Matching samples

GSE94648 · Expression data from peripheral whole blood of non-IBD controls, CD and UC patients

Download matching samples CSV
Selected cohort requirements

Samples meeting selected requirements: 0 cases / 0 controls

Patient pairs verified in indexed sample metadata: 0

A case/control comparison meeting these requirements is not confirmed.

Counts describe samples, not independent patients. Pair verification uses explicit subject identifiers in indexed sample metadata. Zero verified pairs does not establish that the study is unpaired; reported matched-normal design alone is insufficient.

The CSV contains only the confirmed cases and controls below. Excluded and uncertain samples are shown for review and are not exported.

These are sample eligibility decisions from the current indexed metadata. Study-level search filters and minimum sample counts do not establish expression quality or analysis readiness.

Included samples (0)

No samples meet the selected requirements. The CSV contains its column headers only.

Uncertain samples (0)

These samples need more evidence before they can be counted. This includes samples without a confirmed case/control role.

No uncertain samples.

Excluded samples (97)

GSM2480251

Excluded

Active UC_0038S

Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

Requirements and decision evidence
  • organism: Homo sapiens — Insufficient evidence
    • The required value is not reported.
    • assay type: bulk RNA-seq — Insufficient evidence
      • The required value is not reported.
      • specimen category: Tissue or biopsy — Does not meet requirement
        • The reported value differs from the selected requirement.
        • Active UC_0038S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
        • Supported by the indexed evidence.
        • specimen category excludes: Biofluid — Does not meet requirement
          • The reported value differs from the selected requirement.
          • Active UC_0038S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
        Source metadata
        Source name
        Human peripheral whole blood from endoscopically active UC patient
        Characteristics
        subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 8; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
        Description
        Not reported
        Indexed organism evidence
        INFERRED · PARENT_INHERITED: Not reported
        Indexed assay evidence
        INFERRED · PARENT_INHERITED: Not reported
        Source
        GEO
        Original indexed metadata
        sample_accession: GSM2480251
        sample_title: Active UC_0038S
        source_name: Human peripheral whole blood from endoscopically active UC patient
        characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 8; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

        GSM2480252

        Excluded

        Active UC_0078S

        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

        Requirements and decision evidence
        • organism: Homo sapiens — Insufficient evidence
          • The required value is not reported.
          • assay type: bulk RNA-seq — Insufficient evidence
            • The required value is not reported.
            • specimen category: Tissue or biopsy — Does not meet requirement
              • The reported value differs from the selected requirement.
              • Active UC_0078S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
              • Supported by the indexed evidence.
              • specimen category excludes: Biofluid — Does not meet requirement
                • The reported value differs from the selected requirement.
                • Active UC_0078S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
              Source metadata
              Source name
              Human peripheral whole blood from endoscopically active UC patient
              Characteristics
              subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0.5; age (years): 42; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
              Description
              Not reported
              Indexed organism evidence
              INFERRED · PARENT_INHERITED: Not reported
              Indexed assay evidence
              INFERRED · PARENT_INHERITED: Not reported
              Source
              GEO
              Original indexed metadata
              sample_accession: GSM2480252
              sample_title: Active UC_0078S
              source_name: Human peripheral whole blood from endoscopically active UC patient
              characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0.5; age (years): 42; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

              GSM2480253

              Excluded

              Active UC_0083S

              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

              Requirements and decision evidence
              • organism: Homo sapiens — Insufficient evidence
                • The required value is not reported.
                • assay type: bulk RNA-seq — Insufficient evidence
                  • The required value is not reported.
                  • specimen category: Tissue or biopsy — Does not meet requirement
                    • The reported value differs from the selected requirement.
                    • Active UC_0083S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                    • Supported by the indexed evidence.
                    • specimen category excludes: Biofluid — Does not meet requirement
                      • The reported value differs from the selected requirement.
                      • Active UC_0083S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                    Source metadata
                    Source name
                    Human peripheral whole blood from endoscopically active UC patient
                    Characteristics
                    subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: no treatment; endoscopic_mayo_score: 1; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0; age (years): 29; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                    Description
                    Not reported
                    Indexed organism evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Indexed assay evidence
                    INFERRED · PARENT_INHERITED: Not reported
                    Source
                    GEO
                    Original indexed metadata
                    sample_accession: GSM2480253
                    sample_title: Active UC_0083S
                    source_name: Human peripheral whole blood from endoscopically active UC patient
                    characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: no treatment; endoscopic_mayo_score: 1; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0; age (years): 29; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                    GSM2480254

                    Excluded

                    Active UC_0087S

                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                    Requirements and decision evidence
                    • organism: Homo sapiens — Insufficient evidence
                      • The required value is not reported.
                      • assay type: bulk RNA-seq — Insufficient evidence
                        • The required value is not reported.
                        • specimen category: Tissue or biopsy — Does not meet requirement
                          • The reported value differs from the selected requirement.
                          • Active UC_0087S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                          • Supported by the indexed evidence.
                          • specimen category excludes: Biofluid — Does not meet requirement
                            • The reported value differs from the selected requirement.
                            • Active UC_0087S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                          Source metadata
                          Source name
                          Human peripheral whole blood from endoscopically active UC patient
                          Characteristics
                          subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Immunosupresor; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 4; age (years): 50; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                          Description
                          Not reported
                          Indexed organism evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Indexed assay evidence
                          INFERRED · PARENT_INHERITED: Not reported
                          Source
                          GEO
                          Original indexed metadata
                          sample_accession: GSM2480254
                          sample_title: Active UC_0087S
                          source_name: Human peripheral whole blood from endoscopically active UC patient
                          characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Immunosupresor; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 4; age (years): 50; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                          GSM2480255

                          Excluded

                          Active UC_0091S

                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                          Requirements and decision evidence
                          • organism: Homo sapiens — Insufficient evidence
                            • The required value is not reported.
                            • assay type: bulk RNA-seq — Insufficient evidence
                              • The required value is not reported.
                              • specimen category: Tissue or biopsy — Does not meet requirement
                                • The reported value differs from the selected requirement.
                                • Active UC_0091S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                • Supported by the indexed evidence.
                                • specimen category excludes: Biofluid — Does not meet requirement
                                  • The reported value differs from the selected requirement.
                                  • Active UC_0091S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                Source metadata
                                Source name
                                Human peripheral whole blood from endoscopically active UC patient
                                Characteristics
                                subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Steroids; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 12.5; age (years): 33; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                Description
                                Not reported
                                Indexed organism evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Indexed assay evidence
                                INFERRED · PARENT_INHERITED: Not reported
                                Source
                                GEO
                                Original indexed metadata
                                sample_accession: GSM2480255
                                sample_title: Active UC_0091S
                                source_name: Human peripheral whole blood from endoscopically active UC patient
                                characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: Steroids; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 12.5; age (years): 33; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                GSM2480256

                                Excluded

                                Active UC_0097S

                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                Requirements and decision evidence
                                • organism: Homo sapiens — Insufficient evidence
                                  • The required value is not reported.
                                  • assay type: bulk RNA-seq — Insufficient evidence
                                    • The required value is not reported.
                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                      • The reported value differs from the selected requirement.
                                      • Active UC_0097S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                      • Supported by the indexed evidence.
                                      • specimen category excludes: Biofluid — Does not meet requirement
                                        • The reported value differs from the selected requirement.
                                        • Active UC_0097S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                      Source metadata
                                      Source name
                                      Human peripheral whole blood from endoscopically active UC patient
                                      Characteristics
                                      subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: anti-TNF; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 2; age (years): 28; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                      Description
                                      Not reported
                                      Indexed organism evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Indexed assay evidence
                                      INFERRED · PARENT_INHERITED: Not reported
                                      Source
                                      GEO
                                      Original indexed metadata
                                      sample_accession: GSM2480256
                                      sample_title: Active UC_0097S
                                      source_name: Human peripheral whole blood from endoscopically active UC patient
                                      characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: anti-TNF; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 2; age (years): 28; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                      GSM2480257

                                      Excluded

                                      Active UC_0112S

                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                      Requirements and decision evidence
                                      • organism: Homo sapiens — Insufficient evidence
                                        • The required value is not reported.
                                        • assay type: bulk RNA-seq — Insufficient evidence
                                          • The required value is not reported.
                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                            • The reported value differs from the selected requirement.
                                            • Active UC_0112S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                            • Supported by the indexed evidence.
                                            • specimen category excludes: Biofluid — Does not meet requirement
                                              • The reported value differs from the selected requirement.
                                              • Active UC_0112S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                            Source metadata
                                            Source name
                                            Human peripheral whole blood from endoscopically active UC patient
                                            Characteristics
                                            subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11; age (years): 65; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                            Description
                                            Not reported
                                            Indexed organism evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Indexed assay evidence
                                            INFERRED · PARENT_INHERITED: Not reported
                                            Source
                                            GEO
                                            Original indexed metadata
                                            sample_accession: GSM2480257
                                            sample_title: Active UC_0112S
                                            source_name: Human peripheral whole blood from endoscopically active UC patient
                                            characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11; age (years): 65; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                            GSM2480258

                                            Excluded

                                            Active UC_0114S

                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                            Requirements and decision evidence
                                            • organism: Homo sapiens — Insufficient evidence
                                              • The required value is not reported.
                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                • The required value is not reported.
                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                  • The reported value differs from the selected requirement.
                                                  • Active UC_0114S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                  • Supported by the indexed evidence.
                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                    • The reported value differs from the selected requirement.
                                                    • Active UC_0114S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                  Source metadata
                                                  Source name
                                                  Human peripheral whole blood from endoscopically active UC patient
                                                  Characteristics
                                                  subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 10.5; age (years): 73; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                  Description
                                                  Not reported
                                                  Indexed organism evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Indexed assay evidence
                                                  INFERRED · PARENT_INHERITED: Not reported
                                                  Source
                                                  GEO
                                                  Original indexed metadata
                                                  sample_accession: GSM2480258
                                                  sample_title: Active UC_0114S
                                                  source_name: Human peripheral whole blood from endoscopically active UC patient
                                                  characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 10.5; age (years): 73; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                  GSM2480259

                                                  Excluded

                                                  Active UC_0145S

                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                  Requirements and decision evidence
                                                  • organism: Homo sapiens — Insufficient evidence
                                                    • The required value is not reported.
                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                      • The required value is not reported.
                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                        • The reported value differs from the selected requirement.
                                                        • Active UC_0145S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                        • Supported by the indexed evidence.
                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                          • The reported value differs from the selected requirement.
                                                          • Active UC_0145S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                        Source metadata
                                                        Source name
                                                        Human peripheral whole blood from endoscopically active UC patient
                                                        Characteristics
                                                        subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 15; age (years): 56; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                        Description
                                                        Not reported
                                                        Indexed organism evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Indexed assay evidence
                                                        INFERRED · PARENT_INHERITED: Not reported
                                                        Source
                                                        GEO
                                                        Original indexed metadata
                                                        sample_accession: GSM2480259
                                                        sample_title: Active UC_0145S
                                                        source_name: Human peripheral whole blood from endoscopically active UC patient
                                                        characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 15; age (years): 56; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                        GSM2480260

                                                        Excluded

                                                        Active UC_0155S

                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                        Requirements and decision evidence
                                                        • organism: Homo sapiens — Insufficient evidence
                                                          • The required value is not reported.
                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                            • The required value is not reported.
                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                              • The reported value differs from the selected requirement.
                                                              • Active UC_0155S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                              • Supported by the indexed evidence.
                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                • The reported value differs from the selected requirement.
                                                                • Active UC_0155S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                              Source metadata
                                                              Source name
                                                              Human peripheral whole blood from endoscopically active UC patient
                                                              Characteristics
                                                              subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 14; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                              Description
                                                              Not reported
                                                              Indexed organism evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Indexed assay evidence
                                                              INFERRED · PARENT_INHERITED: Not reported
                                                              Source
                                                              GEO
                                                              Original indexed metadata
                                                              sample_accession: GSM2480260
                                                              sample_title: Active UC_0155S
                                                              source_name: Human peripheral whole blood from endoscopically active UC patient
                                                              characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 14; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                              GSM2480261

                                                              Excluded

                                                              Active UC_0164S

                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                              Requirements and decision evidence
                                                              • organism: Homo sapiens — Insufficient evidence
                                                                • The required value is not reported.
                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                  • The required value is not reported.
                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                    • The reported value differs from the selected requirement.
                                                                    • Active UC_0164S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                    • Supported by the indexed evidence.
                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                      • The reported value differs from the selected requirement.
                                                                      • Active UC_0164S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                    Source metadata
                                                                    Source name
                                                                    Human peripheral whole blood from endoscopically active UC patient
                                                                    Characteristics
                                                                    subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 10.5; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                    Description
                                                                    Not reported
                                                                    Indexed organism evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Indexed assay evidence
                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                    Source
                                                                    GEO
                                                                    Original indexed metadata
                                                                    sample_accession: GSM2480261
                                                                    sample_title: Active UC_0164S
                                                                    source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                    characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 10.5; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                    GSM2480262

                                                                    Excluded

                                                                    Active UC_0169S

                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                    Requirements and decision evidence
                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                      • The required value is not reported.
                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                        • The required value is not reported.
                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                          • The reported value differs from the selected requirement.
                                                                          • Active UC_0169S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                          • Supported by the indexed evidence.
                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                            • The reported value differs from the selected requirement.
                                                                            • Active UC_0169S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                          Source metadata
                                                                          Source name
                                                                          Human peripheral whole blood from endoscopically active UC patient
                                                                          Characteristics
                                                                          subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: no treatment; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11.5; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                          Description
                                                                          Not reported
                                                                          Indexed organism evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Indexed assay evidence
                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                          Source
                                                                          GEO
                                                                          Original indexed metadata
                                                                          sample_accession: GSM2480262
                                                                          sample_title: Active UC_0169S
                                                                          source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                          characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: no treatment; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11.5; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                          GSM2480263

                                                                          Excluded

                                                                          Active UC_0182S

                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                          Requirements and decision evidence
                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                            • The required value is not reported.
                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                              • The required value is not reported.
                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                • The reported value differs from the selected requirement.
                                                                                • Active UC_0182S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                • Supported by the indexed evidence.
                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                  • The reported value differs from the selected requirement.
                                                                                  • Active UC_0182S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                Source metadata
                                                                                Source name
                                                                                Human peripheral whole blood from endoscopically active UC patient
                                                                                Characteristics
                                                                                subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 2.5; age (years): 39; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                Description
                                                                                Not reported
                                                                                Indexed organism evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Indexed assay evidence
                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                Source
                                                                                GEO
                                                                                Original indexed metadata
                                                                                sample_accession: GSM2480263
                                                                                sample_title: Active UC_0182S
                                                                                source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                                characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 2.5; age (years): 39; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                GSM2480264

                                                                                Excluded

                                                                                Active UC_0186S

                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                Requirements and decision evidence
                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                  • The required value is not reported.
                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                    • The required value is not reported.
                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                      • The reported value differs from the selected requirement.
                                                                                      • Active UC_0186S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                      • Supported by the indexed evidence.
                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                        • The reported value differs from the selected requirement.
                                                                                        • Active UC_0186S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                      Source metadata
                                                                                      Source name
                                                                                      Human peripheral whole blood from endoscopically active UC patient
                                                                                      Characteristics
                                                                                      subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                      Description
                                                                                      Not reported
                                                                                      Indexed organism evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Indexed assay evidence
                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                      Source
                                                                                      GEO
                                                                                      Original indexed metadata
                                                                                      sample_accession: GSM2480264
                                                                                      sample_title: Active UC_0186S
                                                                                      source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                                      characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 0; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                      GSM2480265

                                                                                      Excluded

                                                                                      Active UC_0218S

                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                      Requirements and decision evidence
                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                        • The required value is not reported.
                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                          • The required value is not reported.
                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                            • The reported value differs from the selected requirement.
                                                                                            • Active UC_0218S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                            • Supported by the indexed evidence.
                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                              • The reported value differs from the selected requirement.
                                                                                              • Active UC_0218S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                            Source metadata
                                                                                            Source name
                                                                                            Human peripheral whole blood from endoscopically active UC patient
                                                                                            Characteristics
                                                                                            subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 9; age (years): 45; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                            Description
                                                                                            Not reported
                                                                                            Indexed organism evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Indexed assay evidence
                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                            Source
                                                                                            GEO
                                                                                            Original indexed metadata
                                                                                            sample_accession: GSM2480265
                                                                                            sample_title: Active UC_0218S
                                                                                            source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                                            characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Left-sided colitis; treatment: 5-asa; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 9; age (years): 45; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                            GSM2480266

                                                                                            Excluded

                                                                                            Active UC_0219S

                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                            Requirements and decision evidence
                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                              • The required value is not reported.
                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                • The required value is not reported.
                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                  • The reported value differs from the selected requirement.
                                                                                                  • Active UC_0219S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                  • Supported by the indexed evidence.
                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                    • The reported value differs from the selected requirement.
                                                                                                    • Active UC_0219S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                                  Source metadata
                                                                                                  Source name
                                                                                                  Human peripheral whole blood from endoscopically active UC patient
                                                                                                  Characteristics
                                                                                                  subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: anti-TNF; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 6.5; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                  Description
                                                                                                  Not reported
                                                                                                  Indexed organism evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Indexed assay evidence
                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                  Source
                                                                                                  GEO
                                                                                                  Original indexed metadata
                                                                                                  sample_accession: GSM2480266
                                                                                                  sample_title: Active UC_0219S
                                                                                                  source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                                                  characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Pancolitis; treatment: anti-TNF; endoscopic_mayo_score: 3; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 6.5; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                  GSM2480267

                                                                                                  Excluded

                                                                                                  Active UC_0419S

                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                  Requirements and decision evidence
                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                    • The required value is not reported.
                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                      • The required value is not reported.
                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                        • The reported value differs from the selected requirement.
                                                                                                        • Active UC_0419S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                        • Supported by the indexed evidence.
                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                          • The reported value differs from the selected requirement.
                                                                                                          • Active UC_0419S Human peripheral whole blood from endoscopically active UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity:...
                                                                                                        Source metadata
                                                                                                        Source name
                                                                                                        Human peripheral whole blood from endoscopically active UC patient
                                                                                                        Characteristics
                                                                                                        subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 17; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                        Description
                                                                                                        Not reported
                                                                                                        Indexed organism evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Indexed assay evidence
                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                        Source
                                                                                                        GEO
                                                                                                        Original indexed metadata
                                                                                                        sample_accession: GSM2480267
                                                                                                        sample_title: Active UC_0419S
                                                                                                        source_name: Human peripheral whole blood from endoscopically active UC patient
                                                                                                        characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Active; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 2; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 17; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                        GSM2480268

                                                                                                        Excluded

                                                                                                        Inactive UC_0043S

                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                        Requirements and decision evidence
                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                          • The required value is not reported.
                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                            • The required value is not reported.
                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                              • The reported value differs from the selected requirement.
                                                                                                              • Inactive UC_0043S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                              • Supported by the indexed evidence.
                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                • Inactive UC_0043S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                              Source metadata
                                                                                                              Source name
                                                                                                              Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                              Characteristics
                                                                                                              subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 32.5; age (years): 52; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                              Description
                                                                                                              Not reported
                                                                                                              Indexed organism evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Indexed assay evidence
                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                              Source
                                                                                                              GEO
                                                                                                              Original indexed metadata
                                                                                                              sample_accession: GSM2480268
                                                                                                              sample_title: Inactive UC_0043S
                                                                                                              source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                              characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 32.5; age (years): 52; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                              GSM2480269

                                                                                                              Excluded

                                                                                                              Inactive UC_0053S

                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                              Requirements and decision evidence
                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                • The required value is not reported.
                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                  • The required value is not reported.
                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                    • Inactive UC_0053S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                    • Supported by the indexed evidence.
                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                      • Inactive UC_0053S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                    Source metadata
                                                                                                                    Source name
                                                                                                                    Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                    Characteristics
                                                                                                                    subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13; age (years): 60; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                    Description
                                                                                                                    Not reported
                                                                                                                    Indexed organism evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Indexed assay evidence
                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                    Source
                                                                                                                    GEO
                                                                                                                    Original indexed metadata
                                                                                                                    sample_accession: GSM2480269
                                                                                                                    sample_title: Inactive UC_0053S
                                                                                                                    source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                    characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13; age (years): 60; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                    GSM2480270

                                                                                                                    Excluded

                                                                                                                    Inactive UC_0103S

                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                    Requirements and decision evidence
                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                      • The required value is not reported.
                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                        • The required value is not reported.
                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                          • Inactive UC_0103S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                          • Supported by the indexed evidence.
                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                            • Inactive UC_0103S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                          Source metadata
                                                                                                                          Source name
                                                                                                                          Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                          Characteristics
                                                                                                                          subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: No treatment; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11; age (years): 52; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                          Description
                                                                                                                          Not reported
                                                                                                                          Indexed organism evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Indexed assay evidence
                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                          Source
                                                                                                                          GEO
                                                                                                                          Original indexed metadata
                                                                                                                          sample_accession: GSM2480270
                                                                                                                          sample_title: Inactive UC_0103S
                                                                                                                          source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                          characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: No treatment; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 11; age (years): 52; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                          GSM2480271

                                                                                                                          Excluded

                                                                                                                          Inactive UC_0125S

                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                          Requirements and decision evidence
                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                            • The required value is not reported.
                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                              • The required value is not reported.
                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                • Inactive UC_0125S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                  • Inactive UC_0125S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                Source metadata
                                                                                                                                Source name
                                                                                                                                Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                Characteristics
                                                                                                                                subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: No treatment; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13; age (years): 43; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                Description
                                                                                                                                Not reported
                                                                                                                                Indexed organism evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Indexed assay evidence
                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                Source
                                                                                                                                GEO
                                                                                                                                Original indexed metadata
                                                                                                                                sample_accession: GSM2480271
                                                                                                                                sample_title: Inactive UC_0125S
                                                                                                                                source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: No treatment; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13; age (years): 43; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                GSM2480272

                                                                                                                                Excluded

                                                                                                                                Inactive UC_0135S

                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                                                Requirements and decision evidence
                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                  • The required value is not reported.
                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                    • The required value is not reported.
                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                      • Inactive UC_0135S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                        • Inactive UC_0135S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                      Source metadata
                                                                                                                                      Source name
                                                                                                                                      Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                      Characteristics
                                                                                                                                      subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: Immunosupressors; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 29; age (years): 41; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                      Description
                                                                                                                                      Not reported
                                                                                                                                      Indexed organism evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Indexed assay evidence
                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                      Source
                                                                                                                                      GEO
                                                                                                                                      Original indexed metadata
                                                                                                                                      sample_accession: GSM2480272
                                                                                                                                      sample_title: Inactive UC_0135S
                                                                                                                                      source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                      characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Left-sided colitis; treatment: Immunosupressors; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 29; age (years): 41; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                      GSM2480273

                                                                                                                                      Excluded

                                                                                                                                      Inactive UC_0159S

                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                                                      Requirements and decision evidence
                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                        • The required value is not reported.
                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                          • The required value is not reported.
                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                            • Inactive UC_0159S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                              • Inactive UC_0159S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                            Source metadata
                                                                                                                                            Source name
                                                                                                                                            Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                            Characteristics
                                                                                                                                            subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 19; age (years): 37; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                            Description
                                                                                                                                            Not reported
                                                                                                                                            Indexed organism evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Indexed assay evidence
                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                            Source
                                                                                                                                            GEO
                                                                                                                                            Original indexed metadata
                                                                                                                                            sample_accession: GSM2480273
                                                                                                                                            sample_title: Inactive UC_0159S
                                                                                                                                            source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                            characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Pancolitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 19; age (years): 37; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                            GSM2480274

                                                                                                                                            Excluded

                                                                                                                                            Inactive UC_0307S

                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                                                            Requirements and decision evidence
                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                              • The required value is not reported.
                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                • The required value is not reported.
                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                  • Inactive UC_0307S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                    • Inactive UC_0307S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                                  Source metadata
                                                                                                                                                  Source name
                                                                                                                                                  Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                                  Characteristics
                                                                                                                                                  subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 12.5; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                  Description
                                                                                                                                                  Not reported
                                                                                                                                                  Indexed organism evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Indexed assay evidence
                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                  Source
                                                                                                                                                  GEO
                                                                                                                                                  Original indexed metadata
                                                                                                                                                  sample_accession: GSM2480274
                                                                                                                                                  sample_title: Inactive UC_0307S
                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                                  characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 12.5; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                  GSM2480275

                                                                                                                                                  Excluded

                                                                                                                                                  Inactive UC_0308S

                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Explicit sample label case marker detected.

                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                    • The required value is not reported.
                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                      • The required value is not reported.
                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                        • Inactive UC_0308S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                          • Inactive UC_0308S Human peripheral whole blood from endoscopically inactive UC patient subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activ...
                                                                                                                                                        Source metadata
                                                                                                                                                        Source name
                                                                                                                                                        Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                                        Characteristics
                                                                                                                                                        subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13.5; age (years): 58; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                        Description
                                                                                                                                                        Not reported
                                                                                                                                                        Indexed organism evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Indexed assay evidence
                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                        Source
                                                                                                                                                        GEO
                                                                                                                                                        Original indexed metadata
                                                                                                                                                        sample_accession: GSM2480275
                                                                                                                                                        sample_title: Inactive UC_0308S
                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically inactive UC patient
                                                                                                                                                        characteristics: subject status: Ulcerative colitis (UC) patient; case_phenotype: Colitis; endoscopic_activity: Inactive; disease_extension: Proctitis; treatment: 5-asa; endoscopic_mayo_score: 0; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 13.5; age (years): 58; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                        GSM2480276

                                                                                                                                                        Excluded

                                                                                                                                                        Control_0152S

                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                          • The required value is not reported.
                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                            • The required value is not reported.
                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                              • Control_0152S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                • Control_0152S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                              Source metadata
                                                                                                                                                              Source name
                                                                                                                                                              Human peripheral whole blood from non-IBD control
                                                                                                                                                              Characteristics
                                                                                                                                                              subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                              Description
                                                                                                                                                              Not reported
                                                                                                                                                              Indexed organism evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Indexed assay evidence
                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                              Source
                                                                                                                                                              GEO
                                                                                                                                                              Original indexed metadata
                                                                                                                                                              sample_accession: GSM2480276
                                                                                                                                                              sample_title: Control_0152S
                                                                                                                                                              source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                              characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                              GSM2480277

                                                                                                                                                              Excluded

                                                                                                                                                              Control_0153S

                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                    • Control_0153S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                      • Control_0153S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                    Source metadata
                                                                                                                                                                    Source name
                                                                                                                                                                    Human peripheral whole blood from non-IBD control
                                                                                                                                                                    Characteristics
                                                                                                                                                                    subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 39; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                    Description
                                                                                                                                                                    Not reported
                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                    Source
                                                                                                                                                                    GEO
                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                    sample_accession: GSM2480277
                                                                                                                                                                    sample_title: Control_0153S
                                                                                                                                                                    source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                    characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 39; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                    GSM2480278

                                                                                                                                                                    Excluded

                                                                                                                                                                    Control_0154S

                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                          • Control_0154S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                            • Control_0154S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                          Source metadata
                                                                                                                                                                          Source name
                                                                                                                                                                          Human peripheral whole blood from non-IBD control
                                                                                                                                                                          Characteristics
                                                                                                                                                                          subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 39; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                          Description
                                                                                                                                                                          Not reported
                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                          Source
                                                                                                                                                                          GEO
                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                          sample_accession: GSM2480278
                                                                                                                                                                          sample_title: Control_0154S
                                                                                                                                                                          source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                          characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 39; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                          GSM2480279

                                                                                                                                                                          Excluded

                                                                                                                                                                          Control_0156S

                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                • Control_0156S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                  • Control_0156S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                Source metadata
                                                                                                                                                                                Source name
                                                                                                                                                                                Human peripheral whole blood from non-IBD control
                                                                                                                                                                                Characteristics
                                                                                                                                                                                subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 34; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                Description
                                                                                                                                                                                Not reported
                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                Source
                                                                                                                                                                                GEO
                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                sample_accession: GSM2480279
                                                                                                                                                                                sample_title: Control_0156S
                                                                                                                                                                                source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 34; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                GSM2480280

                                                                                                                                                                                Excluded

                                                                                                                                                                                Control_0170S

                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                      • Control_0170S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                        • Control_0170S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                      Source metadata
                                                                                                                                                                                      Source name
                                                                                                                                                                                      Human peripheral whole blood from non-IBD control
                                                                                                                                                                                      Characteristics
                                                                                                                                                                                      subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                      Description
                                                                                                                                                                                      Not reported
                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                      Source
                                                                                                                                                                                      GEO
                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                      sample_accession: GSM2480280
                                                                                                                                                                                      sample_title: Control_0170S
                                                                                                                                                                                      source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                      characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                      GSM2480281

                                                                                                                                                                                      Excluded

                                                                                                                                                                                      Control_0185S

                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                            • Control_0185S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                              • Control_0185S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                            Source metadata
                                                                                                                                                                                            Source name
                                                                                                                                                                                            Human peripheral whole blood from non-IBD control
                                                                                                                                                                                            Characteristics
                                                                                                                                                                                            subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                            Description
                                                                                                                                                                                            Not reported
                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                            Source
                                                                                                                                                                                            GEO
                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                            sample_accession: GSM2480281
                                                                                                                                                                                            sample_title: Control_0185S
                                                                                                                                                                                            source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                            characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                            GSM2480282

                                                                                                                                                                                            Excluded

                                                                                                                                                                                            Control_0193S

                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                  • Control_0193S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                    • Control_0193S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                  Source name
                                                                                                                                                                                                  Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                  subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 57; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                  Description
                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                  Source
                                                                                                                                                                                                  GEO
                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                  sample_accession: GSM2480282
                                                                                                                                                                                                  sample_title: Control_0193S
                                                                                                                                                                                                  source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                  characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 57; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                  GSM2480283

                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                  Control_0200S

                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                        • Control_0200S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                          • Control_0200S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                        Source name
                                                                                                                                                                                                        Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                        subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 44; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                        Description
                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                        Source
                                                                                                                                                                                                        GEO
                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                        sample_accession: GSM2480283
                                                                                                                                                                                                        sample_title: Control_0200S
                                                                                                                                                                                                        source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                        characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 44; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                        GSM2480284

                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                        Control_0201S

                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                              • Control_0201S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                • Control_0201S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                              Source name
                                                                                                                                                                                                              Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                              subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 51; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                              Description
                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                              Source
                                                                                                                                                                                                              GEO
                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                              sample_accession: GSM2480284
                                                                                                                                                                                                              sample_title: Control_0201S
                                                                                                                                                                                                              source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                              characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 51; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                              GSM2480285

                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                              Control_0211S

                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                    • Control_0211S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                      • Control_0211S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                    Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                    subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                    sample_accession: GSM2480285
                                                                                                                                                                                                                    sample_title: Control_0211S
                                                                                                                                                                                                                    source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                    characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                    GSM2480286

                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                    Control_0211Sbis

                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                          • Control_0211Sbis Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n....
                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                            • Control_0211Sbis Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n....
                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                          Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                          subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                          sample_accession: GSM2480286
                                                                                                                                                                                                                          sample_title: Control_0211Sbis
                                                                                                                                                                                                                          source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                          characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 49; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                          GSM2480287

                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                          Control_0212S

                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                • Control_0212S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                  • Control_0212S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                sample_accession: GSM2480287
                                                                                                                                                                                                                                sample_title: Control_0212S
                                                                                                                                                                                                                                source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                GSM2480288

                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                Control_0212Sbis

                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                      • Control_0212Sbis Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n....
                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                        • Control_0212Sbis Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n....
                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                      Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                      subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                      sample_accession: GSM2480288
                                                                                                                                                                                                                                      sample_title: Control_0212Sbis
                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                      characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                      GSM2480289

                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                      Control_0213S

                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                            • Control_0213S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                              • Control_0213S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                            Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                            subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 50; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                            sample_accession: GSM2480289
                                                                                                                                                                                                                                            sample_title: Control_0213S
                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                            characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 50; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                            GSM2480290

                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                            Control_0214S

                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                  • Control_0214S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                    • Control_0214S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                  Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                  subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 31; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                  sample_accession: GSM2480290
                                                                                                                                                                                                                                                  sample_title: Control_0214S
                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                  characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 31; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                  GSM2480291

                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                  Control_0215S

                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                        • Control_0215S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                          • Control_0215S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                        Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                        subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 38; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                        sample_accession: GSM2480291
                                                                                                                                                                                                                                                        sample_title: Control_0215S
                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                        characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 38; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                        GSM2480292

                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                        Control_0222S

                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                              • Control_0222S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                • Control_0222S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                              Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                              subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                              sample_accession: GSM2480292
                                                                                                                                                                                                                                                              sample_title: Control_0222S
                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                              characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                              GSM2480293

                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                              Control_0223S

                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                    • Control_0223S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                      • Control_0223S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                    Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                    subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 38; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                    sample_accession: GSM2480293
                                                                                                                                                                                                                                                                    sample_title: Control_0223S
                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                    characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 38; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                    GSM2480294

                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                    Control_0224S

                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                          • Control_0224S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                            • Control_0224S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                          Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                          subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                          sample_accession: GSM2480294
                                                                                                                                                                                                                                                                          sample_title: Control_0224S
                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                          characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                          GSM2480295

                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                          Control_0229S

                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                • Control_0229S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                  • Control_0229S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                sample_accession: GSM2480295
                                                                                                                                                                                                                                                                                sample_title: Control_0229S
                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                GSM2480296

                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                Control_0249S

                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                      • Control_0249S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                        • Control_0249S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                      Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                      subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                      sample_accession: GSM2480296
                                                                                                                                                                                                                                                                                      sample_title: Control_0249S
                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                      characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 54; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                      GSM2480297

                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                      Control_0420S

                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Sample-local control marker detected.

                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                            • Control_0420S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                              • Control_0420S Human peripheral whole blood from non-IBD control subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.;...
                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                            Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                            subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                            sample_accession: GSM2480297
                                                                                                                                                                                                                                                                                            sample_title: Control_0420S
                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from non-IBD control
                                                                                                                                                                                                                                                                                            characteristics: subject status: non-IBD (inflammatory bowel disease) control; case_phenotype: Control; endoscopic_activity: n.a.; disease_extension: n.a.; treatment: n.a.; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): n.a.; age (years): 55; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                            GSM2480298

                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                            Active CD_0143S

                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                  • Active CD_0143S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                    • Active CD_0143S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 11.5; partial cdeis: 18; ibd_evolution_time (years): 28; age (years): 48; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480298
                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0143S
                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 11.5; partial cdeis: 18; ibd_evolution_time (years): 28; age (years): 48; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                  GSM2480299

                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                  Active CD_0143Sbis

                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                        • Active CD_0143Sbis Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: A...
                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                          • Active CD_0143Sbis Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: A...
                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 11.5; partial cdeis: 18; ibd_evolution_time (years): 28; age (years): 48; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480299
                                                                                                                                                                                                                                                                                                        sample_title: Active CD_0143Sbis
                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 11.5; partial cdeis: 18; ibd_evolution_time (years): 28; age (years): 48; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                        GSM2480300

                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                        Active CD_0144S

                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                              • Active CD_0144S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                • Active CD_0144S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 14; partial cdeis: 25; ibd_evolution_time (years): 9; age (years): 30; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480300
                                                                                                                                                                                                                                                                                                              sample_title: Active CD_0144S
                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 14; partial cdeis: 25; ibd_evolution_time (years): 9; age (years): 30; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                              GSM2480301

                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                              Active CD_0157S

                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                    • Active CD_0157S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                      • Active CD_0157S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 14.8; partial cdeis: 24; ibd_evolution_time (years): 1; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480301
                                                                                                                                                                                                                                                                                                                    sample_title: Active CD_0157S
                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: anti-TNF + Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 14.8; partial cdeis: 24; ibd_evolution_time (years): 1; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                    GSM2480302

                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                    Active CD_0342S

                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                          • Active CD_0342S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                            • Active CD_0342S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 36.4; partial cdeis: 28; ibd_evolution_time (years): 0; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480302
                                                                                                                                                                                                                                                                                                                          sample_title: Active CD_0342S
                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 36.4; partial cdeis: 28; ibd_evolution_time (years): 0; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                          GSM2480303

                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                          Active CD_0438S

                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                • Active CD_0438S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                  • Active CD_0438S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 19.8; partial cdeis: 21.5; ibd_evolution_time (years): 0.4; age (years): 21; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480303
                                                                                                                                                                                                                                                                                                                                sample_title: Active CD_0438S
                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 19.8; partial cdeis: 21.5; ibd_evolution_time (years): 0.4; age (years): 21; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                GSM2480304

                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                Active CD_0036S

                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                      • Active CD_0036S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                        • Active CD_0036S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 9; ibd_evolution_time (years): 32; age (years): 56; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480304
                                                                                                                                                                                                                                                                                                                                      sample_title: Active CD_0036S
                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 9; ibd_evolution_time (years): 32; age (years): 56; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                      GSM2480305

                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                      Active CD_0037S

                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                            • Active CD_0037S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                              • Active CD_0037S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 4; partial cdeis: 7; ibd_evolution_time (years): 15; age (years): 49; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480305
                                                                                                                                                                                                                                                                                                                                            sample_title: Active CD_0037S
                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 4; partial cdeis: 7; ibd_evolution_time (years): 15; age (years): 49; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                            GSM2480306

                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                            Active CD_0051S

                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                  • Active CD_0051S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                    • Active CD_0051S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 4.6; partial cdeis: 23; ibd_evolution_time (years): 9.5; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480306
                                                                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0051S
                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 4.6; partial cdeis: 23; ibd_evolution_time (years): 9.5; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                  GSM2480307

                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                  Active CD_0057S

                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                        • Active CD_0057S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                          • Active CD_0057S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 12; ibd_evolution_time (years): 7.5; age (years): 43; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480307
                                                                                                                                                                                                                                                                                                                                                        sample_title: Active CD_0057S
                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 12; ibd_evolution_time (years): 7.5; age (years): 43; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                        GSM2480308

                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                        Active CD_0069S

                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                              • Active CD_0069S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                • Active CD_0069S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 5.4; partial cdeis: 16; ibd_evolution_time (years): 5; age (years): 24; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480308
                                                                                                                                                                                                                                                                                                                                                              sample_title: Active CD_0069S
                                                                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 5.4; partial cdeis: 16; ibd_evolution_time (years): 5; age (years): 24; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                              GSM2480309

                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                              Active CD_0084S

                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0084S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0084S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Steroids; endoscopic_mayo_score: n.a.; cdeis: 10; partial cdeis: 26; ibd_evolution_time (years): 0; age (years): 54; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480309
                                                                                                                                                                                                                                                                                                                                                                    sample_title: Active CD_0084S
                                                                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Steroids; endoscopic_mayo_score: n.a.; cdeis: 10; partial cdeis: 26; ibd_evolution_time (years): 0; age (years): 54; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                    GSM2480310

                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                    Active CD_0089S

                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0089S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0089S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Steroids; endoscopic_mayo_score: n.a.; cdeis: 4.6; partial cdeis: 9; ibd_evolution_time (years): 9.5; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480310
                                                                                                                                                                                                                                                                                                                                                                          sample_title: Active CD_0089S
                                                                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Steroids; endoscopic_mayo_score: n.a.; cdeis: 4.6; partial cdeis: 9; ibd_evolution_time (years): 9.5; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                          GSM2480311

                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                          Active CD_0090S

                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0090S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0090S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 3; age (years): 52; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480311
                                                                                                                                                                                                                                                                                                                                                                                sample_title: Active CD_0090S
                                                                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 3; age (years): 52; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                GSM2480312

                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                Active CD_0093S

                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0093S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0093S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 17; partial cdeis: 21; ibd_evolution_time (years): 15; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480312
                                                                                                                                                                                                                                                                                                                                                                                      sample_title: Active CD_0093S
                                                                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 17; partial cdeis: 21; ibd_evolution_time (years): 15; age (years): 35; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                      GSM2480313

                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                      Active CD_0100S

                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0100S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0100S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 21.75; partial cdeis: 38; ibd_evolution_time (years): 0.7; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480313
                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Active CD_0100S
                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 21.75; partial cdeis: 38; ibd_evolution_time (years): 0.7; age (years): 47; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                            GSM2480314

                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                            Active CD_0108S

                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0108S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0108S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 5; partial cdeis: 24; ibd_evolution_time (years): 1; age (years): 29; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480314
                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0108S
                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 5; partial cdeis: 24; ibd_evolution_time (years): 1; age (years): 29; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                  GSM2480315

                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                  Active CD_0110S

                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0110S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0110S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 12.5; partial cdeis: 30; ibd_evolution_time (years): 12; age (years): 20; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480315
                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Active CD_0110S
                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 12.5; partial cdeis: 30; ibd_evolution_time (years): 12; age (years): 20; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                        GSM2480316

                                                                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                                                                        Active CD_0115S

                                                                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0115S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0115S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 24; age (years): 46; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480316
                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Active CD_0115S
                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 24; age (years): 46; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                              GSM2480317

                                                                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                                                                              Active CD_0128S

                                                                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0128S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0128S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 2; partial cdeis: 10; ibd_evolution_time (years): 18.5; age (years): 41; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480317
                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Active CD_0128S
                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 2; partial cdeis: 10; ibd_evolution_time (years): 18.5; age (years): 41; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                    GSM2480318

                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                    Active CD_0130S

                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0130S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0130S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 13.8; partial cdeis: 26; ibd_evolution_time (years): 1.5; age (years): 33; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480318
                                                                                                                                                                                                                                                                                                                                                                                                                          sample_title: Active CD_0130S
                                                                                                                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 13.8; partial cdeis: 26; ibd_evolution_time (years): 1.5; age (years): 33; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                          GSM2480319

                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                          Active CD_0137S

                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0137S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0137S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 8.2; partial cdeis: 29; ibd_evolution_time (years): 8; age (years): 31; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480319
                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Active CD_0137S
                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 8.2; partial cdeis: 29; ibd_evolution_time (years): 8; age (years): 31; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                GSM2480320

                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                Active CD_0142S

                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0142S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0142S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 3.4; partial cdeis: 17; ibd_evolution_time (years): 10; age (years): 67; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480320
                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_title: Active CD_0142S
                                                                                                                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 3.4; partial cdeis: 17; ibd_evolution_time (years): 10; age (years): 67; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM2480321

                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                      Active CD_0181S

                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0181S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0181S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 12.2; partial cdeis: 37; ibd_evolution_time (years): 10.5; age (years): 23; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480321
                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Active CD_0181S
                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 12.2; partial cdeis: 37; ibd_evolution_time (years): 10.5; age (years): 23; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM2480322

                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                            Active CD_0225S

                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0225S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0225S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 9.5; partial cdeis: 27; ibd_evolution_time (years): 3.5; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480322
                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0225S
                                                                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 9.5; partial cdeis: 27; ibd_evolution_time (years): 3.5; age (years): 29; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM2480323

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Active CD_0258S

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0258S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0258S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 30; partial cdeis: 30; ibd_evolution_time (years): 3.5; age (years): 32; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480323
                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Active CD_0258S
                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 30; partial cdeis: 30; ibd_evolution_time (years): 3.5; age (years): 32; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM2480324

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Active CD_0258Sbis

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0258Sbis Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: A...
                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0258Sbis Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: A...
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 30; partial cdeis: 30; ibd_evolution_time (years): 3.5; age (years): 32; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480324
                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Active CD_0258Sbis
                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: colonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 30; partial cdeis: 30; ibd_evolution_time (years): 3.5; age (years): 32; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM2480325

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Active CD_0273S

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0273S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0273S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 3.4; partial cdeis: 17; ibd_evolution_time (years): 4.5; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480325
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Active CD_0273S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 3.4; partial cdeis: 17; ibd_evolution_time (years): 4.5; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM2480326

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Active CD_0312S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0312S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0312S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 6.5; partial cdeis: n.a.; ibd_evolution_time (years): 3; age (years): 18; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480326
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_title: Active CD_0312S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 6.5; partial cdeis: n.a.; ibd_evolution_time (years): 3; age (years): 18; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM2480327

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Active CD_0377S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0377S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0377S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 2.4; partial cdeis: 14; ibd_evolution_time (years): 13.5; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480327
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Active CD_0377S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 2.4; partial cdeis: 14; ibd_evolution_time (years): 13.5; age (years): 35; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM2480328

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Active CD_0405S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0405S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0405S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 5.4; partial cdeis: 21; ibd_evolution_time (years): 12; age (years): 21; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480328
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_title: Active CD_0405S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 5.4; partial cdeis: 21; ibd_evolution_time (years): 12; age (years): 21; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM2480329

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Active CD_0412S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0412S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0412S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4; partial cdeis: 20; ibd_evolution_time (years): 19; age (years): 40; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480329
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Active CD_0412S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 4; partial cdeis: 20; ibd_evolution_time (years): 19; age (years): 40; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM2480330

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Active CD_0415S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0415S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0415S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 10; age (years): 32; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480330
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0415S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 4.8; partial cdeis: 24; ibd_evolution_time (years): 10; age (years): 32; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM2480331

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Active CD_0416S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0416S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0416S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 7.6; partial cdeis: 23; ibd_evolution_time (years): 13; age (years): 50; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480331
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Active CD_0416S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 7.6; partial cdeis: 23; ibd_evolution_time (years): 13; age (years): 50; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM2480332

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Active CD_0421S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0421S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0421S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 11.28; partial cdeis: 25; ibd_evolution_time (years): 7; age (years): 37; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480332
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Active CD_0421S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 11.28; partial cdeis: 25; ibd_evolution_time (years): 7; age (years): 37; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM2480333

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Active CD_0423S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0423S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0423S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 9.2; partial cdeis: 21; ibd_evolution_time (years): 0.6; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480333
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Active CD_0423S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor + Steroids; endoscopic_mayo_score: n.a.; cdeis: 9.2; partial cdeis: 21; ibd_evolution_time (years): 0.6; age (years): 57; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM2480334

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Active CD_0431S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Active CD_0431S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0431S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 3.2; partial cdeis: 16; ibd_evolution_time (years): 0.4; age (years): 28; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480334
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_title: Active CD_0431S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 3.2; partial cdeis: 16; ibd_evolution_time (years): 0.4; age (years): 28; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM2480335

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Active CD_0440S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Active CD_0440S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0440S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 5.6; partial cdeis: 14; ibd_evolution_time (years): 2; age (years): 22; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480335
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Active CD_0440S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: Immunosupresor; endoscopic_mayo_score: n.a.; cdeis: 5.6; partial cdeis: 14; ibd_evolution_time (years): 2; age (years): 22; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM2480336

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Active CD_0441S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Active CD_0441S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Active CD_0441S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 22.6; partial cdeis: 25; ibd_evolution_time (years): 1; age (years): 28; gender: Female; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480336
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_title: Active CD_0441S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 22.6; partial cdeis: 25; ibd_evolution_time (years): 1; age (years): 28; gender: Female; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM2480337

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Active CD_0445S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Active CD_0445S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Active CD_0445S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 6.4; partial cdeis: 32; ibd_evolution_time (years): 0; age (years): 64; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480337
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Active CD_0445S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: no treatment; endoscopic_mayo_score: n.a.; cdeis: 6.4; partial cdeis: 32; ibd_evolution_time (years): 0; age (years): 64; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM2480338

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Active CD_0076S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Active CD_0076S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Active CD_0076S Human peripheral whole blood from endoscopically active CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Acti...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Steroids; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 1.5; age (years): 27; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480338
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Active CD_0076S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically active CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Active; disease_extension: ileal; treatment: anti-TNF + Steroids; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 1.5; age (years): 27; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM2480339

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Inactive CD_0092S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Inactive CD_0092S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Inactive CD_0092S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 1; age (years): 20; gender: Male; tissue: peripheral whole blood; microarray_batch: 1
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480339
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Inactive CD_0092S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: n.a.; partial cdeis: n.a.; ibd_evolution_time (years): 1; age (years): 20; gender: Male; tissue: peripheral whole blood; microarray_batch: 1

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GSM2480340

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Inactive CD_0009S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Inactive CD_0009S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Inactive CD_0009S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileal; treatment: Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 2.5; age (years): 18; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_accession: GSM2480340
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              sample_title: Inactive CD_0009S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileal; treatment: Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 2.5; age (years): 18; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              GSM2480341

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Inactive CD_0018S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Inactive CD_0018S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Inactive CD_0018S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 18; age (years): 37; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_accession: GSM2480341
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    sample_title: Inactive CD_0018S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 18; age (years): 37; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    GSM2480342

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Inactive CD_0311S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Inactive CD_0311S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Inactive CD_0311S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 9.5; age (years): 38; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_accession: GSM2480342
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          sample_title: Inactive CD_0311S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 9.5; age (years): 38; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          GSM2480343

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Inactive CD_0349S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Inactive CD_0349S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Inactive CD_0349S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 0.4; partial cdeis: 1; ibd_evolution_time (years): 11.5; age (years): 58; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_accession: GSM2480343
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                sample_title: Inactive CD_0349S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: 5-asa; endoscopic_mayo_score: n.a.; cdeis: 0.4; partial cdeis: 1; ibd_evolution_time (years): 11.5; age (years): 58; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                GSM2480344

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Inactive CD_0149S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Inactive CD_0149S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Inactive CD_0149S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 15; age (years): 36; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_accession: GSM2480344
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      sample_title: Inactive CD_0149S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: anti-TNF; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 15; age (years): 36; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      GSM2480345

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Inactive CD_0289S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Inactive CD_0289S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • Inactive CD_0289S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileal; treatment: anti-TNF + Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 12; age (years): 42; gender: Female; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_accession: GSM2480345
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            sample_title: Inactive CD_0289S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileal; treatment: anti-TNF + Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 12; age (years): 42; gender: Female; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            GSM2480346

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Inactive CD_0410S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Treatment control marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Inactive CD_0410S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • Inactive CD_0410S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: No treatment; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 11; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_accession: GSM2480346
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  sample_title: Inactive CD_0410S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: ileocolonic; treatment: No treatment; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 11; age (years): 36; gender: Male; tissue: peripheral whole blood; microarray_batch: 2

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  GSM2480347

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Inactive CD_0432S

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Excluded: at least one selected requirement is not met. organism: Homo sapiens — Insufficient evidence. assay type: bulk RNA-seq — Insufficient evidence. specimen category: Tissue or biopsy — Does not meet requirement. specimen category excludes: Biofluid — Does not meet requirement. Study role: Case marker detected.

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  Requirements and decision evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  • organism: Homo sapiens — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    • assay type: bulk RNA-seq — Insufficient evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • The required value is not reported.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • specimen category: Tissue or biopsy — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Inactive CD_0432S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      • excluded sample type excludes: cell line, organoid, xenograft — Meets requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • Supported by the indexed evidence.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        • specimen category excludes: Biofluid — Does not meet requirement
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • The reported value differs from the selected requirement.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          • Inactive CD_0432S Human peripheral whole blood from endoscopically inactive CD patient subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: ...
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source name
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Characteristics
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: colonic; treatment: anti-TNF + Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 10; age (years): 60; gender: Male; tissue: peripheral whole blood; microarray_batch: 2
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Description
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed organism evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Indexed assay evidence
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        INFERRED · PARENT_INHERITED: Not reported
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Source
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        GEO
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        Original indexed metadata
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_accession: GSM2480347
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        sample_title: Inactive CD_0432S
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        source_name: Human peripheral whole blood from endoscopically inactive CD patient
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        characteristics: subject status: Crohn's disease (CD) patient; case_phenotype: Crohn; endoscopic_activity: Inactive; disease_extension: colonic; treatment: anti-TNF + Immunosupressors; endoscopic_mayo_score: n.a.; cdeis: 0; partial cdeis: 0; ibd_evolution_time (years): 10; age (years): 60; gender: Male; tissue: peripheral whole blood; microarray_batch: 2