Human Sepsis Whole Blood Expression Collection - Siftome

Public whole blood or PBMC sepsis datasets with disease/control comparison.

Disease: Sepsis
Scope: Public whole blood or PBMC sepsis datasets with disease/control comparison.
Datasets: 5 datasets
Samples: 1,276 samples
Species coverage: Homo sapiens
Technology coverage: microarray, bulk RNA-seq
Main tissues: whole blood, PBMC
Main comparison types: sepsis vs healthy control, sepsis vs ICU control, severe sepsis vs mild sepsis
Curation status: MVP preview curation
Last update: 2026-06-22
Version number: v0.1-preview

Collection Workflows

5 datasets

Use this curated collection as a starting point for cohort comparison, Evidence Pack generation, or broader ranked dataset search.

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Curated cohorts: 6 curated cohorts
Evidence Pack seed: Sepsis in whole blood, PBMC
Search scope: Public whole blood or PBMC sepsis datasets with disease/control comparison.

Collection Preview

Preview access

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Technology Distribution

microarray: 3 datasets 964 samples
bulk RNA-seq: 2 datasets 312 samples

Limited Usage Notes

Biomarker validation
Disease/control expression analysis
Disease vs control expression analysis for adult sepsis whole blood and PBMC cohorts.
External validation of candidate sepsis biomarkers in independent public cohorts.

Example dataset	Tissue	Technology	Samples
GSE65682 Whole blood transcriptomic profiles in sepsis and controls	whole blood	microarray	802 samples
GSE57065 Sepsis whole blood disease-control expression study	whole blood	microarray	82 samples
GSE28750 Pediatric sepsis blood expression cohort	whole blood	microarray	80 samples