Ranked GEO Datasets

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Explore premium collections with reusable study, cohort and sample curation. The matching scope is stated for each collection. Organism, tissue, comparison and sample requirements still need review; collection availability does not affect dataset ranking.

Liver Fibrosis Expression Collection

Disease scope matches your disease term.

Public liver fibrosis expression datasets with disease stage or fibrosis/control comparisons.

Preview fixture · Version v0.1-preview

Study inventory: 3 datasets
Reported sample inventory: 316 samples
Updated: 2026-06-22
Disease: Liver fibrosis
Organisms: Homo sapiens, Mus musculus
Technologies: bulk RNA-seq, microarray
Tissues: liver tissue, liver biopsy
Comparisons: fibrosis vs control, advanced fibrosis vs mild fibrosis, disease model vs control

Query overlap with this collection version
Dimension	Your query	Collection scope	Comparison
Disease	Liver fibrosis	Liver fibrosis	MATCH Declared collection scope includes this requested dimension; question-specific sample eligibility still needs review.
Specimen		liver tissue, liver biopsy	NOT_REQUESTED No explicit query requirement was supplied for this dimension.
Organism		Homo sapiens, Mus musculus	NOT_REQUESTED No explicit query requirement was supplied for this dimension.
Comparison		fibrosis vs control, advanced fibrosis vs mild fibrosis, disease model vs control	NOT_REQUESTED No explicit query requirement was supplied for this dimension.

Full access adds reusable curated cohort structure, sample decisions and provenance. Review the content status above before treating a release as professionally approved. Ordinary Search results remain available below.

Preview collection

Counts describe the collection inventory, not final eligible samples or independent subjects. Preview fixtures are illustrative; review-pending releases are not professionally approved.

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2 shown of 17 matching datasets Comparison Tumor vs normal Tissue/sample context Patient tissue Organism Any organism Assay Any assay Ranking defaults Modified 6 user changes 1 active filters Page 2 of 2 · showing 16-17

Disease/condition e.g. colorectal cancer Anatomical source Specimen material Cell population Comparison type (required) Organism Assay type Minimum samples Experimental model Exclude cell lines Require processed data GEO only recount3 available Expression Atlas available

Treatment requirements Optional See what each comparison arm must satisfy — Unrestricted

Comparison: Tumor vs normal

Case arm

Your requirement

Exposure state

Agent

Comparator

From comparison

Determined by comparison

For treatment vs control, use a named agent, an explicit collection window and an exposed or unexposed state. The comparator needs the opposite reported exposure state for the same agent, target and window.

Collection window Assertion target

Named agent if supplied; otherwise all interventions.

Scope & matching · additional options

Exposure scopeAutomatic: named agent if supplied; otherwise all interventions. Uncertain alternativesReview cases are not confirmed matches. Exact reported scope (when requested)

Missing metadata never proves no exposure.

Evidence and comparison rules

Exact results require an eligible sample subset and reported independent subjects in both arms.

“No exposure” applies only to the selected agent, target and time window. No exposure to a new agent before collection does not rule out earlier therapy.

A broader treatment history requires separate, explicit evidence and may be unavailable. All prior therapy requires a through-collection window.

Planned exposure does not establish that treatment occurred. Treatment vs control requires an exposed or unexposed state, a named agent and an explicit collection window.

Organism and specimen requirements apply to both arms. For treatment vs control, disease requirements also apply to both arms.

Genotype requirements Optional Define a requirement, then assign it to samples — Unrestricted

Genetic state Gene symbol

Apply requirement to

Specific protein variant · optional

Exact reported protein variant

Leave blank for a gene-level requirement. A variant restriction applies to every selected arm.

Genotype describes sampled material. Confirmed evidence must come from the same samples as your other requirements.

Use with human bulk RNA-seq or expression microarray.

Evidence and comparison rules

Select Homo sapiens and a supported assay in the search filters.

Missing genotype does not establish wild type. Both comparison arms still need eligible, independent samples.

A subject's carrier status does not establish the sampled tumor's genotype or disease.

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Showing one page of matching results. Use next/previous for browsing, or CSV/Markdown export for the full matching set.

Strict results

These datasets meet every active search criterion.

Treatment of advanced liver fibrosis in HIV- and HCV-infected adults with simtuzumab, a monoclonal antibody against lysyl oxidase-like 2: Results of a 6-month open-label safety trial

Select

Organization: NIH

Case liver fibrosis Control unclear

Unclear study design Mixed specimen/source

Rationale for Tumor vs normal

Dataset does not meet the current suitability threshold.

Downgraded for tissue search because specimen/source classes are mixed.
Downgraded for tissue search because study design or specimen source is unclear.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Fibrosis, HIV infection, Infectious disease or host response, Liver fibrosis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 27232579.

critical No clear control group was detected from normalized metadata. info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled. warning Patient-tissue tumor-normal intent requires clear tumor-normal grouping. warning Patient-tissue tumor-normal intent requires tissue or biopsy source clarity.

Expression data of HCV-associated advance disease state

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Organization: King Saud University

Case mixed disease cohort Control unclear

Unclear study design Biopsy

Rationale for Tumor vs normal

Dataset does not meet the current suitability threshold.

Downgraded for tissue search because study design or specimen source is unclear.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Fibrosis, Infectious disease or host response, Liver fibrosis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 21484131.

critical No clear control group was detected from normalized metadata. warning Pooled samples were detected and may need exclusion. warning Total sample count is below the minimum needed for two comparison groups. info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled. warning Patient-tissue tumor-normal intent requires clear tumor-normal grouping.