Ranked GEO Datasets

Collections related to this search

Explore premium collections with reusable study, cohort and sample curation. The matching scope is stated for each collection. Organism, tissue, comparison and sample requirements still need review; collection availability does not affect dataset ranking.

Human Sepsis Whole Blood Expression Collection

Disease scope matches your disease term.

Public whole blood or PBMC sepsis datasets with disease/control comparison.

Preview fixture · Version v0.1-preview

Study inventory: 5 datasets
Reported sample inventory: 1,276 samples
Updated: 2026-06-22
Disease: Sepsis
Organisms: Homo sapiens
Technologies: microarray, bulk RNA-seq
Tissues: whole blood, PBMC
Comparisons: sepsis vs healthy control, sepsis vs ICU control, severe sepsis vs mild sepsis

Query overlap with this collection version
Dimension	Your query	Collection scope	Comparison
Disease	Sepsis	Sepsis	MATCH Declared collection scope includes this requested dimension; question-specific sample eligibility still needs review.
Specimen		whole blood, PBMC	NOT_REQUESTED No explicit query requirement was supplied for this dimension.
Organism		Homo sapiens	NOT_REQUESTED No explicit query requirement was supplied for this dimension.
Comparison		sepsis vs healthy control, sepsis vs ICU control, severe sepsis vs mild sepsis	NOT_REQUESTED No explicit query requirement was supplied for this dimension.

Full access adds reusable curated cohort structure, sample decisions and provenance. Review the content status above before treating a release as professionally approved. Ordinary Search results remain available below.

Preview collection

Counts describe the collection inventory, not final eligible samples or independent subjects. Preview fixtures are illustrative; review-pending releases are not professionally approved.

Public previews are free. Full collections and exports require access approval. Online checkout is not available.

15 shown of 120 matching datasets Comparison Tumor vs normal Tissue/sample context Patient tissue Organism Any organism Assay Any assay Ranking defaults Modified 6 user changes 1 active filters Page 1 of 8 · showing 1-15

Disease/condition e.g. colorectal cancer Anatomical source Specimen material Cell population Comparison type (required) Organism Assay type Minimum samples Experimental model Exclude cell lines Require processed data GEO only recount3 available Expression Atlas available

Treatment requirements Optional See what each comparison arm must satisfy — Unrestricted

Comparison: Tumor vs normal

Case arm

Your requirement

Exposure state

Agent

Comparator

From comparison

Determined by comparison

For treatment vs control, use a named agent, an explicit collection window and an exposed or unexposed state. The comparator needs the opposite reported exposure state for the same agent, target and window.

Collection window Assertion target

Named agent if supplied; otherwise all interventions.

Scope & matching · additional options

Exposure scopeAutomatic: named agent if supplied; otherwise all interventions. Uncertain alternativesReview cases are not confirmed matches. Exact reported scope (when requested)

Missing metadata never proves no exposure.

Evidence and comparison rules

Exact results require an eligible sample subset and reported independent subjects in both arms.

“No exposure” applies only to the selected agent, target and time window. No exposure to a new agent before collection does not rule out earlier therapy.

A broader treatment history requires separate, explicit evidence and may be unavailable. All prior therapy requires a through-collection window.

Planned exposure does not establish that treatment occurred. Treatment vs control requires an exposed or unexposed state, a named agent and an explicit collection window.

Organism and specimen requirements apply to both arms. For treatment vs control, disease requirements also apply to both arms.

Genotype requirements Optional Define a requirement, then assign it to samples — Unrestricted

Genetic state Gene symbol

Apply requirement to

Specific protein variant · optional

Exact reported protein variant

Leave blank for a gene-level requirement. A variant restriction applies to every selected arm.

Genotype describes sampled material. Confirmed evidence must come from the same samples as your other requirements.

Use with human bulk RNA-seq or expression microarray.

Evidence and comparison rules

Select Homo sapiens and a supported assay in the search filters.

Missing genotype does not establish wild type. Both comparison arms still need eligible, independent samples.

A subject's carrier status does not establish the sampled tumor's genotype or disease.

Clear filters Ranking defaults Relax defaults

Showing one page of matching results. Use next/previous for browsing, or CSV/Markdown export for the full matching set.

Strict results

These datasets meet every active search criterion.

Gene expression profiling of immune cells from patients with acute on chronic liver failure (ACLF)

Select

Organization: GenoSplice technology

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Sepsis, Septic shock.
Processed data is available for downstream review.
External evidence: PubMed links 4 publications; 4 DOIs available: PMID 33613548, PMID 35982134, PMID 37478215, PMID 40070835.

info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Transcriptomes of human PBMCs and monocytes in sepsis patients

Select

Organization: Tel Aviv University

Case sepsis Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Sepsis.
Processed data is available for downstream review.

No warnings

Transcriptome analysis to explore the shared and distinct immune signature between severe COVID-19 and bacterial sepsis

Select

Organization: Daping Hospital, Army Medical University

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: COVID-19, Sepsis.
Processed data is available for downstream review.

warning Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected. warning Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis.

Analysis of Immune and Prognostic-Related lncRNA PRKCQ-AS1 for Predicting Prognosis and Regulating Effect in Sepsis

Select

Organization: Guangdong Pharmaceutical University

Case sepsis or systemic inflammatory response Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Infectious disease or host response, Sepsis, Systemic inflammatory response syndrome.
Processed data is available for downstream review.

warning Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.

Expression data from validation cohort of children with septic shock

Select

Organization: Cincinnati Children's Hospital Medical Center

Case sepsis or systemic inflammatory response Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Septic shock.
Processed data is available for downstream review.
External evidence: PubMed links 23 publications; 23 DOIs available: PMID 21738952, PMID 24650276, PMID 26376786, PMID 32575108, PMID 35082520.

info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Expression data for derivation of septic shock subgroups

Select

Organization: Cincinnati Children's Hospital Medical Center

Case sepsis or systemic inflammatory response Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Septic shock.
Processed data is available for downstream review.
External evidence: PubMed links 24 publications; 24 DOIs available: PMID 19624809, PMID 21738952, PMID 24650276, PMID 26376786, PMID 39315170.

info Ambiguous sample metadata was detected in 32 sample(s): GSM648630 matched "group: n/a"; GSM648631 matched "group: n/a"; GSM648632 matched "group: n/a"; additional ambiguous samples omitted. Review these samples before inclusion or manual group assignment. info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Transcriptomes of human whole blood cells in sepsis patients

Select

Organization: Peking University People's Hospital

Case sepsis or systemic inflammatory response Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Infectious disease or host response, Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 41783141.

No warnings

Next generation sequencing of human immune cell subsets across diseases

Select

Organization: Benaroya Research Institute

Case type 1 diabetes Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Amyotrophic lateral sclerosis, Metabolic disease, Sepsis, Type 1 diabetes.
Processed data is available for downstream review.

No warnings

Gene expression patterns in blood during human anaphylaxis, trauma, and sepsis

Select

Organization: Telethon Kids Institute

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 9 publications; 9 DOIs available: PMID 34228845, PMID 36583159, PMID 37469874, PMID 37662976, PMID 38628767.

Diagnosis of childhood bacterial and viral infection using host RNA expression - Meningococcal validation cohort

Select

Organization: Imperial College London

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Infectious disease or host response, Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 3 publications; 3 DOIs available: PMID 27552617, PMID 41007866, PMID 42286943.

Protein-coding and non-coding RNA expression in whole blood leukocytes of healthy subjects and critically-ill patients with sepsis or non-infectious etiology.

Select

Organization: University of Malta

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Infectious disease or host response, Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 20 publications; 20 DOIs available: PMID 33305733, PMID 35401666, PMID 35787932, PMID 35903199, PMID 36765335.

warning Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected. info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Blood transcriptome of human sepsis in an Indian cohort [Illumina array]

Select

Organization: NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS

Case mixed disease cohort Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Downgraded assay: microarray cohorts are separated from the RNA-seq intent.
Interpreted disease metadata: Sepsis, Septic shock, Severe sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 4 publications; 4 DOIs available: PMID 38363924, PMID 39586719, PMID 40129981, PMID 41947789.

info Ambiguous sample metadata was detected in 2 sample(s): GSM4075803 matched "diagnosis: NA"; GSM4075804 matched "diagnosis: NA". Review these samples before inclusion or manual group assignment. info Microarray expression context was detected; compare separately from RNA-seq cohorts. warning Multiple disease or phenotype arms were detected. The displayed grouping summarizes the full dataset; select the requested disease-specific contrast before analysis. warning Microarray datasets are downgraded in the patient-tissue tumor-normal intent unless secondary assays are explicitly enabled.

Predicting sepsis severity at first clinical presentation: the role of endotypes and mechanistic signatures

Select

Organization: University of British Columbia

Case sepsis Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 14 publications; 13 DOIs available: PMID 35027333, PMID 36250055, PMID 36690713, PMID 36920635, PMID 37090709.

No warnings

Transcriptomic characteristics and impaired immune function of patients with sepsis

Select

Organization: University of Science and Technology of China

Case sepsis Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Infectious disease or host response, Sepsis.
Processed data is available for downstream review.

No warnings

PBMCs from healthy volunteers or septic patients

Select

Organization: Chinese Academy of MedicalSciences & Peking Union Medical College

Case sepsis or systemic inflammatory response Control healthy control

Patient biofluid vs healthy control Biofluid

Rationale for Tumor vs normal

Dataset can inform exploration but is not strong enough for primary analysis.

Downgraded for tissue search because it is a biofluid cohort.
Prioritized assay: bulk RNA-seq is the active assay expectation.
Interpreted disease metadata: Sepsis.
Processed data is available for downstream review.
External evidence: PubMed links 1 publication; 1 DOI available: PMID 42143071.

No warnings