single-cell sequencing data, and cell experiments. Biochemical and biophysical research communications, 2025
  3. Evaluating the role of IER3+ macrophages in the prognosis of liver fibrosis by bulk and single-cell transcriptional analyses. iLIVER, 2024
  4. RAB25 promotes hepatitis B virus-induced liver fibrosis progression through activation of the PI3K/AKT signaling pathway. Virus research, 2026
  5. Integrated analyses reveal CST7 and DUSP5 regulate Th2 cells differentiation to promote chronic HBV infection. Genes and immunity, 2024
  6. Identifying SUMOylation-related genes in liver fibrosis with bioinformatics and experimental models for diagnostic insights. Scientific reports, 2025
  7. Accelerators of chronic hepatitis B fibrosis cirrhosis CCND1 gene expression and promoter hypomethylation. Scientific reports, 2025
  8. Uncovering potentially targetable genes in liver fibrosis via bioinformatics and experimental validation. Scientific reports, 2026
  9. Exploration of PDHA1-related prognostic genes in liver fibrosis. Medicine, 2025
  10. Comprehensive Analysis of m7G-Related Genes and Chronic Hepatitis B: Diagnostic Markers, Immune Microenvironment Regulation, Disease Progression. Journal of immunology research, 2023
  11. Identification of Key Targets of Herbal Compounds for Liver Fibrosis Using Network Pharmacology Combined With Transcriptomics. Gastroenterology research and practice, 2026
  12. Identification of functional genes in liver fibrosis based on bioinformatics analysis of a lncRNA-mediated ceRNA network. BMC medical genomics, 2024
  13. Neutrophil extracellular trapping network-associated biomarkers in liver fibrosis: machine learning and experimental validation. Journal of translational medicine, 2025
  14. HBV activates hepatic stellate cells through RUNX2/ITGBL1 axis. Virology journal, 2025
  15. Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling. Iranian journal of basic medical sciences, 2026
  16. Machine learning and experimental validation identified autophagy signature in hepatic fibrosis. Frontiers in immunology, 2024
  17. Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation. Frontiers in immunology, 2025
  18. Identification of CCND1 and IL7R as core JAK-STAT pathway genes promoting hepatitis B-related liver fibrosis. Frontiers in immunology, 2026
  19. Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks. Frontiers in molecular biosciences, 2023
  20. From a Multi-Omics Signature to a Therapeutic Candidate: Computational Prediction and Experimental Validation in Liver Fibrosis. Pharmaceuticals (Basel, Switzerland), 2026
Available

Metadata Quality Components

Analysis Readiness

Not ready
33% DE readiness

Contrast completeness

0/25 pts

No usable case/control contrast was detected.

Minimum group size

0/20 pts

Minimum group size cannot be evaluated until a complete contrast exists.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

3/15 pts

Unassigned or review-needed samples remain before analysis.

Blocking warnings

0/10 pts

Critical warnings must be resolved before downstream analysis.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

  • No complete case/control contrast is available.
  • 124 samples are still unassigned.
  • Critical dataset warnings must be resolved.

Next Steps

  • Resolve unassigned or review-needed samples in the grouping table.
  • Resolve critical warnings before downstream analysis.

Analysis Preparation Checklist

3/6 ready

Group labels reviewed

Blocked

No complete case/control grouping exists yet.

Review the sample grouping table and assign both case and control groups.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Needs review

0 review-needed samples and 124 unassigned samples remain.

Resolve ambiguous and unassigned samples before finalizing the contrast.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source traceability preserved

Ready

The dataset and sample accessions can be traced back to GEO.

Keep GEO accessions with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

Analysis readiness has blockers that must be resolved before DE.

Analysis preparation checklist contains blocked items.

No complete case/control or treatment/control contrast is available.

At least one comparison group has fewer than two samples.

One or more samples are unassigned and need manual grouping decisions.

Critical dataset warnings are present.

Assay context may require expert handling before DESeq2-style analysis.

Study design is model-system or unclear and should be reviewed before analysis.

Why This Is Ranked Here

Tumor vs normal
Not suitable Dataset does not meet the current suitability threshold.

Applied Review Decisions

No active review decisions affect this ranking.

Derived Classifications

  • Assay differs from search intent Microarray Search intent expects bulk RNA-seq. Assay came from Normalization rules.
  • Disease context Fibrosis, hepatocellular carcinoma, liver fibrosis Disease context came from Normalization rules.
  • Likely case group No case group detected 0 samples
  • Likely control group No control group detected 0 samples

Intent Interpretation

  • Downgrade or exclusion reason Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%. Derived from current-intent ranking reasons.

Ranking Facts

Supporting evidence

  • Interpreted disease metadata: Fibrosis, Hepatocellular carcinoma, Infectious disease or host response, Liver fibrosis.
  • Processed data is available for downstream review.
  • External evidence: PubMed links 21 publications; 21 DOIs available: PMID 28262670, PMID 37206976, PMID 37808522, PMID 37814947, PMID 38378545.
  • Publication context: Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis.. Scientific reports, 2017. PMID 28262670. DOI 10.1038/srep43446.
  • Publication context: Comprehensive Analysis of m7G-Related Genes and Chronic Hepatitis B: Diagnostic Markers, Immune Microenvironment Regulation, Disease Progression.. Journal of immunology research, 2023. PMID 37206976. DOI 10.1155/2023/9471520.
  • Publication context: Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks.. Frontiers in molecular biosciences, 2023. PMID 37808522. DOI 10.3389/fmolb.2023.1275897.
  • Publication context: 18 additional linked PubMed publications are available.

Cautions

  • Comparison: Unclear study design. Specimen: Tissue. Comparison suitability: 0%.
  • Downgraded for tissue search because study design or specimen source is unclear.
  • Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
  • Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
  • Missing or unclear metadata. Unclear study design downgraded for patient tissue tumor-vs-normal search intent.
  • Microarray expression context downgraded below primary bulk RNA-seq for the default tissue ranking.
  • Missing or unclear metadata. Group clarity - Case and control groups are not clear from sample metadata.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Overall score capped because microarray cohorts should be compared separately from RNA-seq cohorts.
  • Missing or unclear metadata. Comparison - Unclear study design. Specimen - Tissue. Comparison suitability: 0%.
  • Missing or unclear metadata. Downgraded for tissue search because study design or specimen source is unclear.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Dataset Warnings

Normalized Fields

254 fields

Sample Group Preview

showing 50 of 124 preview rows
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Study totals: Case 0 | Control 0 | Unassigned 124 | Excluded 0 | Ambiguous 0 showing 50 of 124 preview rows
Group Role Accession Title Source / characteristics Reason
Unassigned Unassigned GSM2226280 Patient 0001, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0001 Tissue: Hepatic tissue; Gender: Male; Age: 42; Batch: 1; Scheuer score g: 0; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226281 Patient 0002, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0002 Tissue: Hepatic tissue; Gender: Male; Age: 56; Batch: 1; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226282 Patient 0003, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0003 Tissue: Hepatic tissue; Gender: Female; Age: 54; Batch: 1; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226283 Patient 0004, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0004 Tissue: Hepatic tissue; Gender: Female; Age: 41; Batch: 3; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226284 Patient 0005, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0005 Tissue: Hepatic tissue; Gender: Female; Age: 37; Batch: 1; Scheuer score g: 2; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226285 Patient 0006, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0006 Tissue: Hepatic tissue; Gender: Female; Age: 33; Batch: 1; Scheuer score g: 1; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226286 Patient 0007, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0007 Tissue: Hepatic tissue; Gender: Male; Age: 52; Batch: 1; Scheuer score g: 1; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226287 Patient 0008, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0008 Tissue: Hepatic tissue; Gender: Male; Age: 35; Batch: 1; Scheuer score g: 1; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226288 Patient 0009, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0009 Tissue: Hepatic tissue; Gender: Male; Age: 43; Batch: 1; Scheuer score g: 0; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226289 Patient 0010, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0010 Tissue: Hepatic tissue; Gender: Male; Age: 44; Batch: 1; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226290 Patient 0011, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0011 Tissue: Hepatic tissue; Gender: Female; Age: 35; Batch: 1; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226291 Patient 0012, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0012 Tissue: Hepatic tissue; Gender: Male; Age: 58; Batch: 1; Scheuer score g: 1; Scheuer score s: 1 No explicit case or control marker detected.
Unassigned Unassigned GSM2226292 Patient 0013, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0013 Tissue: Hepatic tissue; Gender: Male; Age: 43; Batch: 1; Scheuer score g: 3; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226293 Patient 0014, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0014 Tissue: Hepatic tissue; Gender: Male; Age: 34; Batch: 1; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226294 Patient 0015, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0015 Tissue: Hepatic tissue; Gender: Male; Age: 34; Batch: 1; Scheuer score g: 2; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226295 Patient 0016, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0016 Tissue: Hepatic tissue; Gender: Male; Age: 58; Batch: 4; Scheuer score g: 2; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226296 Patient 0017, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0017 Tissue: Hepatic tissue; Gender: Male; Age: 48; Batch: 3; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226297 Patient 0018, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0018 Tissue: Hepatic tissue; Gender: Female; Age: 48; Batch: 3; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226298 Patient 0019, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0019 Tissue: Hepatic tissue; Gender: Female; Age: 33; Batch: 3; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226299 Patient 0020, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0020 Tissue: Hepatic tissue; Gender: Male; Age: 37; Batch: 3; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226300 Patient 0021, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0021 Tissue: Hepatic tissue; Gender: Male; Age: 59; Batch: 4; Scheuer score g: 4; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226301 Patient 0022, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0022 Tissue: Hepatic tissue; Gender: Female; Age: 37; Batch: 3; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226302 Patient 0023, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0023 Tissue: Hepatic tissue; Gender: Female; Age: 64; Batch: 3; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226303 Patient 0024, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0024 Tissue: Hepatic tissue; Gender: Female; Age: 37; Batch: 3; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226304 Patient 0025, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0025 Tissue: Hepatic tissue; Gender: Male; Age: 45; Batch: 4; Scheuer score g: 1; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226305 Patient 0026, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0026 Tissue: Hepatic tissue; Gender: Female; Age: 40; Batch: 4; Scheuer score g: 2; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226306 Patient 0027, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0027 Tissue: Hepatic tissue; Gender: Female; Age: 40; Batch: 4; Scheuer score g: 3; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226307 Patient 0028, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0028 Tissue: Hepatic tissue; Gender: Male; Age: 60; Batch: 1; Scheuer score g: 4; Scheuer score s: 4 No explicit case or control marker detected.
Unassigned Unassigned GSM2226308 Patient 0029, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0029 Tissue: Hepatic tissue; Gender: Female; Age: 61; Batch: 1; Scheuer score g: 1; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226309 Patient 0030, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0030 Tissue: Hepatic tissue; Gender: Male; Age: 29; Batch: 1; Scheuer score g: 2; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226310 Patient 0031, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0031 Tissue: Hepatic tissue; Gender: Male; Age: 44; Batch: 1; Scheuer score g: 0; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226311 Patient 0032, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0032 Tissue: Hepatic tissue; Gender: Male; Age: 46; Batch: 1; Scheuer score g: 2; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226312 Patient 0033, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0033 Tissue: Hepatic tissue; Gender: Male; Age: 32; Batch: 1; Scheuer score g: 4; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226313 Patient 0034, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0034 Tissue: Hepatic tissue; Gender: Male; Age: 33; Batch: 1; Scheuer score g: 2; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226314 Patient 0035, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0035 Tissue: Hepatic tissue; Gender: Male; Age: 28; Batch: 3; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226315 Patient 0036, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0036 Tissue: Hepatic tissue; Gender: Male; Age: 46; Batch: 3; Scheuer score g: 1; Scheuer score s: 1 No explicit case or control marker detected.
Unassigned Unassigned GSM2226316 Patient 0037, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0037 Tissue: Hepatic tissue; Gender: Male; Age: 51; Batch: 1; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226317 Patient 0038, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0038 Tissue: Hepatic tissue; Gender: Male; Age: 47; Batch: 1; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226318 Patient 0039, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0039 Tissue: Hepatic tissue; Gender: Male; Age: 52; Batch: 4; Scheuer score g: 3; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226319 Patient 0040, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0040 Tissue: Hepatic tissue; Gender: Male; Age: 44; Batch: 1; Scheuer score g: 0; Scheuer score s: 1 No explicit case or control marker detected.
Unassigned Unassigned GSM2226320 Patient 0041, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0041 Tissue: Hepatic tissue; Gender: Female; Age: 55; Batch: 4; Scheuer score g: 2; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226321 Patient 0042, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0042 Tissue: Hepatic tissue; Gender: Male; Age: 38; Batch: 1; Scheuer score g: 3; Scheuer score s: 3 No explicit case or control marker detected.
Unassigned Unassigned GSM2226322 Patient 0043, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0043 Tissue: Hepatic tissue; Gender: Female; Age: 56; Batch: 1; Scheuer score g: 2; Scheuer score s: 1 No explicit case or control marker detected.
Unassigned Unassigned GSM2226323 Patient 0044, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0044 Tissue: Hepatic tissue; Gender: Male; Age: 26; Batch: 1; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226324 Patient 0045, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0045 Tissue: Hepatic tissue; Gender: Male; Age: 42; Batch: 1; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226325 Patient 0046, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0046 Tissue: Hepatic tissue; Gender: Female; Age: 39; Batch: 1; Scheuer score g: 0; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226326 Patient 0047, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0047 Tissue: Hepatic tissue; Gender: Female; Age: 71; Batch: 1; Scheuer score g: 2; Scheuer score s: 2 No explicit case or control marker detected.
Unassigned Unassigned GSM2226327 Patient 0048, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0048 Tissue: Hepatic tissue; Gender: Male; Age: 57; Batch: 1; Scheuer score g: 0; Scheuer score s: 0 No explicit case or control marker detected.
Unassigned Unassigned GSM2226328 Patient 0049, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0049 Tissue: Hepatic tissue; Gender: Male; Age: 33; Batch: 1; Scheuer score g: 1; Scheuer score s: 1 No explicit case or control marker detected.
Unassigned Unassigned GSM2226329 Patient 0050, hepatic tissue Hepatic tissue from chronic hepatitis B patients 0050 Tissue: Hepatic tissue; Gender: Male; Age: 60; Batch: 1; Scheuer score g: 3; Scheuer score s: 3 No explicit case or control marker detected.
74 additional unassigned samples are hidden from this preview.

Use as Discovery Cohort

External Validation Finder

Carry Siftome's disease, organism, specimen, assay, data type, and accession into a validation project. Uncertain fields remain Unknown.